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Genetic Variations in Type 2 Diabetes and Cardiovascular Disease: A Focus on Gene-Lifestyle Interactions and Mendelian Randomization

Type 2 diabetes (T2D) and cardiovascular disease (CVD) are highly prevalent complex diseases that result from lifestyle and genetic factors. Gene-lifestyle interactions are also believed to contribute to the etiology of these diseases. The aim of this thesis was to investigate gene-lifestyle interactions using the strongest T2D and CVD susceptibility genetic loci and to understand the causal natur

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA.

Specific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite for the creation of attenuated viruses that could serve as vaccine candidates. Virus genome tailoring can be performed either by using traditionally cloned genomes as starting materials, follow

Orthopaedic measurements with computed radiography. Methodological development, accuracy, and radiation dose with special reference to the weight-bearing lower extremity and the dislocating patella

Popular Abstract in Swedish Digital bildteknik dominerar snart all bildhantering inom alla delar av samhället. Målsättningen med denna avhandling var att utveckla en undersökningsmetod för mätning av knäleden i belastat läge med hjälp av digital bildplatteteknik. Vad är bildplatteteknik? Traditionellt har röntgenbilder framställts med hjälp av fotografisk film. De framkallade bilderna har sedan The overall aim of this study was to develop and evaluate a measurement system for computed radiography (CR) and Picture Archiving and Communication Systems (PACS), permitting measurements of long distances and angles in and between related images. The developed measurement system, which was based on the QUESTOR Precision Radiography (QPR) system, was applied to the weight-bearing knee with specia

Transforming Growth Factor-b, Regulatory functions on normal lymphocytes and tumor outgrowth Regulatory functions on normal lymphocytes and tumor outgrowth

Popular Abstract in Swedish För att en multicellulär organism som männinskan ska kunna fungera måste celldelningen strikt kontrolleras. Protein som reglerar celldelning på cellulär nivå kallas för "tillväxtfaktorer". Vi har studerat ett sådant protein som kallas för transforming growth factor-beta (TGF-b). Namnet TGF-b kommer sig utav att detta protein kan transformera (omvandla) epiteliala njurceTransforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. The costimulatory effect depends on the presence of monocytes and is mediated by these cells. Furthermor

Adjuvant Hyperthermic Intraperitoneal Chemotherapy in Patients With Locally Advanced Colon Cancer (COLOPEC) : 5-Year Results of a Randomized Multicenter Trial

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has

Algeriet vid skiljevägen. Ett studium av politiska, ekonomiska och ideologiska strukturer i Algeriet 1992. Projektarbete för Försvarets Forskningsanstalt (FOA), juni – augusti 1992.

Algeriet vid skiljevägen. Ett studium av politiska, ekonomiska och ideologiska strukturer i Algeriet 1992. Projektarbete för Försvarets Forskningsanstalt (FOA), juni – augusti 1992. Torsten JansonKandidatstudent i islamologi, Lunds universitetSLUTSATSERAlgeriet 1992 - Point of no returnTvå saker om den algeriska nationen kan omedelbart konstateras: den är till sitt väsen en militärdiktatur; och de

The Ups and Downs of the Holocene: Exploring Relationships between Global CO2 and Climate Variability in the North Atlantic Region

Popular Abstract in Swedish Jordens klimat har ändrats många gånger genom dess historia. Under de senaste 2,6 miljoner åren har de kontinentala landmassorna varit geografiskt fördelade på så sätt att relativt små skillnader i Jordens omloppsbana kring solen, s.k. orbitala förändringar, har givit upphov till övergångar mellan långvariga, kalla perioder (istider) och kortvariga, varma perioder (mellThis thesis aimed to examine the relationship between climate and atmospheric CO2 concentrations through rapid climate changes during the Holocene. Climate was reconstructed using high-resolution, radiocarbon dated, lake sediment geochemical proxies (magnetic susceptibility, loss-on-ignition, total carbon/nitrogen/sulphur determinations and biogenic silica), vegetational reconstruction (pollen ana

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly genotyped) and 375,188 controls identified 54 significant (P < 5 × 10-8) loci with 68 independent single nucleotide polymorphisms. Analysis of risk estimates across geographical regions and host factors suggests the acral melanoma sub

Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3

Spinocerebellar ataxia type 3 (SCA3), caused by a CAG repeat expansion in the ataxin-3 gene (ATXN3), is characterized by neuronal polyglutamine (polyQ) ATXN3 protein aggregates. Although there is no cure for SCA3, gene-silencing approaches to reduce toxic polyQ ATXN3 showed promise in preclinical models. However, a major limitation in translating putative treatments for this rare disease to the cl

