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Sensor-augmented pump therapy lowers HbA(1c) in suboptimally controlled Type 1 diabetes; a randomized controlled trial.

Aims To investigate the efficacy of sensor-augmented pump therapy vs. multiple daily injection therapy in patients with suboptimally controlled Type 1 diabetes. Methods In this investigator-initiated multi-centre trial (the Eurythmics Trial) in eight outpatient centres in Europe, we randomized 83 patients with Type 1 diabetes (40 women) currently treated with multiple daily injections, age 18-65 y

On Legal Complexity: Between Law in Books and Planning in Practice

This chapter addresses the difference between the intentions of the law and its application by using mobile telephony infrastructure development in Sweden as a case. Three possible pitfalls for policy management in general are concluded and analyzed. The first pitfall deals with legal complexity, which may be a result of piecemeal changes to the governing legal bodies over a longer time and is her

Approaches, actors and models of vertical collaborative governance arrangements in combating poverty – five European cities compared

This chapter deals with the vertical linkages as well as the dynamics between the political, institutional and legal environments that we find between national and subnational levels of governance. By ‘vertical linkages’ we refer to collaborative governance arrangements, coordinated efforts and forms of cooperation between national, regional and local arenas. We compare the national and subnationa

A Blood Pressure Cut-Off Level Identified for Renal Failure, but not for Macrovascular Complications in Type 2 Diabetes: A 10-year Observation Study.

Abstract. AIMS: Can a cut-off blood pressure level for major complications be identified? METHODS: A 10 years observation study in 385 type 2 diabetic patients. RESULTS: 158 patients were affected with myocardial infarction, stroke, renal failure or death, which occurred in 68, 55, 19 and 109 patients, respectively. No patient with a blood pressure below 140 mmHg and/or a diastolic blood pressure

Multiple Loci in the HLA Complex Are Associated with Addison's Disease.

Context: A strong association between autoimmune Addison's disease (AAD) and major histocompatibility complex class II-encoded HLA-DRB1-DQA1-DQB1 haplotypes is well known. Recent evidence from other autoimmune diseases has suggested that class I-encoded HLA-A and HLA-B gene variants confer HLA-DRB1-DQA1-DQB1-independent effects on disease. Objective: We aimed to explore AAD predisposing effects of

Leisure time and occupational physical activity in relation to obesity and insulin resistance: a population-based study from the Skaraborg Project in Sweden.

The objective was to study obesity and insulin resistance in relation to leisure time physical activity (LTPA) and occupational physical activity (OPA) in a Swedish population, with particular focus on sex differences. Using a cross-sectional design, waist circumference, body mass index (BMI), glucose/insulin metabolism, blood pressure, heart rate, self-reported education, smoking, alcohol consump

Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.

Disturbed cellular cholesterol homeostasis may lead to accumulation of cholesterol in human atheroma plaques. Cellular cholesterol homeostasis is controlled by the sterol regulatory element-binding transcription factor 2 (SREBF-2) and the SREBF cleavage-activating protein (SCAP). We investigated whole genome expression in a series of human atherosclerotic samples from different vascular territorie

Temporary Jobs in Sweden: Incidence, Exit, and On-the-Job Training.

Popular Abstract in Swedish Denna avhandling analyserar frågor som berör tillfälliga jobb på den svenska arbetsmarknaden under perioden 1990-1999. Ett viktigt bidrag i avhandlingen är att den stora gruppen tillfälliga jobb delas upp i mindre undergrupper för att ta i beaktande den heterogenitet som finns mellan olika former av tillfälliga jobb. En röd tråd som löper genom hela avhandlingen är fokuThis thesis analyses different aspects of temporary jobs in the Swedish labour market during 1991-1999. Throughout the thesis we put special focus on differences between the genders, and differences between native-born and foreign-born workers. In chapter 1, An Introduction to Temporary Jobs in Sweden, we describe the evolution of different types of temporary jobs in Sweden during the 1990s, we re

Interstitial carbon related defects in low-temperature irradiated Si: FTIR and DLTS studies

The evolution of radiation-induced carbon-related defects in low temperature irradiated oxygen containing silicon has been studied by means of Fourier transform infrared absorption spectroscopy (FTIR) and deep level transient spectroscopy (DLTS). FTIR measurements have shown that annealing of interstitial carbon atom C-i, occurring in the temperature interval 260-300 K, results in a gradual appear

First results from the high resolution XUV undulator beamline BW3 at HASYLAB

Initial results from the XUV undulator beamline at the 4.5 GeV storage ring DORIS are reported. The beamline consists of three different undulators mounted on a revolver type device and a modified SX-700 plane grating monochromator with a spherical focusing mirror. It covers the spectral range from 50–2000 eV with excellent spectral resolution and high photon flux. In the energy range 400 eV to 1

Development of low affinity techniques for applications in clinical chemistry

Popular Abstract in Swedish I vår kropp pågår ständigt interaktioner mellan olika molekyler. Det är dessa interaktioner som styr hur vi mår och vad som händer i kroppen. Många av dessa interaktioner är svaga, vilket gör att det krävs många sådana interaktioner samtidigt för att uppnå effekt. Svaga interaktioner är snabba och reversibla, vilket betyder att kroppen snabbt kan anpassa sig efter nya fAn increase in the plasma level of creatine kinase MB (CKMB) has long been used to indicate acute myocardial infarction (AMI). For optimal treatment an early diagnosis is important. An increase in the ratio between the two isoforms of CKMB is seen much earlier than an increase in the total level of CKMB. One possible method for separating these isoforms could be weak affinity chromatography (WAC).

The CILO method: firm-supportive research approach enhancing enterprise performance

This paper describes a case of collaboration between academia and business firms in supporting innovation processes based on the CILO method, named after the CILO project (communication in learning organizations). The CILO method is an example of firm-supportive research approach. We describe the outcomes related to enhancing enterprise performance from applying the CILO-method in relation to one

Reliability test-retest of the Nordic Assisted Mobility Evaluation (NAME 1.0).

This paper describes preliminary results from the test-retest of the NAME 1.0. Four scales were tested: Mobility-related participation frequency; Mobility ease/difficulty; Mobility dependence; Extent of assistance in mobility. The test was conducted in the five Nordic countries. In all 147 mobility device users took part in the study, mean age 60 years (range 19 - 93). Each participant was intervi

Impact work-rate and wear of a loosely supported beam subject to harmonic excitation

Impact work-rate of a weakly damped beam with elastic two-sided amplitude constraints subject to harmonic excitation is calculated. Impact work-rate is the rate of energy dissipation to the impacting surfaces. The beam is clamped at one end and constrained by unilateral contact sites near the other end. This system was an object of a vibro-impact experiment which was analyzed in our earlier paper

Tilt anisoplanatism and PSF retrieval in LGS MCAO using a predictive controller

It is shown how tilt anisoplanatism in laser-supported multi-conjugatedadaptive optics (MCAO) systems can be a) predicted from a prioriknowledge, b) compensated using additional natural guide stars (NGS),and c) estimated in real time from control loop data to allow PSFretrieval. As a consequence of the problems associated with retrievingatmospheric tip and tilt from laser guide star (LGS) measurem