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Sadness and other health complaints among Swedish adolescents : A cross-sectional study

Health complaints are increasing among adolescents and are recognized as a global public health issue. Health complaints are an indicator for subjective ill-being, but little is known about the relationship between sadness and other health complaints. The aim of this study was to investigate sadness and other health complaints among Swedish adolescents. A survey with a cross-sectional design was c

Management of paraesophageal hiatus hernia : recommendations following a European expert Delphi consensus

AIMS: There is considerable controversy regarding optimal management of patients with paraesophageal hiatus hernia (pHH). This survey aims at identifying recommended strategies for work-up, surgical therapy, and postoperative follow-up using Delphi methodology.METHODS: We conducted a 2-round, 33-question, web-based Delphi survey on perioperative management (preoperative work-up, surgical procedure

Michael W. Ford (The Order of Phosphorus, etc.), The Bible of the Adversary (2007)

This chapter begins by describing how Michael W. Ford founded the Order of Phosphorus (TOPH). Ford’s writings, as well as his organizations, have a pronounced eclectic approach, weaving together several religious tenets, such as Zoroastrian, Sumerian, and Western Judeo/Christian esoteric elements. The Bible of the Adversary (2007) is a key text in Ford’s Luciferian ideology. The chapter then consi

Experimental modulation and suppression of anti-allograft immune response

Abstract The objective of this investigation was to characterise the immunomodulatory or immunosuppressive effects of single drug treatment and the potential synergistic or additive effects of combined treatment with the focus on ciprofloxacin, thalidomide, mycophenolate mofetil, azathioprine, cyclophosphamide or leflunomide added to cyclosporin A (CyA). A rat cardiac transplant model was used to

Information Technology Projects: leaving the "magic" to the "wizards".

In this paper, we explore the significant challenges relating to investment in IT in business. Information technology does not in itself deliver business value. We highlight the complexities that are often ignored in management of IT projects. If the management system in an organization is ineffective, then installing information technologies does not constitute a ‘magic wand’ that will generate p

Development and validation of the predicted heat strain model

Eight laboratories participated in a concerted research project on the assessment of hot working conditions. The objectives were, among others, to co-ordinate the work of the main European research teams in the field of thermal factors and to improve the methods available to assess the risks of heat disorders at the workplace, and in particular the “Required Sweat Rate” model as presented in Inter

Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells.

The serine protease tissue-type plasminogen activator (t-PA) is involved in both vital physiological brain processes, such as synaptic plasticity, and pathophysiological conditions, such as neurodegeneration and ischemic stroke. Recent data suggest that epigenetic mechanisms play an important role in the regulation of t-PA in human endothelial cells. However, there are limited data on epigenetic r

Brain mitochondrial function in a murine model of cerebral malaria and the therapeutic effects of rhEPO.

Cerebral malaria (CM) is a life-threatening complication of Plasmodium falciparum infection. The pathogenesis of CM is complex. Cerebral metabolic dysfunction is implicated in CM, which may be caused by both an impaired cerebral microcirculation and a dysregulated inflammatory response affecting cellular respiration of mitochondria. Recombinant human erythropoietin (rhEPO) is a promising new thera

Prevalence of obstructive lung diseases and respiratory symptoms in relation to living environment and socio-economic group

We wanted to test whether living environment, occupation and social position are risk factors for asthma and chronic bronchitis/emphysema (CBE). The prevalence of bronchial asthma, CBE, respiratory symptoms and smoking habits in a random sample of 12,071 adults aged 20-59 years was assessed in a postal survey with a slightly modified questionnaire previously used in central and northern Sweden (Th

Traffic engineering of multiple spanning tree routing networks: the load balancing case

This paper deals with optimal load balancing in telecommunication networks based on multiple spanning tree routing. This is the case in switched Ethernet networks where the operator configures different routing spanning trees and assigns each demand VLAN to one of the spanning trees. We consider modeling and solving three load balancing objectives: (i) minimization of the average link load with a

Growth hormone (GH) dosing during catch-up growth guided by individual responsiveness decreases growth response variability in prepubertal children with GH deficiency or idiopathic short stature.

Context: Weight-based growth hormone (GH) dosing results in a wide variation in growth response in children with GH deficiency (GHD) or idiopathic short stature (ISS). Objective: The hypothesis tested was whether individualized GH doses, based on variation in GH responsiveness estimated by a prediction model, reduced variability in growth response around a set height target compared with a standar

Detection of Helicobacter species in liver and stomach tissues of patients with chronic liver diseases using polymerase chain reaction-denaturing gradient gel electrophoresis and immunohistochemistry

Objective. Helicobacter DNA has been detected in the hepatobiliary tree of patients with chronic liver diseases (CLD). The presence of H. pylori in the stomach compared with in the liver of the same patients with CLD has not been studied, therefore to the aim of this study was to investigate the presence of Helicobacter DNA and antigens in the liver and stomach of Polish patients with chronic live

Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system.

