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A systematic approach to controlling problem bleeds in patients with severe congenital haemophilia A and high-titre inhibitors

The presence of inhibitory antibodies to clotting factors complicates the treatment of bleeding in haemophilia patients. For patients with high-titre inhibitors, bypassing agents are essential to haemostatic management. To determine optimal treatment practices, an international panel of physicians convened to develop a systematic treatment approach for problem bleeds (i.e. bleeds that are unrespon

Aesthetic outcome, patient satisfaction, and health-related quality of life in women at high risk undergoing prophylactic mastectomy and immediate breast reconstruction.

Prophylactic mastectomy is an effective risk-reducing option in women with hereditary increased risk of breast cancer. It may be combined with immediate reconstruction, with the intention of improving aesthetic outcome and health-related quality of life. Sixty-one women underwent prophylactic mastectomy and immediate breast reconstruction in Malmö, Sweden, between 1995 and 2003. Forty women under

Bis- and tris(pyridyl)amine-oxidovanadium complexes: characteristics and insulin-mimetic potential.

Two novel vanadium complexes, [V(IV)O(bp-O)(HSO4)] (1) and [V(IV)O(bp-OH)Cl2] x CH3OH (2 x CH3OH), where bp-OH is 2-{[bis(pyrid-2-yl)methyl]amine}methylphenol, were prepared and structurally characterised. EPR spectra of methanol solutions of 2 suggest exchange of Cl- for CH3OH and partial conversion to [VO(bp-OH)(CH3OH)3]2+. Speciation studies on the VO2+-bpOH system in a water/dmso mixture (4:1

Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors

To examine possible species differences in pharmacology, rat adenosine A2A receptors were studied in PC12 (pheochromocytoma) cells, and human receptors in Chinese hamster ovary (CHO) cells transfected with the cloned human A2A receptor cDNA. Using [3H]-5-amino-7(2-phenylethyl)-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo [1,5-c]pyrimidine ([3H]-SCH 58261) as radioligand, the estimated Bmax (maximal

Clinical outcomes and resource utilization associated with haemophilia care in Europe

We conducted a multicentre, cross- sectional study of 1042 haemophilia subjects across Europe to compare various health outcomes associated with on-demand vs. prophylactic factor-substitution therapy. Demographic, medical history, and healthcare resource utilization data were analysed along with the number of bleeding events over the past 6 months. Treatment-cost data were also examined to provide

Homeward bound: Introducing a four-domain model of perceived housing in very old age

The aim of this article is to introduce an integrative and more comprehensive approach to understanding and measuring perceived housing in old age. First, four conceptual domains of subjective housing were introduced, based on the assumption that each of the domains brings a unique perspective to the understanding of perceived housing: housing satisfaction, usability in the home, meaning of home a

Napsin A (TA02) is a useful alternative to thyroid transcription factor-1 (TTF-1) for the identification of pulmonary adenocarcinoma cells in pleural effusions

The purpose of this study was to test napsin A as a diagnostic marker of metastatic lung adenocarcinoma in pleural effusions, and to compare its performance with TTF-1. Napsin A and TTF-1 reactivities were determined immunohistochemically on.formalin-fixed paraffin embedded cell blocks from 50 pleural effusion (5 mesotheliomas, 10 mesothelial proliferations, 12 pulmonary, and 23 nonpulmonary metas

A threonine residue in the M2 region of the beta1 subunit is needed for expression of functional alpha1beta1 GABA(A) receptors

Although there is a high degree of homology in the M2 transmembrane segments of alpha1 and beta1 subunits, subunit-specific effects were observed in alpha1beta1 GABA(A) receptors expressed in Spodoptera frugipedra (Sf9) cells when the conserved 13' threonine residue in the M2 transmembrane region was mutated to alanine. When threonine 263 (13') was mutated to alanine in the beta1 subunit, high-aff

Constantly Changing Lives: Experiences of People With Multiple Sclerosis

The purpose of this study was to gain an enhanced understanding of how people with multiple sclerosis (MS) experience their engagement in occupations. We interviewed 10 people and then analyzed the data gathered using the constant comparative method of grounded theory, The findings encompassed the core category "essentials of a constantly changing life," showing that along a continuum of change, t

Black holes and core expansion in massive star clusters

In this study we present the results from realistic N-body modelling of massive star clusters in the Magellanic Clouds. We have computed eight simulations with N similar to 10(5) particles; six of these were evolved for at least a Hubble time. The aim of this modelling is to examine in detail the possibility of large-scale core expansion in massive star clusters, and search for a viable dynamical

Impact of frailty on mortality, functional outcome, and health status after out-of-hospital cardiac arrest : insights from the TTM2-trial

