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The purpose of this study was to explore and compare different countries in what motivated research participants’ decisions whether to share their de-identified data. We investigated European DIRECT (Diabetes Research on Patient Stratification) research project participants’ desire for control over sharing different types of their de-identified data, and with who data could be shared in the future
Sustainable groundwater resources management in arid areas requires early and immediate action to prevent further negative impacts on these resources. The persistent decline in the quantity and quality of groundwater in many countries has been leading to severe challenges in the present and future. In this research, the factors affecting groundwater salinization in a coastal aquifer were evaluated
We report on growth of InP-InAs core-shell nanowires and demonstration of the formation of single quantum structures, which show the Coulomb blockade effect, over entire lengths of the nanowires. The core-shell nanowires are grown by a selective area growth technique via metal-organic vapor phase epitaxy. The as-grown core-shell nanowires a
Pridopidine is a small molecule in clinical development for the treatment of Huntington’s disease. It was recently found to have high binding affinity to the sigma-1 receptor, a chaperone protein involved in cellular defense mechanisms and neuroplasticity. Here, we have evaluated the neuroprotective and neurorestorative effects of pridopidine in a unilateral 6-hydroxydopamine (6-OHDA) lesion model
Introduction: Due to demographic change, an increase in the frequency of Parkinson's disease (PD) patients is expected in the future and, thus, the identification of modifiable risk factors is urgently needed. We aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with incident PD. Methods: In 13 of the 23 centers of the European Prospective Investigation into C
BACKGROUND: Circulating C3 has been associated with diabetes and hypertension, which are the leading causes of chronic kidney disease (CKD). C3 activation is considered to contribute to several renal diseases. Here we examined whether elevated C3 concentration is associated with hospitalization due to CKD in the general population, and whether this relationship is mediated by factors such as diabe
he aim of this study was to investigate the acute effect of hydration status on glycemic regulation in healthy adults and explore underlying mechanisms. In this randomized crossover trial, 16 healthy adults (8 men, 8 women) underwent an oral glucose tolerance test (OGTT) when hypohydrated and rehydrated after 4 days of pretrial standardizat
Studies investigating tool use in animals that are not known tool users in the wild are important in helping to understand how and under what circumstances this ability might arise. Tool use appears to be uncommon in great tits (Parus major), with only a single documented observation in which a wild great tit used conifer needles to extract larvae from crevices in trees. In a laboratory-based expe
Savannas are inherently “disturbed” ecosystems, but the regularly recurring disruptions play such a fundamental ecological role (Scholes and Archer, 1997) that “episodic events” rather than “disturbance” may the more apt terminology. From an atmospheric perspective, fire is the most significant of these episodic events. Fires shape community species composition; tree to grass ratio and nutrient re
The high-pressure homogenizer (HPH) is, together with the rotor–stator mixer (RSM), the standard equipment for emulsification in many fields of chemical processing. Both give rise to intense turbulence which, in turn, gives rise to drop breakup. Previous investigations focus on average turbulent disruptive stress. However, turbulence is a stochastic phenomenon and drop breakup will be characterize
This article focuses on the development of sustainable energy systems in the Swedish local context and, specifically, on the actors that have proved to be crucial for such transitions: municipally owned energy companies. With the theoretical lens inspired by LTS's (large technical systems), the concept of the system builder was analyzed for the purpose of further understanding what characterizes t
The postwar condition – the period where war is over yet the socio-political ordering of any given postwar entity remains contested and an unchallenged peace has still to be reached – is inherently spatial. This spatiality, however, has yet be fully addressed in theoretical and analytical terms, meaning that we neither understand it in its entirety nor have the tools with which to explore it thoro
By using a phenomenologically successful Woods-Saxon potential, I study the shape and shell structure of (A) neutron drip line nuclei with 10≤N≤60, (B) neutron-rich nuclei related to the r process with 40≤N≤90, and (C) one-particle spectra in the potential provided by the nucleus Fe70 as a representative of so-called N=40 "island of inversion" (IoI) nuclei. First, the shell structure that is uniqu
An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adul
The paper presents a feasibility study for a Climate Prediction Data Assimilation System following the methodological approach of the Carbon Cycle Data Assimilation System (CCDAS). The usefulness of accurate gradient information for estimating process parameters of the spectral atmospheric circulation model PUMA on climate time-scales is investigated. Pseudo observations of the long-term mean surf
One challenge to synthetic biology is to design functional machines from natural building blocks, from individual amino acids up to larger motifs such as the coiled coil. Here we investigate a novel bipedal motor concept, the Bar-Hinge Motor (BHM), a peptide-based motor capable of executing directed motion via externally controlled conformational switching between a straight bar and a V-shaped hin
AIMS: Catheter ablation is considered the treatment of choice for many tachyarrhythmias, but convincing 'real-world' data on efficacy and safety are lacking. Using Swedish national registry data, the ablation spectrum, procedural characteristics, as well as ablation efficacy and reported adverse events are reported. METHODS AND RESULTS: Consecutive patients (≥18 years of age) undergoing catheter a
The tensions between tendencies to support and reject that can be observed in reception measures for newly-arrived students in Sweden are a consequence both of the general climate of hostility towards immigration in Europe, and features particular to Sweden. The paper summarises the historical background to the present situation, from the 1960s onwards, and points to some of the impacts for teache
Francois Bloemhof submitted his novel for teenagers, “Slinger-slinger” for the Sanlam competition for youth fiction in 1996. Eventually this prizewinner in the beginners’ category was published in 1997. The main theme of “Slinger-slinger” is the sexual awakening and identity of teenagers.A study was undertaken to obtain the opinions of teenage readers about the success of “Slinger-slinger” as a wh
