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Although previous studies have investigated the association of cruciferous vegetable consumption with breast cancer risk, few studies focused on the association between bioactive components in cruciferous vegetables, glucosinolates (GSL) and isothiocyanates (ITC), and breast cancer risk. This study aimed to examine the association between consumption of cruciferous vegetables and breast cancer ris
Aims: The purpose of this study was to address the need to improve opportunities for patient participation in their health and health services. This paper reports if and how patients' preferences matched their experiences of participation in treatment for hypertension in primary healthcare and what factors were linked with having had opportunities for participation that matched one's preferences.
Background: The use of welfare technology is gaining ground in municipal eldercare and is increasingly being integrated into everyday routines. However, the meanings that eldercare personnel attach to welfare technology in the care of older recipients, and thus the domestication of welfare technology, remain largely underexplored. This study explores how eldercare personnel understand and ascribe
A carbohydrate-rich diet results in hyperglycaemia and hyperinsulinaemia; it may further induce the carcinogenesis of colorectal cancer. However, epidemiological evidence among Chinese population is quite limited. The aim of this study was to investigate total carbohydrate, non-fibre carbohydrate, total fibre, starch, dietary glycaemic index (GI) and glycaemic load (GL) in relation to colorectal c
A major limiting factor for cell therapy in Parkinson's disease is the poor survival and reinnervation capacity of grafted dopaminergic neurons, independently of the cell source. Mesenchymal stromal cells (MSCs) have high capability to regulate the local environment through the release of trophic, antiapoptotic and immunomodulatory factors. In this work, we investigated whether co-grafting of MSCs
Objectives: Dyspnea, or breathlessness, is a frequent and distressing symptom among patients with heart and lung diseases, particularly in advanced cancer stages, where it affects up to 90% of lung cancer cases. This symptom considerably diminishes quality of life, leading to physical deconditioning, increased levels of anxiety and depression, repeated hospitalizations, and elevated mortality rat
We present the design of the vacuum chamber for the LNLS 2T Hybrid Wiggler. The chamber is a 3m long, 1.2mm thick 316L SS tube, which was mechanically pressed into an elliptical shape from an originally round tube. In order to provide the necessary mechanical tolerances, the rather flexible tube is welded to lateral supports that run the complete length of the chamber. Special care has been given
BACKGROUND: The NextFood Project ( www.nextfood-project.eu) started work in 2018 to identify 'Categories of Skills' that students should be equipped with to address the upcoming global challenges within agrifood and forestry disciplines, and involved concepts such as sustainability, technological adaptation and networking. This study is based on the initial skills and competencies mapping, but tak
Introduction: Rimegepant is an oral small-molecule calcitonin gene-related peptide receptor antagonist approved in several countries for acute treatment of migraine and preventive treatment of episodic migraine in adults. This review summarizes the evidence, published to date, for the use of rimegepant as an acute or preventive treatment of migraine. Areas covered: A brief overview of migraine, th
How does discomfort affect research interviewing? Recent contributions suggest that researchers do not always experience discomfort as problematic but also as productive. We explore our experiences of, and strategies for, uncomfortable interviews. Based on experiences of interviewing right-wing populist Twitter activists in the United States and Sweden, we make four claims. First, discomfort may a
Mavacamten is a selective, allosteric, and reversible cardiac myosin inhibitor, representing the first disease-specific treatment for obstructive hypertrophic cardiomyopathy (HCM) that targets the core pathophysiological mechanism of this condition. Clinical evidence supports its efficacy in improving symptoms, cardiac function, and remodeling, thereby supplementing established treatment regimens.
High-order interactions associated with non-small cell lung cancer (NSCLC) survival may elucidate underlying molecular mechanisms and identify potential therapeutic targets. Our previous work has identified a three-way interaction among pack-year of smoking (the number of packs of cigarettes smoked per day multiplied by the number of years the person has smoked) and two DNA methylation probes (cg0
BACKGROUND: HIV viremia has been considered a cardiovascular disease (CVD) risk factor, but many studies have had insufficient data on potential confounders. We explored the association between viremia and CVD after adjusting for established risk factors and analyzed whether consideration of viremia would improve CVD prediction.METHODS: Adults from RESPOND were followed from the first date with av
Background: Teledermoscopy (TDS) emerges as an efficient tool for diagnosing skin lesions. In Sweden, double reading is the standard of care, but risk factors for misdiagnosis or mismanagement using single reader evaluations (SRE) are not well-studied. This study aimed to assess the accuracy of SRE compared with the gold standard in TDS. Methods: This retrospective cohort study involved 1,997 TDS
BACKGROUND AND AIM: Warming temperature promotes bacterial growth while extreme precipitation enhances fecal-oral route of exposures to these pathogens, particularly in resource limited settings, increasing burden of diarrheal diseases. Given climate change related increases in frequency of extreme events, there is a pressing need to develop meaningful early warning system with adequate lead time
Background: The Swedish housing stock generally maintains a high standard. However, earlier policies prioritized quantity and rapid housing production targeting a younger population, over policies that require accessible housing design. With an aging population, evidence-based policies supporting ageing in place while managing societal costs are crucial. This thesis aimed to increase the knowledge
Generative AI tools (GenAI) are increasingly used for academic tasks, including qualitative data analysis for the Scholarship of Teaching and Learning (SoTL). In our practice as academic developers, we are frequently asked for advice on whether this use for GenAI is reliable, valid, and ethical. Since this is a new field, we have not been able to answer this confidently based on published literatu
BACKGROUND: Sexual harassment (SH) is a persistent problem at workplaces around the world, including academia.OBJECTIVE: This study examines the association between SH and mental well-being among employees at Lund University (LU) in Sweden.METHODS: Data was obtained from a cross-sectional survey targeting all LU employees in 2019. SH exposure was measured using a ten-item scale capturing SH experi
Cancer is a risk factor for venous thromboembolism (VTE). We aimed to define sex-specific risk of preceding cancer in patients with a first-time VTE by conducting a nationwide Swedish registry-based study including 298 172 patients with VTE and 1 185 079 matched controls. This included 44 685 patients with a diagnosis of cancer at/or within 1 year before a VTE diagnosis. Female patients with VTE h