Purpose: To explore the association of frailty with mortality, functional outcome, and health status after out-of-hospital cardiac arrest.Methods: This is a cohort-based secondary analysis of the Targeted Hypothermia versus Targeted Normothermia after out-of-hospital cardiac arrest (TTM2) trial, an international, prospective, multicentre study. Frailty was assessed using the Clinical Frailty Scale

Discrete levels in 154Dy above spin 30ħ : Evidence for terminating band structures

High-spin states in 154Dy have been studied using the TESSA2 γ-rays spectrometer following the 110Pd(48Ca,4n)154Dy reaction at a beam energy of 210 MeV. States up to 44+ and 37- have been observed. Below spin 30 the data display regular rotational behaviour which can be interpreted in terms of the cranked shell model. Above spin 30, sequences of levels connected by stretched E2 transitions, which

Radiologic Evaluation of Swallowing : The Esophagram

Swallowing problems may be due to an abnormal transportation of food and drinks from the mouth to the stomach. The esophagram aims to monitor this and to reveal abnormalities in the morphodynamic process. It is important to analyze the patient’s symptom before the examination in order to custom-tailor the radiologic approach and to be able to explain the patients symptoms. Lower motor-neuron disea

A5 icm outgoinggrantees march 2016 low

International Credit Mobility INFORMATION FOR OUTGOING GRANTEES | 1/2016 3INTERNATIONAL CREDIT MOBILITY This brochure is a collection of essential information and regulations common to all grantees from Lund Uni- versity going abroad with an ERASMUS+ International Credit Mobility (ICM) grant. We hope that your stay and academic activity at your host university will be an enriching experience that

https://www.lu.se/sites/www.lu.se/files/a5_icm_outgoinggrantees_march_2016_low.pdf - 2026-05-10

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Sveriges Farmacevtförbund Stockholm 2011-02-21 Rapport från Studieresa i USA Anna Nörby Gennerud och Malm Schiratzki från Sveriges Farmacevtförbund besökte i januari New York och Washington DC för att få kunskap och inspiration kring hur vi kan förbättra vår medlemrekrytering och medlemskommunikation, inte minst med hjälp av sociala medier. Här följer en rapport från vår resa. Vi vill understryka

https://www.saco.se/globalassets/bilder-video-och-dokument/om-saco/sacos-fackliga-stipendiefond/2010_studieresa-usa-gennerud-schiratzki.pdf - 2026-05-09

Microsoft Word - Litteraturlista_RYSA10_vt21

Microsoft Word - Litteraturlista_RYSA10_vt21 RYSA10 Litteraturlista för RYSA10, Ryska, grundkurs, 30 högskolepoäng, fastställd av Sektion 5 2019-11-29, reviderad av styrelsen för Sektion 5 2020-12-03 Obligatorisk litteratur på delkurs 1: Rysk grammatik och översättning till ryska Allmän språklära-pensum och övningsuppgifter finns upplagt på kursplattformen. Fält, Erik (2004). Da!. Kort rysk gramma

https://www.sol.lu.se/media/utbildning/dokument/kurser/RYSA10/20211/RYSA10.pdf - 2026-05-09

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Det nionde svenska arbetarhistorikermötet Abstracthäfte Notera att: • Abstractens står i bokstavsordning efter författarens efternamn. • Vid flera författare används det efternamn vars första bokstav kommer först i alfabetet, ex texten av Egefur och Ringarp, står på Egefur. • Forskare som ej närvarar vid konferensen har sina namn inom hakparentes. Li Eriksdotter Andersson, När handelspolitik blev

https://www.hist.lu.se/fileadmin/user_upload/historiska/hist/cfa/Abstracthaefte.pdf - 2026-05-09

Årsredovisning IT-enheten, 2017

Årsredovisning IT-enheten, 2017 Årsredovisning IT-enheten 2017 Årsredovisning, IT-enheten 2017 2 INNEHÅLL Året som har gått ................................................................. 3 Vår verksamhet ................................................................... 4 Avslutade projekt ................................................................. 4 Övergripande ........................

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/Arsredovisning_IT-enheten_2017.pdf - 2026-05-09

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S & P Sprache und Pragmatik Arbeitsberichte 53 Britt-Marie Ek Das Präsens als Tempus konkreter und imaginärer Bildbeschreibung 1 Britt-Marie Ek & Mikael Nystrand Das schwedische Präsens als Übersetzungsstrategie beim deutschen Referatkonjunktiv 25 Edith Ekberg Frei versus fakultativ: Über die Interpretation der Dativphrase in deutschen ditransitiven Konstruktionen aus einer konstruktionsgrammatisc

https://www.sol.lu.se/fileadmin/user_upload/amnen/tyska/Sprache___Pragmatik_Vol._53_2013.pdf - 2026-05-09