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This dissertation, which is an analysis of the entrepreneur at the micro level, supplements and underpins the understanding and use of the entrepreneur as an agent of social change in the analysis of economic change at the macro level. The aim of the thesis is firstly to seek out and identify businessmen of our time who claim to be innovative, and secondly to un-dertake a qualitative study and ana

GPR30, or G protein-coupled estrogen receptor (GPER), is a GPCR reported to bind 17β-estradiol (E2), couple to the G proteins Gs and Gi/o, and mediate non-genomic estrogenic responses. However, controversies exist regarding the receptor pharmacological profile, effector coupling, and subcellular localization. We addressed the role of the type I PSD-95/Discs-large/ZO-1 homology (PDZ) motif at the r

The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. The focus in this thesis is the development and application of several integrated platforms to detect already established protei

This study presents the first results from an ongoing initiative to develop a multi-millennial Baltic tree-ring width (TRW) chronology consisting of 12 floating records from subfossil Scots pines (Pinus sylvestris L.) extracted from three Lithuanian peat-mining areas. The floating series have been complemented with absolutely dated TRW chronologies which were obtained from living trees growing in

Social enterprises are hybrid organizations with two institutional logics, one focusing on social goals and the other one focusing on economic profitability. Both logics set the attributes for an organization. These attributes are, for instance, goals, values, or beliefs. The presence of two different logics can generate tension in these attributes. One type of tension is belonging tension. This t

Everfresh AB är Sveriges största frukt- och grönsaksdistributör med Coop som viktigaste kund. Företaget saknar idag ett dokumenterat miljöledningssystem, deras miljöaspekter är inte heller identifierade enligt kraven i miljöledningsstandarden ISO 14001. Mitt uppdrag är att identifiera dessa samt att göra en modell som kan användas vid värdering av miljöaspekterna. Arbetet grundas på ISO 14001-stanEverfresh AB is the largest fruit and vegetable distribution company in Sweden. Coop is their most important customer. Today the company is lacking a documented environmental management system, neither are their environmental aspects identified according the demands in the environmental standard of ISO 14001. My task is to identify the environmental aspects at Everfresh AB in Helsingborg, and also

Patients treated with clopidogrel who have higher body size exhibit greater platelet reactivity than patients with lower body size. In a retrospective analysis of the FEATHER trial, we examined the relationship between platelet response to thienopyridines clopidogrel 75mg (Clop-75), prasugrel 5mg (Pras-5), and prasugrel 10mg (Pras-10) using 3 body size indices: body weight (BW), body mass index (B