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Oral Contraceptive Use and Breast Cancer Risk : Retrospective and Prospective Analyses From a BRCA1 and BRCA2 Mutation Carrier Cohort Study

Background: For BRCA1 and BRCA2 mutation carriers, the association between oral contraceptive preparation (OCP) use and breast cancer (BC) risk is still unclear.Methods: Breast camcer risk associations were estimated from OCP data on 6030 BRCA1 and 3809 BRCA2 mutation carriers using age-dependent Cox regression, stratified by study and birth cohort. Prospective, left-truncated retrospective and fu

Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)

This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus over the definition of the core domain of long-term control and how to measure it and (ii) to prioritize future areas of research for the measurement

Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

Heart failure is a leading cause of morbidity and mortality1,2. Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their receptor (NPR1) to affect vasodilation, diuresis and natriuresis, lowering venous pressures and relieving venous congestion3–8. Recombinant natriuretic peptide infusions were deve

Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models

Idiopathic pulmonary fibrosis (IPF) is a progressive and lethal disease characterized by excessive extracellular matrix deposition. Current IPF therapies slow disease progression but do not stop or reverse it. The (myo)fibroblasts are thought to be the main cellular contributors to excessive extracellular matrix production in IPF. Here we show that fibrotic alveolar type II cells regulate producti

Mitochondrial proteome landscape unveils key insights into melanoma severity and treatment strategies

BACKGROUND: Melanoma, the deadliest form of skin cancer, exhibits resistance to conventional therapies, particularly in advanced and metastatic stages. Mitochondrial pathways, including oxidative phosphorylation and mitochondrial translation, have emerged as critical drivers of melanoma progression and therapy resistance. This study investigates the mitochondrial proteome in melanoma to uncover no

Protocolized reduction of non-resuscitation fluids versus usual care in septic shock patients (REDUSE) : a randomized multicentre feasibility trial

BACKGROUND/PURPOSE: Non-resuscitation fluids constitute the majority of fluid administered for septic shock patients in the intensive care unit (ICU). This multicentre, randomized, feasibility trial was conducted to test the hypothesis that a restrictive protocol targeting non-resuscitation fluids reduces the overall volume administered compared with usual care.METHODS: Adults with septic shock in

Use and outcome of minimally invasive pancreatic surgery in the European E-MIPS registry

BACKGROUND: The European registry for minimally invasive pancreatic surgery (E-MIPS) collects data on laparoscopic and robotic MIPS in low- and high-volume centers across Europe.METHODS: Analysis of the first year (2019) of the E-MIPS registry, including minimally invasive distal pancreatectomy (MIDP) and minimally invasive pancreatoduodenectomy (MIPD). Primary outcome was 90-day mortality.RESULTS

Critical time window of neuronal cholesterol synthesis during neurite outgrowth

Cholesterol is an essential membrane component enriched in plasma membranes, growth cones, and synapses. The brain normally synthesizes all cholesterol locally, but the contribution of individual cell types to brain cholesterol metabolism is unknown. To investigate whether cortical projection neurons in vivo essentially require cholesterol biosynthesis and which cell types support neurons, we have

SMIM1 absence is associated with reduced energy expenditure and excess weight

BACKGROUND: Obesity rates have nearly tripled in the past 50 years, and by 2030 more than 1 billion individuals worldwide are projected to be obese. This creates a significant economic strain due to the associated non-communicable diseases. The root cause is an energy expenditure imbalance, owing to an interplay of lifestyle, environmental, and genetic factors. Obesity has a polygenic genetic arch

Tove Ryden Sonesson LicThesis Web

Kappa-utan spik Exploring governance of interdependency-related risks Implications for cross-sector resilience of Swedish critical infrastructures TOVE RYDÉN SONESSON | FACULTY OF ENGINEERING | LUND UNIVERSITY Lund University Faculty of Engineering Division of Risk Management and Societal Safety ISBN 978-91-7895-941-9 9 7 8 9 1 7 8 9 5 9 4 1 9 N O RD IC S W A N E C O LA BE L 30 41 0 90 3 Pr in te

https://www.cencip.lu.se/sites/cencip.lu.se/files/2021-09/Tove%20Ryden%20Sonesson_LicThesis_Web.pdf - 2026-04-23

Lunds-universitets-kodplan-konto

Lunds universitets kodplan - Konto Lunds universitets kodplan - Konto Läs mer om kodsträngsdelen konto på Ekonomiwebben Datum: 2025-05-07 Kontotyp Kontonr Kontonamn Datum från och med Datum till och med Tillgångar 10000 Anläggningstillg prel kto Tillgångar 10300 Immat at ack ansk Tillgångar 10310 Immat at år an Tillgångar 10350 Immat at år utr an Tillgångar 10360 Immat at ack avskr Tillgångar 1037

https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2025-05/lunds-universitets-kodplan-konto.pdf - 2026-04-23

