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There is strong evidence that climate change has a direct impact on humans and extreme temperatures have been linked to negative health impacts and increasing mortality. The heat wave of 2018 caused up to 8.2% more deaths compared to the year before in Sweden, with higher impacts in other parts of the world. The fact that people spent almost 90% of their times indoors makes the indoor environment

The main monitoring method during labor is cardiotocography, CTG, which measures the fetal heartbeat, FHR, as well as the uterine contractions, TOCO. The CTG is a valuable tool in assessing the fetal status and it is evaluated intermittently by clinicians during the progress of the labor. However, abnormalities in the CTG are often non-specific which makes the interpretation difficult and inconsis

Lifestyle modifications could be crucial in preventing and managing type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD), including diet and postprandial glycaemic control. Previous studies on the effects of polar lipids (PLs) on postprandial metabolic responses at Lund University have shown conflicting results. To reconcile these findings and contribute to the existing literature, th

The triple planetary crisis exerts high pressure on countries to transform their current economic system. The transition to a green economy is not only necessary to ensure sustainable development but also essential for countries to remain economically competitive. The neighbouring countries Panama and Costa Rica are both facing significant challenges under the green transition, despite their diffe

Efforts to regulate transnational corporations in the context of human rights are not new. They traced back to the early 1970s, when the United Nations first initiated attempts to study the impact of transnational corporations on the international development process and proposed a United Nations Code of Conduct on Transnational Corporations, an initiative that ultimately stalled. A renewed attemp

This study investigates the routinization of Electronic Health Records (EHR) systems in a Chinese hospital setting, focusing on Yangzhou University Hospital. Utilizing Adaptive Structuration Theory (AST), the research explores the complex interplay between technolo-gy, human agency, and organizational structures in the context of EHR implementation. The study reveals challenges in interoperability

As mass timber construction gains momentum worldwide, cross-laminated timber (CLT) has emerged as an important material in the built environment. However, the combustible nature of wood presents challenges and fire safety concerns, and a key interest with respect to CLT is the adhesive bond line. CLT is commonly used in ceiling configuration, and current fire stability evaluations rely predominant

Objectives: To examine the effects of thiopurine exposure during pregnancy on intrahepatic cholestasis of pregnancy (ICP) in systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) pregnancies using nationwide data from Swedish healthcare registers. Methods: This register-based cohort study included all singleton pregnancies with prevalent SLE or IBD in Sweden, 2007-2022. Exposure

Background: Cognitive impairment in trauma-affected refugees is often unassessed due to the absence of suitable cross-cultural neuropsychological measures, the high prevalence of psychiatric symptoms, and the need for interpreter mediation. This poses both a clinical challenge and a health inequality for trauma-affected refugees who are left without access to much needed rehabilitation. Untreated

Breath-hold ECG-gated cardiovascular magnetic resonance (CMR) imaging is challenging during exercise due to motion, ECG-problems, and lengthy scans. To facilitate time-resolved volumetric measures from exercise-CMR, we aimed to develop a method for constructing time-resolved ventricular cines from real-time free-breathing exercise-CMR. Time-resolved ventricular cines were semi-automatically constr

Background: The aim of this study was to develop a method for personalized training of Deep Neural Networks by means of an MRI simulator to improve MOLLI native T1 estimates relative to conventional fitting methods. Methods: The proposed Personalized Training Neural Network (PTNN) for T1 mapping was based on a neural network which was trained with simulated MOLLI signals generated for each individ

OBJECTIVE: To estimate the prevalence and predictors of sustained remission (SR) in patients with psoriatic arthritis (PsA) receiving biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) in Sweden. METHODS: All patients with PsA initiating b/tsDMARDs and who were registered in the national Swedish Rheumatology Quality Register (SRQ) from April 1999 to December 2019 wer

Individuals can gain substantial benefits from collective actions.1,2,3,4,5,6,7 However, collective behaviors introduce new challenges, like coordinating actions, maintaining cohesion, and meeting the needs of different individuals. When making collective movements, leaders are typically thought to gain disproportionate benefits through the choice of more beneficial resources3 and/or earlier acces

Background: Previous reports from relatively small clinical cohorts have suggested that the clinical presentation of obstructive sleep apnea (OSA) differs between men and women. Objective: We aimed to explore sex differences in clinical and polysomnographic features of OSA in a large nationwide registry. Methods: Participants from the ongoing Turkish Sleep Apnea Database (TURKAPNE) Study from 34 c

Background: The impact of surgical specialization on long-term survival in patients undergoing emergent colon cancer resections remains unclear. Method: A retrospective analysis was conducted on all patients who underwent emergent colon cancer resections at a secondary care hospital between 2010 and 2020. The most senior surgeon performing the procedures was classified as colorectal surgeon (CS) o

Climate warming is expected to influence the prevalence of vector-transmitted parasites. Understanding the extent to which this is ongoing, or has already occurred, requires empirical data from populations monitored over long periods of time, but these studies are sparse. Further, vector-disease research involving human health is often influenced by disease control efforts that supersede natural t

Methanol can be produced renewably and used in compression ignition (CI) engines as a replacement for fossil diesel. However, methanol is a low cetane fuel, creating challenges in achieving stable operation, particularly at low load. One potential solution is through surface ignition via a glow plug. In this work, experiments were conducted on a methanol-fueled 2.1 L single cylinder engine instrum

Objective: To evaluate the causal effect of genetically predicted serum urate (SU) levels on the risk of overall and major site-specific cancers in individuals of European ancestry, using Mendelian randomization (MR) analysis. Method: Data from two population-based cohorts from southern Sweden, the Malmö Diet and Cancer Study (MDCS) and Malmö Preventive Project (MPP), and summary-statistics data f

We investigated integrative physiological responses to eupnoeic exercise (EX), rebreathing exercise (RB), dynamic apnoea (DA) and dynamic apnoea with cold-water face immersion (DAFI) in 20 healthy participants. Trials involved non-steady-state cycle exercise at 60 W for an average duration of 66 s. With increases in heart rate and stroke volume, EX and RB increased cardiac output compared with bas