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Streptococcus pyogenes can cause invasive disease with high mortality despite adequate antibiotic treatments. To address this unmet need, we have previously generated an opsonic IgG1 monoclonal antibody, Ab25, targeting the bacterial M protein. Here, we engineer the IgG2-4 subclasses of Ab25. Despite having reduced binding, the IgG3 version promotes stronger phagocytosis of bacteria. Using atomic

The tendency to buy expensive and unnecessary goods is a pattern of consumer behavior that is becoming all too common in our society. We consume luxury items to satisfy practical needs that are already satisfied in the quest toward self-fulfillment, or simply to impress those around us. The phenomenon of “status consumption” has become increasingly evident in modern society. Although conspicuous c

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/siemens-energy-ab/nyhetsbrev/asi-nyhetsbrev-0625.pdf - 2026-05-24

UTVÄRDERING KURS 7 HT17 PSPR07, Kurs 7: Psykoterapi - psykoterapeutisk teori, 20 Högskolepoäng. Respektive avsnitt är i huvudsak författat av delkursansvarig 7:1 Sean Perrin, 7:2 Terese Petersson, 7:3 Jens Knutsson och 7:4 Eva Malmberg. Fördjupad utvärdering av kurs 7:1, höstterminen 2017 Kurs 7:1. Introduktion till psykoterapi och psykoterapiforskning, 4 hp (N = 7/35 = 20%) Kursgrupp Psychotherap

https://www.psy.lu.se/sites/psy.lu.se/files/psp-bil_4-2018_p4c_7_vt_18_fordjupad_utvardering.pdf - 2026-05-25

Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds of natural or anthropogenic origin. Biological life can for instance respond to chemical stressors by changes in gene expression, and thus, certain gene transcripts can potentially function as biomarkers, i.e. early warnings, of toxicity and chemical stress. A major challenge for biomarker applicati

The immune processes associated with atherogenesis have received considerable attention during recent years. IgG FcRs (FcgammaR) are involved in activating the immune system and in maintaining peripheral tolerance. However, the role of the inhibitory IgG receptor FcgammaRIIB in atherosclerosis has not been defined. Bone marrow cells from FcgammaRIIB-deficient mice and C57BL/6 control mice were tra

Conference 2024 You will find recorded presentations from the conference on the Sound Environment Centre's Youtube Channel. Link to the Sound Environment Centre's Youtube Channel  About the ConferenceThis one-day conference marks the 20th anniversary of the Sound Environment Centre. The centre was initiated in 2004 and established in 2005, with the ambition to bring ideas about soundscape and acou

https://www.lmc.lu.se/aktiviteter/aktiviteter-2024/20-years-sound-environments - 2026-05-23

Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality 12 <= Q(2) = 60 GeV2 and of the Bjorken scaling variable 0.0002 <= x <= 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured

Föreläsning – Biologibloggen Hoppa till huvudinnehåll Om Biologibloggen Tillgänglighet Kontakt Sök Sök Stäng Meny Biologibloggen Biologiska institutionen | Lunds universitet Arkiv för kategorin Föreläsning Sida 1 / 9 mars 10, 2023 | Inger Ekström Under ytan bland solfjädermaskar och fytoplankton Igår var det tandem talk i Blå hallen. Karin Rengefors och Mike Bok var föreläsarna för dagen. Efter at

https://biologi.blogg.lu.se/category/forelasning/ - 2026-05-24

https://www.ub.lu.se/sites/ub.lu.se/files/2022-05/Program%20ESSUG%20anv%C3%A4ndardagar%2026-27%20april.pdf - 2026-05-25

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Immunoglobulin G (IgG) glycosylation modulates antibody activity and represents a major source of heterogeneity within antibody preparations. Depending on their glycosylation pattern, individual IgG glycovariants present in recombinant antibody preparations may trigger effects ranging from enhanced pro-inflammatory activity to increased anti-inflammatory activity. In contrast, reduction of IgG gly

Protein kinase C (PKC) plays a prominent role in immune signaling, and the paradigms for isoform selective signaling are beginning to be elucidated. Real-time microscopy was combined with molecular and biochemical approaches to demonstrate a role for PKC-epsilon in Fcgamma receptor (FcgammaR)-dependent phagocytosis. RAW 264.7 macrophages were transfected with GFP-conjugated PKC isoforms, and GFP m

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of