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For diesel engines the major exhaust problem is particulate matter and NOx emissions. To reduce NOx, exhaust gas recirculation (EGR) is often used. The behavior of the EGR-level will therefore influence the emissions and it is therefore valuable to keep track of the EGR-level. Especially during transients it is difficult to predict how the EGR-level varies. In this paper the CO2-level in the intak

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The treatment of Parkinson's disease (PD) has for over 50 years relied on dopaminergic therapies that are highly effective especially in the early years of the condition, but ultimately are limited by the development of side effects that relate to the nonphysiological stimulation of dopamine receptors including in nonstriatal areas. Targeted regenerative therapies designed to restore specifically

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Background: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of histone protein variants in PDAC patients. Methods: Liquid chromatography-tandem mass spectrometry (

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Background: Evolutionary theory predicts that antagonistically selected alleles, such as those with divergent pleiotropic effects in early and late life, may often reach intermediate population frequencies due to balancing selection, an elusive process when sought out empirically. Alternatively, genetic diversity may increase as a result of positive frequency-dependent selection and genetic purgin

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Division of reproductive behaviour and alloparental care are key aspects of many animal societies. In cooperatively breeding species, variation in helping effort and unequal task participation are frequently observed. However, the extent to which the reproductive state of an individual affects the tasks performed during offspring care remains poorly understood. In the social spider Stegodyphus dum

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This paper is part of my ongoing doctoral research centered on “Street Art and Cognitive Semiotics: The case of Athens” at the division of Cognitive Semiotics at Lund University. More concretely, in this article, a fresh approach, based on a constructive (verbo-) pictorial argument, is taken to attending the relationship between a cognitive semiotics approach and street art signs in a programmatic

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Background: The life expectancy of pancreatic cancer patients remains minimal. The disease progression may be influenced by type 2 diabetes (T2D) and inflammatory status, although important gaps persist around their joint effects on disease outcome. The aim of this study was to investigate the clinical significance of the tumour immune microenvironment on pancreatic cancer prognosis in relation to

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Innovation activities in the German business sector showed two opposing trends over the past two decades: While total innovation expenditures grew substantially, the number of firms conducting innovation activities fell sharply. In this paper, we explore the mechanisms behind the declining trend in the share of innovation active firms. Considering both input (R&D activities) and output (introd

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Background: The preference for sweet taste is partially genetically determined. The major allele of the single nucleotide polymorphism rs12033832 in the sweet taste receptor (TAS1R2) has previously been associated with lower sugar sensitivity and higher sugar intake among overweight individuals. The aim of the present study was to examine the association between dietary intake and the TAS1R2 genot

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The game plan firms must navigate in the quest of competitive advantage which is changing quickly. More and more firms acknowledge that future prosperity depends on achieving the joint goals of economic, environmental and social sustainability. This understanding has resulted in both firms and actors on the financial markets enhancing their focus on environmental, social and governance dimensions

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Objective: The purpose of this study was to clarify the clinical heterogeneity of alcohol use disorder (AUD) in a national Swedish sample of affected individuals using latent class analysis. Method: Using a Swedish population-based sample of AUD cases ascertained from medical, criminal, and pharmacy registries (n = 217,071), we applied latent class analysis to sex, externalizing and internalizing

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To reduce the load on the operator of an unmanned aerial vehicle (UAV) during long search and rescue, and monitoring missions, the concept of an automatic system is proposed, which directly on board performs a prelimi-nary analysis of images received from a high-resolution navigation video camera, determines areas of interest, and sets the position of an additional camera with a reduced viewing an

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Purpose: Although persistent offenders with histories of imprisonment and violence have disproportionate high rates of psychiatric disorders, little is known of their psychiatric healthcare utilization (HCU) and HCU-associated factors. This study aimed to explore psychiatric HCU, psychiatric morbidity, and psychotropic prescription drugs in violent offenders with a history of incarceration. Method

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A fundamental understanding of the process parameters affecting the catalytic hydrodeoxygenation (HDO) of bio-oils is of significance for enabling further progression and improvement of industrial biofuel upgrading methods. Herein, a novel demonstration and evaluation of the effect of temperature, pressure, and weight hourly space velocity in the continuous HDO of vanillin to cresol over a Ni-Mo/δ

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In this study, a narrative-based language intervention (NBLI) is evaluated in children with HL based on selected narrative outcome measures important for telling and retelling stories. Nine Danish children with slight to severe sensorineural HL in the age range of 4;11–8;8 years participated. The study had a single-arm early efficacy design. The NBLI consisted of four parts: (1) warm-up activity,

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Introduction: We investigated amyloid-burden quantification in a mixed memory clinic population. Methods: [18F]Florbetaben amyloid-PET (positron emission tomography) scans of 348 patients were visually read and quantified using the Centiloid (CL) method. General linear models were used to assess CL differences across syndromic and etiological diagnosis. Linear mixed models were fitted to assess th

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Background and Aims: Alcohol use disorder (AUD) is associated with increased risk of non-fatal suicide attempt. We aimed to measure the strength and mechanistic nature of the association between AUD and increased suicide attempt and determine any causal pathways and/or shared risk factors. Design: We used Cox proportional hazards models in population-level and co-relative analyses to evaluate the

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Objectives: To evaluate the feasibility of a population-based screening trial using prostate-specific antigen (PSA), a kallikrein panel and multiparametric magnetic resonance imaging (MRI) aimed at minimizing overdiagnosis, while retaining mortality benefit. Patients and Methods: Feasibility of the screening algorithm was evaluated in terms of participation, screening test results and cancer detec