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Background: C-type natriuretic peptide (CNP) is a known target for promoting growth and has been implicated as a therapeutic opportunity for the prevention and treatment of cardiovascular disease (CVD). This study aimed to explore the effect of CNP on CVD risk using the Mendelian randomization (MR) framework. Methods: Instrumental variables mimicking the effects of pharmacological intervention on
ObjectivesAn endovascular aneurysm repair (EVAR) graft is a catheter-implanted vascular prosthesis and is the preferred treatment for patients with aortic aneurysm. If an EVAR graft becomes the focus of infection, the treatment possibilities are limited as it is technically difficult to remove the graft to obtain source control. This study examines whether Pseudomonas aeruginosa and Staphylococcus
Similarity measurement has been a prevailing research topic in geographic information science. Geometric similarity measurement in scaling transformation (GSM_ST) is critical to ensure spatial data quality while balancing detailed information with distinctive features. However, GSM_ST is an uncertain problem due to subjective spatial cognition, global and local concerns, and geometric complexity.
Middle aged adults experience depression and anxiety differently than younger adults. Age may affect life circumstances, depending on accessibility of social connections, jobs, physical health, etc, as these factors influence the prevalence and symptomatology. Depression and anxiety are typically measured using rating scales; however, recent research suggests that such symptoms can be assessed by Middle aged adults experience depression and anxiety differently than younger adults. Age may affect life circumstances, depending on accessibility of social connections, jobs, physical health, etc, as these factors influence the prevalence and symptomatology. Depression and anxiety are typically measured using rating scales; however, recent research suggests that such symptoms can be assessed by
Globins are usually associated with oxygen carriage in vertebrates. However, plants also contain similar heme-containing proteins, called phytoglobins (Pgbs). Unlike conventional hemoglobin, these proteins are often linked to nitric oxide metabolism, energy metabolism and redox maintenance under hypoxic and related abiotic and biotic stress conditions. Class I and II non-symbiotic Pgbs (nsPgbs) ha
In the transition to more sustainable regional economies, the widespread adoption of green technologies is crucial. However, little is known about the geography of green technology adoption and the relationship between regional demand and supply of green technologies. In this paper, we shed light on the (regional) factors explaining whether innovation adopters use green technologies that have been
The chapter examines the role of indirect review of administrative action in Swedish law. A general description of the overall structure of the Swedish system for judicial review of administrative action is followed by a discussion about the administrative measures that cannot be reviewed in a direct review. The chapter then focuses specifically on the phenomenon of indirect judicial review in rel
Study of mass transfer in microchannels is indispensable for the design of microreactors. Gas-phase volume monitoring method has been widely used to study the mass transfer process.When using this method, bubble length was measured in most studies to calculate the bubble volume by assuming a symmetrical bubble shape. Therefore, this method is not suitable for asymmetric bubbles. The present study
In accordance with India's sustainable energy targets of achieving 175 GW of renewable energy (RE) installed capacity by 2022 and 450 GW by 2030, the role of private sector actors has become increasingly important. As presently, 96 percent of the total installed RE utilities in India are privately owned; this makes sustainability driven entrepreneurship the core of India's energy sector transition
Transitioning from linear to circular production systems requires interactions that include cross-sectoral collaboration in networks. Understanding the role of collaboration within these networks can support the transition to a circular economy. To understand cross-sectoral collaborative endeavors, this paper develops a collaboration framework for circular economy by combining and interlinking thr
The adult immune system consists of cells that emerged at various times during ontogeny. We aimed to define the relationship between developmental origin and composition of the adult B cell pool during unperturbed hematopoiesis. Lineage tracing stratified murine adult B cells based on the timing of output, revealing that a substantial portion originated within a restricted neonatal window. In addi
Individuals who sleep poorly report spending more time mind wandering during the day. However, past research has relied on self-report measures of sleep or measured mind wandering during laboratory tasks, which prevents generalization to everyday contexts. We used ambulatory assessments to examine the relations between several features of sleep (duration, fragmentation, and disturbances) and mind
OBJECTIVES: To increase the proportion of individuals with hypertension obtaining a blood pressure (BP) of less than 140/90 mmHg by improving the management of hypertension in daily life from a person-centred perspective.METHODS: In this unblinded randomized controlled trial, we tested an interactive web-based self-management system for hypertension. A total of 949 patients with hypertension from
This work evaluates the effects of static and cyclic loading conditions on the stress corrosion process in unidirectional glass/modified polyester composite in the presence of a nitric acid solution. The composites were investigated under static, cyclic, and static with overload conditions using a rectangular specimen with centrally positioned grooves. The stress corrosion process was monitored us
INTRODUCTION Self-compassion and satisfaction derived from helping others is part of healthcare providers’ professional quality of life. The aim of this study was to explore and psychometrically test two instruments measuring self-compassion and professional quality of life among midwives and nurse assistants. METHODS This was a cross-sectional study with midwives and nurse assistants working with
BACKGROUND AND OBJECTIVE: The option to treat early colon cancer (CC) with local resection, as well as trials investigating neoadjuvant treatment, has increased the importance of identifying early-stage disease in the workup. Most CC patients are T- and N-staged preoperatively with CT, although its reliability in staging early CC remains elusive. The aim of this study was to investigate CT-staging
Accurate detection of SARS-CoV-2 neutralizing antibody (nAb) is critical for assessing the immunity levels after virus infection or vaccination. As fast, cost-effective alternatives to viral infection-based assays, competitive binding (CB) assays were developed to quantitate nAb by monitoring the ability of sera to inhibit the binding of viral spike (S) protein to the angiotensin converting enzyme
The inherent flexibility of 5G networks come with a high degree of configuration and management complexity. This makes the performance outcome for UEs, more than ever, dependent on intricate configurations and interplay between algorithms at various network components. In this paper, we take initial steps towards a performance exposure system at the base station using a data-driven approach for pr
BACKGROUND: The long-term course of coronary atherosclerosis has not been studied in large nationwide cohorts. Understanding the natural history of coronary atherosclerosis could help identify patients at risk for future coronary events. METHODS AND RESULTS: All coronary artery segments with <50% luminal stenosis in patients with a first-time coronary angio-gram between 1989 and 2017 were identifi
