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Analysis of human cartilage extracts by radioimmunoassay showed that the noncollagenous 148-kd cartilage matrix protein was present in extracts of tracheal cartilage but was undetectable in normal or arthritic joint cartilage, corroborating previous results with bovine cartilage samples. Concentrations of the protein in the circulation, as studied by radioimmunoassay, were greatly elevated in pati

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Sport diplomacy provides a challenging example of how diplomaticpractice is changing in light of a proliferation of actors,agendas, and modes of communication. This context hasinspired greater interest in techniques for managing the participationof others in the pursuit of desired outcomes, such asdebates surrounding multi-stakeholder diplomacy, publicdiplomacy, and soft power. However, these deba

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The purpose of dynamic asset allocation (DAA) is to overcome the challenge that changing market conditions present to traditional strategic asset allocation by adjusting portfolio weights to take advantage of favorable conditions and reduce potential drawdowns. This article proposes a new approach to DAA that is based on detection of change points without fitting a model with a fixed number of reg

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The bonding energies of the Pd 3d and the C 1s core levels have been studied for the p(2 S 2 × 2) R45°, p(3 s2 × S2) R45°, and p(4 S 2 × S 2) R45°structures of CO on Pd(100). Adsorption of CO shifts the Pd 3d surface emission to higher binding energies with the magnitude of the shift depending almost linearly on the number of Pd to CO bonds; the measured shift per bond is close to 0.5 eV. A direct

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This paper discusses the strategy of the Czech economic policy as regards the current enlargement process of the European Economic and Monetary Union (EMU). The authors discuss the validity of the Maastricht criteria for the new European Union (EU) member countries, as well as the risks and puzzles of both real and nominal convergence processes. The paper shows that current fiscal policy is the ma

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'... this ambitious project definitely succeeds in putting together coherently a relatively recent body of research, and in arguing that a new policy approach to development is needed: one that puts knowledge accumulation at its core, that recognises the complex nature of learning processes and the need of new institutions to stimulate them. For the many who believe in the urgency of revising deve

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BACKGROUND AND PURPOSE: The purpose of this study was to obtain a deeper understanding of the process of motivation for change in patients with prolonged musculoskeletal disorders and to identify factors that might influence change resulting in increased independence.METHOD: A qualitative two-year follow-up study. Data collection and analysis were performed according to the qualitative case study

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Context: It is an enigma that agile projects can succeed ‘without requirements’ when weak requirements engineering is a known cause for project failures. While agile development projects often manage well without extensive requirements test cases are commonly viewed as requirements and detailed requirements are documented as test cases.Objective: We have investigated this agile practice of using t

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Of the proteins on the surface of Streptococcus pneumoniae, one of those best able to elicit protection against pneumococcal infection is pneumococcal surface protein A (PspA). Although this protein is attached to the membrane molecule, lipoteichoic acid, which is well beneath the capsule, PspA's ability to inhibit complement deposition and killing by apolactoferrin, suggests that it must have sur

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OBJECTIVE: To determine prevalence and intensity of pain after stroke, focusing on patients' perspectives. METHODS: During a one year period, 416 first-ever stroke patients were included in the population based Lund Stroke Register. After 4 and 16 months (median), 297 patients (98% of survivors) were followed up. Worst pain intensity during the previous 48 hours was assessed on a visual analo

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BACKGROUND: Lactic acid bacteria (LAB) can restore commensal microbiomes and prevent infections. Arguably, nasal administrations of LAB may therefore be beneficial in chronic rhinosinusitis (CRS). Previous studies have examined effects of topical/nasal LAB in children with secretory otitis media, but little is as yet known about their effects on the human nasal airway. The aim of this pilot study

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We estimated the number of different human genes by relating the patterns of spontaneous mutation at the population and individual level. A geometric distribution model of mutation was used in which the average rates of nucleotide replacement (P) and mutation at a locus (p), obtained by experiment, were used to determine the estimate of the physical size of the coding genome (n) in man. The probab

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Purpose: Autosomal recessive mutations in LRBA, encoding for LPS-responsive beige-like anchor protein, were described in patients with a common variable immunodeficiency (CVID)-like disease characterized by hypogammaglobulinemia, autoimmune cytopenias, and enteropathy. Here, we detail the clinical, immunological, and genetic features of a patient with severe autoimmune manifestations. Methods: Who

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Human motion analysis in images and video, with its deeply inter-related 2D and 3D inference components, is a central computer vision problem. Yet, there are no studies that reveal how humans perceive other people in images and how accurate they are. In this paper we aim to unveil some of the processing—as well as the levels of accuracy—involved in the 3D perception of people from images by assess

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Aim: This study evaluated the musculoskeletal effects of increased physical activity on children, starting at six to nine years of age. Methods: In one school we increased the physical education of 72 girls and 100 boys to 200 minutes per week over seven years. In three other schools, 45 girls and 47 boys continued to receive 60 minutes per week. We measured areal bone mineral density (aBMD) with