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Parkinson’s disease (PD) is currently the second most common neurodegenerative disorder (after Alzheimer’s disease). PD is diagnosed on its motor symptoms, which include akinesia, bradykinesia, rigidity, postural imbalance and resting tremor. It is well established that the motor symptoms develop due to lack of dopamine in the striatum. This is caused by progressive degeneration of dopaminergic ne

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Popular Abstract in Swedish Det enteriska nervsystemet (ENS) utgör mag-tarmkanalens eget nervsystem, ibland refererat till som “the second brain” då det uppvisar stora likheter med det centrala nervsystemet (CNS). Rubbningar i ENS ger bland annat störningar i tarmens motorik. Denna avhandling handlar om två sjukdomar i mag-tarmkanalen hos barn som bägge är uttryck för en rubbad motorik; HirschspruGastrointestinal motility disorders are common in childhood and in this thesis we look at two of them, i.e. Hirschsprung´s Disease (HD) and gastroesophageal reflux disease (GERD) in five different studies. HD is a congenital disease characterized by an abscence of ganglion cells in myenteric and submucous ganglia, most commonly in the distal part of the large bowel. In Paper I, we have studied t

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Popular Abstract in Swedish Syftet med denna studie var att (I) utvärdera sambandet mellan övervikt mätt med det s.k. body mass index (BMI) och operation med höftleds- eller knäledsprotes (konstgjord led) på grund av artros, (II) utvärdera sambandet mellan mekanisk belastning på grund av yrke och operation med höftleds- eller knäledsprotes på grund av artros, (III) utvärdera naturalförloppet för eThe purpose of this study was to (I) assess the association between body mass index (BMI) and total hip replacement (THR) and total knee replacement (TKR) due to osteoarthritis (OA), (II) assess the association between the mechanical load of work and THR and TKR due to OA, (III) evaluate the natural history of radiographic hip OA with regards to THR and hip fracture, (IV) to determine the prevalen

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The intention of this thesis is to explore how four self-defined BDSM practitioners describe and understand their practices. Furthermore, I want to explore if their point of view can help us to understand BDSM in other terms than violence and battery. The interviews are semi structured and were done through instant messaging. By using grounded theory method it turned up that the informants describ

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Peel testing is used to study adhesive fracture in packaging material laminates. The focus is on improved understanding of the mechanisms that provide a laminate's adhesive properties, as measured by standard macroscopic tests. Using a specially-designed peel test load rig, peel tests are performed in-situ in a laboratory X-ray tomograph. The peel test results are analyzed using a combination of t

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PurposeThere is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.MethodSemi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky's theory of sense of coherence. The SRQR checklist was used.ResultsPatient's coping