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Postnatal development of the gastrointestinal (GI) tract in mammals is influenced, to an unknown extent, by the diet and the microflora. The aim of the current study was to clarify the role of a dietary fibre on postnatal Gl development, by studying the effects of aprebiotic oligofructose-enriched inulin preparation (Synergy 1) on GI growth and function in a suckling rat modcl Between 10 and 16 da
INTRODUCTION: Acute kidney injury (AKI) is a common problem in hospitalized patients, requiring extensive treatment and carries a high mortality rate. This study was designed to assess the epidemiology of AKI, and risk factors and outcome of patients with severe AKI in a tertiary care university hospital in Iceland.MATERIAL AND METHODS: All adult patients with measured serum creatinine (SCr) in La
Th e performance of a mean field th eory (MFT) neu ralnetwork technique for finding approximate solutions to optimi zationproblems is invest igat ed for the case of th e minimum cut graph bisection problem, which is NP- complete. We address the issues of solut ionquality, programming complexity, convergence tim es and scala bility.Both standard random gr aphs an d mor e st ruct ured geomet ric gra
This paper introduces a conceptual framework: the CPS triangle, which has evolved over four years of research on ‘older people meet robots’. It is a synthesis of domestication theory, modern social practice theory and empirical data. Case studies on the domestication of one current technology, the robotic vacuum cleaner, and two emergent technologies, the eHealth system and the service robot, prov
Recent research on the relationship between grammatical aspect and motion event cognition has shown that speakers of nonaspect languages (e.g., German, Swedish) attend to event endpoints more than speakers of aspect languages (e.g., English, Spanish). In this study, we took a perceptual learning approach to the Whorfian hypothesis, training native English speakers to categorize events either in an
The aim of this study was to add knowledge of the longitudinal associations between gaming and emotional closeness between parents and their children. We hypothesized that parent–child emotional closeness was linked to less gaming activity over time and that more gaming activity was linked to less parent–child emotional closeness over time. We also tested the moderating effect of child gender on t
Autonomic dysfunction is a prevalent feature of Parkinson's disease (PD), mediated by disease involvement of the autonomic nervous system. Chronotropic incompetence (CI) refers to inadequate increase of heart rate in response to elevated metabolic demand, partly dependent on postganglionic sympathetic tone. In a retrospective study, PD patients with/without CI were identified. We show that PD with
Across cultures and languages spontaneous speech is often accompanied bygestures. It is a popular belief that people in Italy gesture more than peoplein Northern Europe, such as in Sweden. Despite this general assumption fewstudies empirically investigate cultural differences in gesture frequency andgesture function under similar circumstances. This study compares the spokenand gestural behaviours
This study investigates the suitability of heat conduction calorimeters for determining the specific heat capacity of solid and liquid substances. Accurate and precise measurements were obtained for various substances, including water, ethylene glycol, the ionic liquid [EMIM][TCM], and copper, with relative standard deviations averaging less than 1%. Measurements on [EMIM][DCA] indicated a systema
Introduction: Milk and dairy products are major sources of protein, calcium, and other micronutrients. Milk and dairy products contribute with approximately half of the total intake of saturated fat. Saturated fat is an important determinant of plasma total and low density lipoprotein (LDL)-cholesterol levels, and a causal relationship between high LDL-cholesterol and atherosclerotic cardiovascula
Recent event-related potential (ERP) studies in language comprehension converge in finding anticipatory negativities preceding words or word segments that can be pre-activated based on either sentence contexts or phonological cues. We review these findings from different paradigms in the light of evidence from other cognitive domains in which slow negative potentials have long been associated withRecent event-related potential (ERP) studies in language comprehension converge in finding anticipatory negativities preceding words or word segments that can be pre-activated based on either sentence contexts or phonological cues. We review these findings from different paradigms in the light of evidence from other cognitive domains in which slow negative potentials have long been associated with
While excessive production of reactive oxygen species (ROS) is a characteristic hallmark of numerous diseases, clinical approaches that ameliorate oxidative stress have been unsuccessful. Here, utilizing multi-omics, we demonstrate that in cardiomyocytes, mitochondrial isocitrate dehydrogenase (IDH2) constitutes a major antioxidative defense mechanism. Paradoxically reduced expression of IDH2 asso
Despite a large literature on the importance of childhood neighborhoods for life course transitions, there is a lack of fertility studies combining a life-course perspective with detailed neighborhood measures. Addressing this gap, we use longitudinal data in which the entire population of a Swedish town is geocoded at the address-level, 1939–1967, and linked to national registers from 1968 to 201
The dysregulated immune response and inflammation resulting in severe COVID-19 are still incompletely understood. Having recently determined that aberrant death-ligand-induced cell death can cause lethal inflammation, we hypothesized that this process might also cause or contribute to inflammatory disease and lung failure following SARS-CoV-2 infection. To test this hypothesis, we developed a nove
An analysis of an out-of-equilibrium cyclic reaction network which continuously converts a minor undesired product enantiomer to the desired major enantiomer by irreversible addition of chemical fuel and irreversible elimination of spent fuel is presented. The reaction network is maintained as long as fuel is added; interrupted fuel addition drives the system towards equilibrium, but the cyclic pr
Background: OBQ11 was developed in a Swedish context. To evaluate occupational balance, accurate self-rating instruments in the native language are needed. Aim: The aim was to investigate the measurement properties of the Danish version of OBQ11, using the Rasch analysis. Method: Data for the analysis of the Danish version of OBQ11 (OBQ11-DK) was gathered online, and all full data records (n 366)
Gamma-ray bursts (GRBs), due to their high luminosities, are detected up to a redshift of 10, and thus have the potential to be vital cosmological probes of early processes in the Universe. Fulfilling this potential requires a large sample of GRBs with known redshifts, but due to observational limitations, only 11% have known redshifts (z). There have been numerous attempts to estimate redshifts v
Background & Aims: Inflammatory bowel disease (IBD) is linked to reduced female fertility, but it is unclear how fertility rates vary by histologic disease activity. Methods: Nationwide IBD cohort of Swedish women aged 15 to 44 years. We examined fertility rates during periods with vs without histologic inflammation (n = 21,046; follow-up, 1990–2016) and during periods with vs without clinical
Background: Person-centered care (PCC) is gaining increased attention. PCC concerns the whole person behind the disease and can improve care for people with long-term conditions such as multiple sclerosis (MS) and Parkinson’s disease (PD). However, there is a lack of tools to assess PCC from the patients’ perspective, particularly in outpatient care. The Person-Centered Care instrument for outpati
