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Hydrogen energy technologies are anticipated to play a fundamental role in securing a decarbonised energy future. While the deployment of low-carbon hydrogen energy systems remains nascent and is subject to a range of techno-economic constraints, potential scalability will also hinge on social acceptance. In response, this study draws on extensive national survey data to derive a comprehensive typ
One of the larger changes in society that affected individual’s lives during the 20th century is the increase in divorce rates that happened in almost all industrialized countries. It went from being an uncommon feature reserved for the rich to a prominent part of family-life. The increase occurred against the backdrop of economic growth and the industrialization. This study constructs a data set
Fibrillar macromolecules are long, linear structures that have helical symmetry. A technique called X-ray fiber diffraction (XRFD) is often used to help solve the three-dimensional structure of fibrillar macromolecules. Models of fibrillar structure, built de novo, using homologs or using experimental data derived from other methods should be compared to this experimental XRFD data to test and ref
The recent peak in interest for artificial intelligence, partly fueled by languagemodels such as ChatGPT, is pushing the demand for machine learning and dataprocessing in everyday applications, such as self-driving cars, where low latency iscrucial and typically achieved through edge computing. The vast amount of dataprocessing required intensifies the existing performance bottleneck of the datamo
InP quantum dots have emerged as a promising ecofriendly alternative to cadmium-based QDs for next-generation display applications. However, red-emitting InP QDs synthesized via aminophosphine precursors still suffer from broad emission spectra and limited stability. In this study, we present a strain-engineered InP/ZnSe/ZnSexS1-x/ZnS QD structure featuring a gradient alloyed ZnSexS1-x shell that
Solvent cage-escape dynamics of bimolecular photoredox products in solution has been investigated computationally through a combination of molecular dynamics simulations and quantum chemical calculations. The present work focuses on the photoinduced oxidation of the organic electron donor dimethylaniline (DMA) by a Fe(III) N-heterocyclic carbene photosensitizer (Fe(III)NHC+) in two different solve
The lifelong risk of stroke following adverse pregnancy outcomes, and potential causality, are unknown. This study examined five major adverse pregnancy outcomes and long-term risk of stroke in a large population-based cohort. Methods A national cohort study was conducted of all 2 201 393 women with a singleton delivery in Sweden during 1973–2015, followed up for stroke through 2018. Cox regressio
In vivo preclinical X-ray micro-computed tomography (μCT) imaging is widely used to obtain three-dimensional anatomical information of small animals. However, the potential for radiation exposure to influence experimental outcomes necessitates accurate dose estimation. The aim of this study was to develop a robust and reproducible method for estimating and evaluating absorbed doses in small animal
Human dihydroorotate dehydrogenase (DHODH) is the rate-limiting enzyme in pyrimidine de novo synthesis and represents a promising target for cancer therapy. However, current inhibitors of DHODH have limited clinical effectiveness and adverse effects. Herein, we report NK-A 17E-233I, a novel small-molecule inhibitor of the human DHODH enzyme, identified through a prospective virtual screening metho
Context In most cases of non-islet cell tumor hypoglycemia (NICTH), high molecular weight forms of insulin-like growth factor II, commonly referred to as big IGF-II, cause hypoglycemia. MicroRNA-483 (miR-483), encoded within an intron of IGF2, has been suggested to be coexpressed with IGF-II. Objective The aim of this study is to demonstrate the utility and reliability of circulating miR-483 as a
Cytostatic pharmaceuticals are not completely removed in wastewater treatment plants (WWTPs) and may affect aquatic ecosystems. Their quantification is challenging due to variations in wastewater characteristics, which influence analytical performance. An analytical procedure has been developed, based on solid-phase extraction and liquid chromatography coupled with tandem mass spectrometry, for th
The building sector accounts for a significant portion of global final energy use and greenhouse gas emissions, demonstrating the need to find low-carbon alternatives to new construction. Adaptive reuse offers a sustainable alternative to new construction, yet early-stage assessments of reuse potential often rely on surface-level metrics, failing to consider a building's internal spatial logic. Th
This was a retrospective cross-sectional study evaluating the aetiology and antibiotic susceptibility in patients treated for suspected bacterial keratitis at Skåne University Hospital during 2019. Inclusion criteria: eyes with bacterial keratitis. Exclusion criteria: co-infection with other microbes. Primary outcome parameters: predisposing factors, causative pathogens and antibiotic susceptibili
Large cardiac rhabdomyomas can disturb hemodynamic flow. Tuberous sclerosis complex is the most common cause of cardiac rhabdomyoma in fetuses. Recently, a mammalian target of rapamycin (mTOR) inhibitor effectively treated rhabdomyomas associated with tuberous sclerosis. Here, we report the effectiveness of an mTOR inhibitor in treating a fetus with large rhabdomyomas exhibiting severe heart failu
Purpose: To assess the ability of corneal epithelial aberrations to discriminate forme fruste keratoconus (FFKC) and keratoconus (KC) from normal eyes. Methods: This prospective, case-control study enrolled 91 right eyes from 91 normal participants, 87 eyes with FFKC and 148 eyes with KC. Epithelial aberrations for the 6-mm pupil were measured using an anterior segment optical coherence tomography
OBJECTIVES: Penicillin V (PcV) is considered the first-line treatment for community-acquired pneumonia in Scandinavian countries, although data supporting this recommendation are scarce. Thus, this study aimed to compare PcV and amoxicillin regarding the risk of treatment failures in children aged >5 years and adults treated for pneumonia in primary care.METHODS: In this retrospective study of hea
There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen
The social determinants of health are important to understand for the development of a world of equal opportunities in regards of life quality and length. This thesis aimed to contribute into such research using quantative methodology on Hepatitis C infection rates. Correlations were found for multiple social factors, but the study was unable to significantly work these results into a regression.
In the quest to find a ‘least cost solution’ for climate change mitigation that do not interfere with business-as-usual, carbon trading and PES schemes were introduced. PES schemes with carbon forestry projects are implemented in the Global South as a win-win-win tool for climate change mitigation and sustainable development. In this thesis, the Ugandan carbon forestry project Trees for Global Ben
