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Risk of preeclampsia and gestational diabetes after occupational exposure to chemicals during pregnancy–A cohort study of births in Sweden 1994–2014

Many women are occupationally active during pregnancy. The aim of this study was to investigate associations between exposure to chemicals during pregnancy and the risk of gestational diabetes or preeclampsia. The cohort included singleton births in Sweden between 1994 and 2014. The cohort was limited to low-educated mothers to reduce potential confounding from unidentified life-style associated f

Heteroplasmy of mutant mitochondrial DNA A10398G and analysis of its prognostic value in non-small cell lung cancer

Mitochondrial dysfunction is associated with pathogenic mitochondrial (mt)DNA mutations. The majority of mtDNA point mutations have a heteroplasmic status, which is defined as the coexistence of wild-type and mutated DNA within a cell or tissue. Previous findings demonstrated that certain mtDNA heteroplasmic mutations contribute to widely spread chronic diseases, including cancer, and alterations

Mechanical chest compressions for cardiac arrest in the cath-lab : When is it enough and who should go to extracorporeal cardio pulmonary resuscitation?

Background: Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and more aggressive treatment modalities, including extracorporeal CPR are becoming more common. The cath-lab setting enables monitoring of vital physiological parameters and other clini

Rethinking TNM : Tumor deposit-based prognostic models may improve N-staging in colorectal cancer

Introduction: Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel progn

Stuck in a neither/nor. : The impact of over-indebtedness on young people’s entry into adulthood

Based on in-depth interviews with young people experiencing over-indebtedness in Sweden, the paper illustrates the social consequences of over-indebtedness among young adults, particularly in terms of how debt problems affect the entry into adulthood. Combining theories of the indebted subject, social exclusion, emerging adulthood and liminality, the analysis shows that over-indebted young subjectBased on in-depth interviews with young people experiencing over-indebtedness in Sweden, the paper illustrates the social consequences of over-indebtedness among young adults, particularly in terms of how debt problems affect the entry into adulthood. Combining theories of the indebted subject, social exclusion, emerging adulthood and liminality, the analysis shows that over-indebted young subject

Gaia Data Release 2 : Kinematics of globular clusters and dwarf galaxies around the Milky Way

Context. Aims. The goal of this paper is to demonstrate the outstanding quality of the second data release of the Gaia mission and its power for constraining many different aspects of the dynamics of the satellites of the Milky Way. We focus here on determining the proper motions of 75 Galactic globular clusters, nine dwarf spheroidal galaxies, one ultra-faint system, and the Large and Small Mage

Testing the International Standards Organization Verification and Validation protocol for evacuation simulations-An application to the FDS+Evac model

Nowadays, many evacuation models exist in the market, and new models are continuously released with new features. How to assess the usability and reliability of model results becomes an issue for both developers and users. Therefore, verification and validation (V&V) protocols were introduced in the assessment process of evacuation models. To conduct V&V of a model, a widely accepted test

Spinning facts. Of spin, post-truth and the instrumentalisation of science. A case study from Denmark

Connecting science to political agenda-setting is essential for a sustainable transition and acceptable politics. This task is complicated by phenomena like post-truth, for which facts are a non-issue. However, post-truth is not the only issue. The practice of political spin, in which the significance of facts is reconstructed according to specific interests poses another threat to scientific cred

The need to focus on plastic in terrestrial environments: Do micro- and nanoplastic affect microorganisms in soil?

Fokus på plast i mark och jord: mikroplasters effekt på organismer i jord undersökt med ny teknologi inom jordekologi frågor. De enorma plastutsläppen till naturen är idag ett välkänt problem. Det är också välkänt att plast bryts ner till mindre partiklar med andra effekter, så kallade mikro- och nanoplaster. Allmänheten har visat stort intresse kring plastproblematiken i haven och mycket forskniThis study aims to investigate if micro- and nanoparticles of polystyrene affect microorganisms in soil. This was tested by using microfluidic chips, which are new for investigation of soil ecology questions, providing artificial channels reflecting soil conditions as well as being transparent for seeing real-time interactions. Eight microfluidic chips were made; four were filled with a micro- and

Markanvändning vid byggnation av höghastighetsjärnväg; en jämförelsestudie mellan höghastighetsjärnväg på bank och höghastighetsjärnväg på viadukt.

In the construction of high-speed railways, an important starting point is to make as little Intrusion on land as possible, therefore it is of high importance to carefully investigate which construction alternatives are the most advantageous. The purpose of this work is to compare and evaluate land use and building on viaduct. The work will be based on literature and interview studies. Sections of

In vivo evaluation of electron mediators for the reduction of methemoglobin encapsulated in liposomes by using electron energies produced by red blood cell glycolysis

Previous studies clarified that the electron enriched NADH and NADPH by RBC glycolysis could be used in an extracellular chemical reaction, where electron energies are extracted by an electron mediator methylene blue (MB). The reduced form of MB permeates the phospholipid bilayer of liposomes and reduce encapsulated ferric methemoglobin (metHb) to ferrous hemoglobin. Moreover, in vitro screening s

Evaluation of wire-line well logs from the borehole Kyrkheddinge-4 by comparison to measured core data

Populärvetenskaplig sammanfattning: Utvärdering av borrhålsloggar. Syftet med detta examensarbete var att göra en utvärdering av wireline borrhålsloggar från borrhålet Kyrkheddinge-4, 3 km öster om Staffanstorp i Skåne. Den undersökta delen av borrhålet Kyrkheddinge-4 befinner sig inom den potentiella reservoarsandstenen, Lundasandstenen. Wireline borrhålsloggar är geofysiska verktyg som används This study is an evaluation of formation characteristics, as derived from wire-line well logs, of the Lund Member in the borehole Kyrkheddinge-4, 3 km east of Staffanstorp, Skåne, Sweden, through the comparison to measured core data. The purpose is to assess the feasibility of using some of the porosity and permeability equations and cross-plots derived for the investigated section and applying th

Emigration and Labour Market Outcomes in the CEE EU Member States: A Closer Look

This paper analyses the effects of emigration on unemployment and wages in the ten Central and Eastern European countries that joined the EU in 2004 and 2007. These countries experi-enced large migration outflows following their accession and thus lost a considerable share of their labour force. This presents a good natural experiment to study the impact of emigration on the labour market outcomes

Identification of functional synonymous variants in familial breast cancer

The genetic causes of familial breast cancer are still unclear, where only less than 20% have evident germline mutations. Most studies focus on mutations that cause a direct impact in the protein, disregarding the synonymous variants, where the codon is changed but the amino acid encoded remains the same. Synonymous variants can affect mRNA stability and translation, by differences in codon usage

Green hydrogen production in SE4, a business case for large-scale green hydrogen in SE4

As the greenhouse gas emissions keep on increasing the need for solutions to help reduce emissions across all sectors has never been greater. The European Union has pointed out green hydrogen as a step in increasing the sustainability of the energy sector in Europe. Goals has been set to boost the development of hydrogen technology since the green hydrogen production today is only existing in an i

Reproduktion:Hot mot kvinnors liv och hälsa En jämförelse mellan antikens Rom och dagens u-land

This essay approaches the reproductive health of women in the Roman empire – mainly documented by the Greek-Roman medicus Soranos – by comparing them to women in developing countries to-day, as described by WHO-reports. I have recognized similarities in many respects. Though Roman upper class women had access to the best medical care of their time they risked their lives in child-birth and by abor