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease : a dose escalation, open-label, phase 1/2 trial

BACKGROUND: Parkinson's disease is typically treated with oral dopamine replacement therapies; however, long-term treatment leads to motor complications and, occasionally, impulse control disorders caused by intermittent stimulation of dopamine receptors and off-target effects, respectively. We aimed to assess the safety, tolerability, and efficacy of bilateral, intrastriatal delivery of ProSavin,

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Sveriges Farmacevtförbund Stockholm 2011-02-21 Rapport från Studieresa i USA Anna Nörby Gennerud och Malm Schiratzki från Sveriges Farmacevtförbund besökte i januari New York och Washington DC för att få kunskap och inspiration kring hur vi kan förbättra vår medlemrekrytering och medlemskommunikation, inte minst med hjälp av sociala medier. Här följer en rapport från vår resa. Vi vill understryka

https://www.saco.se/globalassets/bilder-video-och-dokument/om-saco/sacos-fackliga-stipendiefond/2010_studieresa-usa-gennerud-schiratzki.pdf - 2026-04-27

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ISL B20 Litteraturlista Humaniora och teo log i Centrum fö r teo log i och re l ig ionsvetenskap Litteraturlista för ISL B20 Islamologi: Fortsättningskurs, 30 hp, VT 2015 fastställd av institutionsstyrelsen 2013-11-20 och på prefektens uppdrag bekräftad av studierektor 2014-12-10 Delkurs 1. Religion och samhälle, 7,5 hp Furseth, Inger och Pål Repstad (2005). Religionssociologi – en introduktion. M

https://www.ctr.lu.se/media/utbildning/dokument/kurser/ISLB20/20151/ISL_B20_Litteratur.pdf - 2026-04-28

Navarro rhea abigail

Microsoft Word - navarro_rhea-abigail_thesis1.doc A Systems Approach on Solid Waste Management in Metro Manila, Philippines Rhea Abigail Navarro, LUMES 2002/2003 A Systems Approach on Solid Waste Management in Metro Manila, Philippines A thesis presented in partial fulfillment of the requirements of the Lund University International Master’s Programme in Environmental Science Lund University, Swed

https://www.lumes.lu.se/sites/lumes.lu.se/files/navarro_rhea_abigail.pdf - 2026-04-29

Eit-climate-kic-call-to-action-1

Holding-B.V.-letter-template CALL TO ACTION Call for Proposals for 2019 /2020 Climate Action: Transformation, in time Call to Action Announcement: Call for Proposals for 2019 and 2020 EIT Climate-KIC launched a new Strategy – Transformation, In Time - in December 2018. It says that: ‘continuing to work through gradual, incremental changes will not be enough [to successfully tackle climate change].

https://www.climate-kic.lu.se/sites/climate-kic.lu.se/files/eit-climate-kic-call-to-action-1.pdf - 2026-04-29

Litteraturlista Historisk osteologi 21-40 poäng (HOS 422)

Litteraturlista Historisk osteologi 21-40 poäng (HOS 422) Litteraturlista ARKN05. Människa, kultur, etik, 15 p ARKK01Kandidatkursen delkursen Arkeologi och etik, 5 p Litteraturlistan är delvis gemensam med kandidatkursens delkurs Arkeologi och etik. Litteratur för kandidatkursen är markerad med *. Förutom nedanstående litteraturpensum för kursen ARKN05 väljs även litteratur individuellt i samband

https://www.ark.lu.se/media/utbildning/dokument/kurser/ARKN05/20111/Litteraturlista_ARKN05.doc - 2026-04-28

Jessika luth richter hela

124218_2_250_Jessika_L Extended Producer Responsibility for Closing Material Loops Lessons from energy-efficient lighting products JESSIKA LUTH RICHTER LICENTIATE DISSERTATION |IIIEE | LUND UNIVERSITY Lund University International Institute for Industrial Environmental Economics ISBN 978-91-87357-26-8 ISSN 1402-3016 The transition to a low-carbon economy requires enabling technologies in- cluding

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/jessika_luth_richter_hela.pdf - 2026-04-29

Nutritionist

Nutritionist | Sveriges akademikers centralorganisation Hoppa till huvudinnehåll till startsida Öppna sökruta Öppna Huvudmeny Sök på saco.se Om Saco Kontakt Anställda hos Saco Saco studentråd Sacos styrelse Sacos revisorer Sacos organisation Sacos styrelse Kontaktuppgifter Sacos styrelse Verksamhetsberättelse och årsredovisning Federationen och förbunden Medlemsstatistik Förbunden Saco Hälso- och

https://www.saco.se/studier/studieval/yrken-a-o/nutritionist/ - 2026-04-27