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In recent years the concern about the future of the European Union and its supposed lack of democracy, efficiency and legitimacy has increased. This concern has resulted in extensive debates and the establishment of a convention with the task to create a draft treaty for a European Constitution. The aim of this essay is to study how the three theoretical concepts, democracy, efficiency and le

This thesis focuses on the librarian’s professional identity and how this is formed. The purpose of this study is, more specifically, to discover how the professional identity of the research librarians is constructed, and which professional identity positions are avaliable during Book a librarian-meetings at Lund university. By doing this I want to establish an understanding for what Book a libra

How we choose to organize our families has changed significantly since the mid-20th century. It might be true that the nuclear family remains the most common family form. However, it has to an increasing extent been accompanied by a number of non-traditional families, including same-sex families. Naturally, this development has also affected the way we live and how we practice family life. While

BackgroundDischarge from a neonatal care unit is often experienced as a vulnerable time for parents. By communicating through digital technology, it may be possible to improve the support for parents and thereby make the transition from hospital to home less stressful.AimTo develop an eHealth device supporting the transition from hospital to home for parents with a preterm‐born child in Sweden usi

Arctic archaeologists generally accept that Dorset Paleo-Inuit (Tuniit) (c. 800 BC-1300 AD) toolkits exhibit high levels of typological uniformity across Arctic Canada and Greenland. This understanding implies that the artifacts were likely produced according to a standardized set of practices that were somehow ÷einforced over time and shared across the isolated sites and communities inhabiting th

Efficient use of assessment of urine protein excretion in nephrological practice requires adequate reference intervals. To determine the upper reference limits of urine albumin, protein HC (alpha 1-microglobulin, immunoglobulin G (IgG), orosomucoid (alpha 1-acid glycoprotein, alpha 1-antitrypsin, and kappa- and lambda-chain immunoreactivities, the concentrations of these proteins were measured in

IMPORTANCE: There is a lack of agreement on what constitutes successful outcomes for the process of health care transition (HCT) among adolescent and young adults with special health care needs.OBJECTIVE: To present HCT outcomes identified by a Delphi process with an interdisciplinary group of participants.DESIGN, SETTING, AND PARTICIPANTS: A Delphi method involving 3 stages was deployed to refine

This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils. C57BL/6 wild-type (WT) and AnxA1 knockout mice (AnxA1-/-) received 0.3% carrageenan intraperitoneally and, after 3 h, the peritoneal exudate was collected. WT and AnxA1-/- neutrophils were then stimulated with lipopolysaccharide, followed by t

This chapter aims to discuss the phenomenon of altering the telos of a treaty by changing the focus of its object and purpose through treaty implementation. To examine the consequences in international law of altering the telos of a treaty, this contribution uses the example of the 2017 Treaty on the Prohibition of Nuclear Weapons (TPNW) against the backdrop of the considerations regarding a possi

Green fluorescent protein (GFP) from Aequorea victoria was used as an in vivo reporter protein when fused to the carboxy-terminus of the Pho84 phosphate permease of Saccharomyces cerevisiae. Both components of the fusion protein displayed their native functions and revealed a cellular localization and degradation of the Pho84-GFP chimera consistent with the behavior of the wild-type Pho84 protein.

This work presents a photodissociation study of the diamondoid adamantane using extreme ultraviolet femtosecond pulses. The fragmentation dynamics of the dication is unraveled by the use of advanced ion and electron spectroscopy giving access to the dissociation channels as well as their energetics. To get insight into the fragmentation dynamics, we use a theoretical approach combining potential e

Background: Research is needed on how to optimize the return-to-work process for persons with mental health problems.Objective: To develop a model that explains how employer and rehabilitation professional mental health literacy may influence strategies used in the return-to-work of persons with mental health problems.Methods: A grounded theory study design was used to collect and analyse intervie

The common human pathogen Group A Streptococcus (GAS) causes superficial as well as invasive, life-threatening diseases. An increase in the occurrence of invasive GAS infection by strains of the M1 and M89 serotypes has been correlated with increased expression of the genetically and functionally linked virulence factors streptolysin O (SLO) and β-NAD+-glycohydrolase (NADase). NADase affects host

A new strategy towards tubular hydrogen-bonded polymers based on the self-assembly of isocytosine tautomers in orthogonal directions is proposed and experimentally verified, including by 1H fast magic-angle spinning (MAS) solid-state NMR. The molecular tubes obtained possess large internal diameter and tailor-made outer functionalities rendering them potential candidates for a number of applicatio

Melanoma tumors are driven by a hyperactivated mitogen-activated protein kinase (MAPK) signalling pathway, and therefore can generally be classified by mutations within the B-Raf proto-oncogene (BRAF), RAS family of proto-oncogenes, neurofibromin 1 (NF1), or other genes. At the transcriptional level, several genetic classifications of melanoma have converged on the distinction between melanogenesi

BACKGROUND: The Global Burden of Disease Study (GBD) has historically produced estimates of causes of injury such as falls but not the resulting types of injuries that occur. The objective of this study was to estimate the global incidence, prevalence and years lived with disability (YLDs) due to facial fractures and to estimate the leading injurious causes of facial fracture.METHODS: We obtained

Bladder exstrophy is a rare congenital malformation leaving the urinary bladder open in the midline of the abdomen at birth. There is a clear genetic background with chromosome aberrations, but so far, no consistent findings apart from 22q11-duplications detected in about 2%–3% of all patients. Some genes are implicated like the LZTR1, ISL1, CELSR3, and the WNT3 genes, but most are not explained m