Arsberattelse-2023-ej-tillganglig

Universitetsbibliotekets årsberättelse 2021 1 Universitetsbibliotekets årsberättelse 2023 LUNDS UNIVERSITET 2 Innehåll Starka framsteg och viktiga utmaningar .............................................................. 3 HÅLLBAR VERKSAMHET ............................................................................................... 4 Vårt hållbarhetsarbete .....................................

https://www.ub.lu.se/sites/ub.lu.se/files/2024-03/arsberattelse-2023-ej-tillganglig.pdf - 2026-04-23

Claim form - Student In and Student Out

Claim form - Student In and Student Out Postal address Kammarkollegiet, 651 80 Karlstad Street address Våxnäsgatan 10, Karolinen www.kammarkollegiet.se forsakring@kammarkollegiet.se Telephone 054-22 12 00 Fax 054-15 56 10 Organisation reg. no. 202100-0829 Bankgiro 5052-5740 Claim form Student OUT For faster processing, it is important that the form is accurately filled in and personally signed. Yo

https://www.student.lth.se/fileadmin/lth/english/master/Claim_form_Student_OUT.pdf - 2026-04-23

No title

Justification and Theosis (deification) The Joint Declaration on Justification and the Dialogue between East and'West Gösta Hallonsten (Jniversidade de Lund - Suécia 248 Piero Codø reciproco (cf. Gv 13,31-35;15,I2-I3), riflesso e realizzaztone antropologi ca delle relazioni d' amore vissute nella Santissima Trinità, è dunque chiamataa scoprire in Maria il suo archetipo e la sua for- ma generatrice

https://www.ctr.lu.se/media/documents/persons/GostaHallonsten/Justif_Theosis_1.pdf - 2026-04-24

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Arbetsgivaralliansen Branschkommitté Upplevelse och Kultur Unionen Akademikerförbunden Ledarna Upplevelse och Kultur Bransch- och löneavtal 2020-2023 1 Arbetsgivaralliansen Branschkommitté Upplevelse och Kultur Unionen Akademikerförbunden Ledarna 2 Innehåll Författningar och förkortningar 3 § 1 Avtalets omfattning 4 § 2 Anställning 5 § 3 Allmänna åligganden 9 §4 Semester 10 § 5 Sjuklön 19 § 6 Förä

https://www.saco.se/globalassets/lokala-akademikerforeningar/privat/akademikerforbunden-aht/dokument/kollektivavtal/arbetsgivaralliansen-upplevelse-o-kultur-bransch--och-loneavtal-20201201---20230430.pdf - 2026-04-24

Medborgardygd : Den europeiska staden och det offentliga rummets etos

Popular Abstract in Swedish Vad innebär det att vara en god medborgare? Frågan är lika enkel och tidlös som svaret är komplext och mångfacetterat. I grunden har det att göra med hur vi tänker politik. Frågan har i sin förlängning också djup moralisk innebörd och går tillbaka på våra normativa föreställningar om det goda samhället. Svaret vi ger varierar därför med olika värden och ideal; en god meWhat does it mean to be a good citizen? Starting with Aristotle’s ethics and philosophy of friendship formulated between the private and the public in politics' and with the timeless question of what makes a society possible as a backdrop, the author outlines a possible answer. A good citizen is a virtuous citizen, and a virtuous citizen is prudent, courageous, moderate and just. In addition, a go

Rapport-lupod-140314

Rapport luPOD Lunds universitet | sektionen personaL 2014-03-14 Tack Vi i programledningen vill rikta ett stort tack till alla medarbetare, gäster, dekaner, prefekter, mentorer och deltagare som bidragit till luPOD! Ett program av detta slag byggs inte av en styrgrupp. På samma sätt som ett universitet byggs av alla människor som bidrar på olika sätt till helheten! Cecilia Agrell Johan Mauritsson

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/rapport-lupod-140314.pdf - 2026-04-24

SIMM51 NEW FINAL 211004

SIMM51_NEW FINAL 211004 1 GRADUATE SCHOOL METHODS COURSES SIMM51 The Social Scientific Research Design and Process Version 1.0 – October 2021 1 Welcome 2 What we aim to achieve 3 Formal learning outcomes for the course 3 Your course at a glance 4 Contact Information 6 Course design and learning moments 7 Supplementary Instruction (SI) 7 Who to talk to? 7 Communication during the course 7 What abou

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2021-10/SIMM51_NEW%20FINAL%20211004.pdf - 2026-04-23

SIMM48 FINAL 220304

SIMM48 FINAL 220304 1 GRADUATE SCHOOL METHODS COURSES SIMM48 Qualitative Analysis and Coding (Using Software) Version 1.0 – March 2022 SPRING 2022 2 1. WELCOME SIMM48 QUALITATIVE ANALYSIS AND CODING (USING SOFTWARE) Contact info Graduate School e-mail: master@sam.lu.se Home page: graduateschool.sam.lu.se Facebook: tinyurl.com/LUgradschoolFB Student Union Home page: samvetet.org Lund University Hom

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/2022-03/SIMM48%20FINAL%20220304.pdf - 2026-04-23