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In this review I will describe the advances that have recently been made in "traditional" two-dimensional gel based protein expression analysis. A major jump has been made toward the automation of gel image analysis and comparison, one of the major bottlenecks in the analysis chain as well as the automation of spot excision and preparation for mass spectrometric analysis. Currently the gel-based "
The LINC transmitter is an architecture that provides linear amplification using nonlinear but power efficient amplifiers. One crucial signal processing function of LINC is the signal component separator (SCS) which forms two constant-amplitude phase-modulated signals from the source signal. This paper presents an analog SCS chip implemented in a 0.35 mum CMOS process using a novel design based on
In humans, beta-alanine (BAL) and the neurotransmitter gamma-aminobutyrate (GABA) are transaminated by a single aminotransferase enzyme. Apparently, yeast originally also had a single enzyme, but the corresponding gene was duplicated in the Saccharomyces kluyveri lineage. SkUGA1 encodes a homologue of Saccharomyces cerevisiae GABA aminotransferase, and SkPYD4 encodes an enzyme involved in both BAL
Background Autism spectrum disorders (ASD) have been suggested to be overrepresented in anorexia nervosa. This study aimed to explore the comorbidity of ASD and other childhood onset neuropsychiatric disorders (COND) [attention-deficit/hyperactivity disorder (AD/HD) and tic disorders] in a group of severe eating disorder (ED) patients. Method Thirty female ED patients from a specialist hospital c
Here we present results from a field experiment in a sub-arctic wetland near Abisko, northern Sweden, where the permafrost is currently disintegrating with significant vegetation changes as a result. During one growing season we investigated the fluxes of CO2 and CH4 and how they were affected by ecosystem properties, i.e., composition of species that are currently expanding in the area (Carex rot
This article reports on a multiblock implementation of a general three-dimensional single-block computational fluid dynamics code, which is developed in a nonorthogonal, structured, collocated finite-volume grid system, and incorporates a range of turbulence models. The multiblock implementation is essentially block-unstructured, each block having its own local coordinate system unrelated to those
Transient wave propagation in a finite bi-isotropic slab is treated. The incident field impinges normally on the slab, which can be inhomogeneous wrt depth. Dispersion and bi-isotropy are modeled by time convolutions in the constitutive relations. Outside the slab the medium is assumed to be homogeneous, non-dispersive and isotropic, and such that there is no phase velocity mismatch at the boundar
The Sheinwoodian succession of Gotland comprises the Högklint, Tofta and Hangvar Formations and most of the Slite Group. The succession consists of hierarchically ordered shallow marine depositional cycles, produced by orbitally forced climate changes. During warmer and wetter intervals (climate maxima) more carbonate was produced than during the cooler and dryer climate minima. Higher carbonate p
A mathematical model is presented for calculating heat release rate in the Room Corner Test, where lining materials are mounted on both walls and ceiling. The model is based on a thermal theory for concurrent flow flame spread. By using a simple mathematical representation of the heat release rate from the Cone Calorimeter, analytical solutions are arrived at for the velocity and position of the p
Popular Abstract in Swedish Denna avhandling behandlar den process där man beräknar undervattensströmmar från ljud som reflekteras från en utsänd ljudpuls, precis som när en fladdermus bedömer omgivningen genom att lyssna på ekot. En ton skickas ut under en kort tid, och det Dopplerskift som uppkommer från rörliga föremål i vattnet kan sedan omsättas till vattenhastiget eller ström. Föremål som röThis thesis deals with the process of estimating underwater current from the backscattering signal transmitted from an ultrasonic transducer. The narrowband sinusoidal burst signal is Doppler-shifted due to the current, and this information is converted into current. The traditional mathematical model for this Doppler process is based on the assumption that the backscattering time signal is Gaussi
The COST/IWA benchmark simulation model has been available for seven years. Its primary purpose has been to create a platform for control strategy benchmarking of biological wastewater treatment processes. The fact that the benchmark has resulted in more than 100 publications, not only in Europe but also worldwide, demonstrates the interest for such a tool in the research community. In this paper,
Malaria parasites are a major cause of human mortality in tropical countries and a potential threat for wildlife, as witnessed by the malaria-induced extinction of naive Hawaiian avifauna. Identifying resistance mechanisms is therefore crucial both for human health and wildlife conservation. Patterns of malaria resistance are known to be highly polygenic in both humans and mice, with marked contri
A task-oriented system structure has been developed. In normal industrial robot programming, the path is created and the process is based on the path. Here a process-focused method is proposed, where a task can be split in subtasks, one for each part of the process with similar process-characteristics. By carefully encapsulating the information needed to execute a sub-task, this component can be r
This article reports on a parallel implementation of a general 3D multi-block CFD code. The parallelization is achieved by using three strategies. Firstly, it is done on dual-processor PC-clusters where Windows NT systems are running. A multi-thread programming model is adopted for the multi-block code, where one thread corresponds to a block. Shared memory is used for the exchange of inner-bounda
SelB is a bacterial elongation factor required for the decoding of a UGA stop codon together with a specific mRNA hairpin to selenocysteine. In attempts to crystallize Moorella thermoacetica SelB, a proteolysis process occurred and crystals of a proteolytic fragment were observed. The crystals, which appeared after a year, contained a C-terminal 30 kDa fragment containing the mRNA-binding domain.
A Discfilter with 10 and 18 mu m filter openings, respectively, was placed in parallel to a flotation plant for separation of biological flocs from a post-denitrifying Kaldnes Moving Bed (TM) Process, the last treatment step at the municipal wastewater treatment plant at Sjolunda, Malmo, Sweden. The effluent concentrations from the 10 and 18 mu m filter were 2-5 and 2-8 mg SS L-1, respectively, wh
Calcareous soils are frequently characterized by the low bioavailability of plant nutrients. Consequently, many vascular plant species are unable to successfully colonize calcareous sites and the floristic composition of calcareous and acid silicate soils has been shown to differ markedly. The root exudation of oxalate and citrate has been suggested to play a pivotal role in same nutrient acquisit
Objective: This paper analyzes some of the problems with error counting as well as the difficulty of proposing viable alternatives. Background: Counting and tabulating negatives (e.g., errors) are currently popular ways to measure and help improve safety in a variety of domains. They uphold an illusion of rationality and control but may offer neither real insight nor productive routes for improvin
