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Experiences among older persons using mobility devices

Objectives. The aim of the study was to investigate older persons' experiences of using mobility devices. Methods. In this qualitative study, focus group interviews were carried out with participants living in two municipalities in the south of Sweden. Occupational therapists and physiotherapists identified interested participants, 65 years or older. A total of 22 persons participated once in the

Epstein-Barr virus-induced transformation of human B lymphocytes : the effect of l-leucyl-l-leucine methyl ester on inhibitory T cell populations

Epstein-Barr virus-mediated transformation of human B lymphocytes is inhibited by human T lymphocytes as well as by interferon-γ. Removal of the inhibitory cell populations is essential in order to achieve successful transformation in vitro. Cells with the capacity to inhibit outgrowth of lymphoblastoid cell lines can be removed by pretreatment of peripheral blood mononuclear cells with l-leucyl-l

Size of the protein-coding genome and rate of molecular evolution

In diploid populations of size N, there will be 2 Nmu mutations per nucleotide (nt) site (or per locus) per generation (mu stands for mutation rate). If either the population or the coding genome double in size, one expects 4 Nmu mutations. What is important is not the population size per se but the number of genes (coding sites), the two being often interconverted. Here we compared the total phys

Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease

UNLABELLED: Streptococcus pneumoniae is a common human nasopharyngeal commensal colonizing 10% to 40% of healthy individuals, depending on age. Despite a low invasive disease rate, widespread carriage ensures that infection occurs often enough to make S. pneumoniae a leading bacterial cause of respiratory disease worldwide. However, the mechanisms behind transition from asymptomatic colonization t

Supporting Collaborative Healthcare Using PalCom - The itACiH System

Healthcare is increasingly a collaborative effort in- volving caregivers from several different organizations providing services to the same patient. This is particularly the case in care for the elderly and chronically ill, where a preference for care in the home is common. Current systems lack support for care scenarios that require mobility and intra-organizational collaboration. This results i

Self-initiated management strategies in digitalized work and everyday life–experiences of people with cognitive difficulties due to neurological disorders

Background: Digitalized work life can increase cognitive demands and influence people’s everyday life. This can be challenging for people with cognitive difficulties, yet there is scarce knowledge of how they manage these. It is essential to learn how self-initiated management strategies can be a resource to support sustainable work and everyday life. Aim: To describe how people with cognitive dif

Association of circulating let-7b-5p with major depressive disorder : a nested case-control study

BACKGROUND: Major depressive disorder (MDD) is one of the most common psychiatric disorders and is a great disease burden. However, its underlying pathophysiology and aetiology remain poorly understood. Available evidence suggests that circulating microRNAs (miRNAs) are associated with MDD, but it is still unknown whether miRNAs can predict subsequent incident MDD.METHODS: In this nested case-cont

Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes : The TEDDY Study

OBJECTIVE: To distinguish among predictors of seroconversion, progression to multiple autoantibodies and from multiple autoantibodies to type 1 diabetes in young children.RESEARCH DESIGN AND METHODS: Genetically high-risk newborns (n = 8,502) were followed for a median of 11.2 years (interquartile range 9.3-12.6); 835 (9.8%) developed islet autoantibodies and 283 (3.3%) were diagnosed with type 1

Neutron Diffraction Study of Indole Solvation in Deep Eutectic Systems of Choline Chloride, Malic Acid, and Water

Deep eutectic systems are currently under intense investigation to replace traditional organic solvents in a range of syntheses. Here, indole in choline chloride-malic acid deep eutectic solvent (DES) was studied as a function of water content, to identify solute interactions with the DES which affect heterocycle reactivity and selectivity, and as a proxy for biomolecule solvation. Empirical Poten

Ovarian tumor frozen section, a multidisciplinary affair

BackgroundOvarian Cancer (OC) constitute the eighth most common cancers among women worldwide. Surgery remains the cornerstone in the management of OC. Intraoperative frozen section (FS) diagnosis is widely used to decide the surgery course. We aimed to assess the reliability of intraoperative FS diagnosis for treatment planning of patients with suspected OC from a multidisciplinary perspective. T

Orthostatic Hypotension : Management of a Complex, But Common, Medical Problem

Orthostatic hypotension (OH), a common, often overlooked, disorder with many causes, is associated with debilitating symptoms, falls, syncope, cognitive impairment, and risk of death. Chronic OH, a cardinal sign of autonomic dysfunction, increases with advancing age and is commonly associated with neurodegenerative and autoimmune diseases, diabetes, hypertension, heart failure, and kidney failure.

Bjorklund stenevi brain res 1979

PII: 0006-8993(79)90472-4 Bram Research, 177 (1979) 555 560 555 c(', Elsevier/North-Holland B~omedical Press Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants ANDERS BJORKLUND and ULF STENEVI Depal tmenta o/Ht~stology and Ophthahnology, Umver,stO' of Ltmd, Lurid (Sweden) (Accepted August 9th, 1979) Surgical or neurotox~c lesions of the mgrostriatal dopamme (D

https://www.wnc.lu.se/sites/wnc.lu.se/files/bjorklund_stenevi_brain_res_1979.pdf - 2026-05-06

Cold exposure increases cyclic guanosine monophosphate in healthy women but not in women with Raynaud's phenomenon

OBJECTIVE: To investigate influence of whole-body cooling on cyclic GMP (cGMP) in women with Raynaud's phenomenon and in healthy women.DESIGN: The study was performed as an open, parallel-group comparison between women with Raynaud's phenomenon and healthy women during the winter month of February.SETTING: The municipality of Västerås (Sweden).PARTICIPANTS: The Raynaud group comprised 24 female pa

Lund University Hospital: A New Hospital and Intensive Care Unit

This thesis focuses on designing a new university hospital in Lund, addressing both technical demands and human needs. It explores the question: “How can the new hospital and intensive care unit (ICU) in Lund be designed in a way that fulfills all the technical demands, but also the more immaterial human needs?” Located on Smörlyckan, the design aligns with the competition for the “Nytt Sjukhusomr

The Right to Adequate Housing: Lessons from housing cooperatives in Uganda

This interdisciplinary research addresses the issue of adequate housing through a case study in Uganda, showcasing a framework that bridges theory and practice in participatory, community-driven housing design. Combining human rights and architecture, the study emphasises dwellers' agency as a guiding principle, empowering communities to actively shape their environments. Collaborating with th