This study describes how the serum protein histidine-rich glycoprotein (HRG) affects the complement system. We show that HRG binds strongly to several complement proteins: C1q, factor H and C4b-binding protein and that it is found complexed with these proteins in human sera and synovial fluids of rheumatoid arthritis patients. HRG also binds C8 and to a lesser extent mannose-binding lectin, C4 and

Near-Edge x‑ray absorption fine structure investigation of the quasi-One-Dimensional organic conductor (TMTSF)2PF6

We present high-resolution near-edge X-ray absorption fine structure (NEXAFS) measurements at the P L2/3 edges, F K edge, C K edge, and Se M2/3 edges of the quasi-one-dimensional (1D) conductor and superconductor (TMTSF)2PF6. NEXAFS allows probing the donor and acceptor moieties separately; spectra were recorded between room temperature (RT) and 30 K at normal incidence. Spectra taken around RT we

Heparin pre-treatment in patients with ST-segment elevation myocardial infarction and the risk of intracoronary thrombus and total vessel occlusion. Insights from the TASTE trial

BACKGROUND: Pre-treatment with unfractionated heparin is common in ST-segment elevation myocardial infarction (STEMI) protocols, but the effect on intracoronary thrombus burden is unknown. We studied the effect of heparin pre-treatment on intracoronary thrombus burden and Thrombolysis in Myocardial Infarction (TIMI) flow prior to percutaneous coronary intervention in patients with STEMI.METHODS: T

The Effect of Family History of Diabetes and Middle Eastern Background on Abdominal Obesity is Modified by Gender: A Population based Cross-Sectional Study

Background: Abdominal obesity is on the increase worldwide and ethnic minority groups are at high risk. However, studies of the underlying causes are scarce. The aims of this study were to investigate the prevalence of abdominal obesity and to identify metabolic, lifestyle and socio-demographic risk factors associated with abdominal obesity in male and female residents of Malmö, a city in southern

Integrating the methods of project-based learning and role-playing to promote deep approach of learning : Programming languages

In recent years, there has been an increasing amount of literature on critical thinking and deep learning. Conversely, the traditional pedagogical methods of teaching lack the potentiality to make deep learning especially for the practice-oriented courses such as programming languages. Thus, this study is designed based on the Project-Based Learning (PBL) and Role-Playing (RP) which are integrated

Love thy neighbor: social sustainability assessment in built environments : the case of the Greenhouse project in Augustenborg ecocity, Malmö, Sweden

Även om en av de tre pelarna i hållbarhetstriaden bredvid den ekonomiska och miljömässiga är social hållbarhet (SS) den minst studerade och undersökta. Eftersom dess definition, mätning och drift är föremål för olika tolkningar, tenderar social hållbarhet att undervisa och ibland förbises. Denna förklarande fallstudie undersöker de sociala hållbarhetsaspekterna i det lilla samhället i Greenhouse pAlthough one of the three pillars of the sustainability triad beside the economic and environmental, Social Sustainability (SS) is the least studied and researched. Since its definition, measurement and operation are subject to different interpretations, SS tends to be undertheorized and sometimes overlooked. This explorative case study investigates the SS aspects of the small community of the Gre

Designing smart call forwarding: creating a new type of product

Nya system skapar svårigheter då man inte kan använda redan etablerade metaforer, designer eller sätt att beskriva och prata om systemet. Detta arbetet ämnar att underlätta arbetet med sådana system genom att erbjuda designprinciper och metodiker för att jobba med dem och undersöka vilka svårigheter man behöver vara medveten om. För att forma och testa nya designprinciper och metodiker så genomföOne of the difficulties in designing new products is the absence of already tried metaphors, designs or ways to talk about the system. This thesis focuses on methods and practises one could potentially use when designing something new - and if there are any challenges one need to aware of as a designer of such a system. In order to devise, and test, these practices and methods, an example system

Next Stop: Value Creation - Analysing the Potential to Enhance Public Transport Authorities’ Strategic Corporate Social Responsibility by Providing Mobility as a Service

Concepts such as Creating Shared Value [CSV] and Strategic Corporate Social Responsibility [SCSR] respond to a demand for organisations to take responsibility for their contributions to increasing social issues such as social exclusion or the effects of climate change. The concept of SCSR is describing activities that provide economic values for organisations while at the same time targeting socia