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Objectives: To examine the relationship between the English index of multiple deprivation (IMD) and the incidence of pre-eclampsia (PE), evaluate the distribution of IMD in a cohort of ethnically diverse pregnant women in South East England and assess whether IMD improves the prediction of PE compared with that provided by the ‘history-only’ competing-risks model (based on maternal characteristics
The current plastic system is unsustainable and needs to change. Plastics are mainly produced from fossil feedstock, contributing to greenhouse gas emissions, and low rate of post-consumer recycling results in pollution on land and in oceans with high ecological impact, and huge loss of valuable material. There is an urgent need to find solutions for shifting the raw material base to renewable res
Importance: Patients with amnestic mild cognitive impairment (aMCI) may progress to clinical Alzheimer disease (AD), remain stable, or revert to normal. Earlier progression to AD among patients who were β-amyloid positive vs those who were β-amyloid negative has been previously observed. Current research now accepts that a combination of biomarkers could provide greater refinement in the assessmen
Lung cancer is a common cancer type associated with poor prognosis. Even in the group of patients with earlystage tumors, for which curative treatment is possible, lung cancer recurrence is frequent. The aim of this thesis was to investigate the potential prognostic role of mutations in tumor specimens, blood-based proteins and circulating tumor DNA.In study I, we performed EGFR mutation detection
Background: Most in vitro studies of potential osteoarthritis (OA) therapies have used cartilage monocultures, even though synovium is a key player in mediating joint inflammation and, thereby, cartilage degeneration. In the case of interleukin-1 (IL-1) inhibition using its receptor antagonist (IL-1Ra), like chondrocytes, synoviocytes also express IL-1 receptors that influence intra-articular IL-1
Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon co
Introduction: The demographic changes with population ageing and a rapidly growing share of very old peoplewill put an increasing pressure on the health and social care system. In order to both restrict early retirement and force people to extend their working life reforms are changing pension systems in many European countries. Besides that older people have to extend their working life it is imp
IMPORTANCE The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. OBJECTIVE To examine the discriminative accuracy of [18F]flortaucipir for AD vs non-AD neurodegenerative disorders. DESIGN, SETTING, AND PARTICIPANTS In this cross-
Importance: Prognostication of neurologic outcome after cardiac arrest is an important but challenging aspect of patient therapy management in critical care units. Objective: To determine whether serum neurofilament light chain (NFL) levels can be used for prognostication of neurologic outcome after cardiac arrest. Design, Setting and Participants: Prospective clinical biobank study of data from t
Scientists have deemed existing protected areas in European forests insufficient to halt and reverse biodiversity loss resulting from ongoing intensification of management. In Sweden, protected areas are therefore complemented with the so-called areas of high conservation value (AHCVs), that is, landscapes encompassing both protected and assumed biodiversity-valuable areas as well as surrounding l
Background: Endometriosis and irritable bowel syndrome (IBS) have similar symptoms, pathogenesis, and risk factors. These diagnoses often coexist and are frequently misdiagnosed leading to diagnostic delays. This study of a population-based cohort aimed to investigate associations relating to endometriosis and IBS and to compare gastrointestinal symptoms between endometriosis and IBS. Method: The
Objective: To study the impact of GH dose and age at GH start in girls with Turner syndrome (TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH). However, age at diagnosis will limit treatment possibilities. Methods: National multicenter investigator-initiated studies (TNR 87-052-01 and TNR 88-072) in girls with TS, age 3–16 years at GH start during year 1987–1998
This essay investigates the need for prioritizing resilience and mindfulness in academia and elaborated on a pragmatic approach to how we as scholars can improve our well-being collectively in today’s demanding academic environment.
The baobab is among the commonly consumed wild fruits found in the semi-arid regions of sub-Saharan Africa. It has a wide application in food systems and folk medicine and has an advantage of surviving even in harsh environmental conditions. While the fruit pulp is packed with a lot of essential nutrients and has gained much interest in recent past on the international market as a healthy ‘superfo
Blood biomarkers have the potential to revolutionize Alzheimer's disease diagnosis, offering advantages over CSF and PET due to their accessibility, scalability and cost-effectiveness. This study evaluated the effectiveness of individual plasma biomarkers, such as phosphorylated Tau (pTau) 217, as well as biomarker combinations, with a focus on the pTau 217/β-Amyloid (Aβ) 1–42 ratio to predict amy
Schema för KURSNAMN 10 p (15 ECTS) VT -2 2003 Schedule for GEOM07, 15 hp (15 ECTS credits) Autumn-2 2015 Sedimentary Geology and Basin Analysis Course leader: Prof. Mikael Calner Teachers: AA = Anders Ahlberg MC = Mikael Calner ME = Mikael Erlström AL = Anders Lindskog OP = Olof Peterffy E-mail to teachers: name.surname@geol.lu.se * = Excursion/fieldwork Day Date Hours Topic Grp Room Teacher Mon 2
https://www.geology.lu.se/sites/geology.lu.se/files/geom07_schema_2015_11_05.pdf - 2026-06-04
Nyhetsbrev 2019 till dig som deltar i ett världsunikt projekt Välkomna - alla gamla och nya deltagare! GÅS-projektet startade 2001 och nu 2019 är våra team i full gång med den sjunde undersöknings- omgången. Ett av syftena med GÅS-projektet är att undersöka hur hälsan påverkas över tid. Ett annat syfte är att ta reda på hur hälsan skiljer sig åt mellan olika generationer, därför erbjuds nya deltag
https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2019_final_tg.pdf - 2026-06-04
Header 1 2021-01-25 1 Peer reviewed publications (data and/or co-authors at the national 7T facility) [1] [1-29] 1. Novén, M., Schremm, A., Horne, M., Roll, M., Cortical thickness and surface area of left anterior temporal areas affects processing of phonological cues to morphosyntax, Brain Research 2021,1750:147150 2. Wiggermann, V., Mackay, A. L., Rauscher, A., Helms, G., In vivo investigation o
https://www.lbic.lu.se/sites/lbic.lu.se/files/publications2021jan.pdf - 2026-06-04
The Malmö Diet and Cancer Study The Malmö Diet and Cancer Study Department of Clinical Sciences Skåne University Hospital, Malmö Lund University The Malmö Diet and Cancer Study The EPIC cohort Vital Status – Cancer Endpoints End of follow-up: 31 December 2016 Report: 16 November 2017 1. Cohort 2. Lost to follow-up 3. Vital status 4. Time of follow-up 5. Cause-of-death 6. Cancer endpoints Anders Da
https://www.malmo-kohorter.lu.se/sites/malmo-kohorter.lu.se/files/mdc_vital_cancer_endpoint_report_2017.pdf - 2026-06-04
