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Based on the Fenchel duality we build a primal-dual framework for minimizing a general functional consisting of a combined L1 and L2 data-fidelity term and a scalar or vectorial total variation regularisation term. The minimization is performed over the space of functions of bounded variations and appropriate discrete subspaces. We analyze the existence and uniqueness of solutions of the respectiv

BackgroundMisophonia is characterized by intense emotional reactions to specific sounds or visual stimuli and typically onsets during childhood. An obstacle for research and clinical practice is that no comprehensively evaluated measures for pediatric misophonia exist.MethodsIn a sample of 102 youth meeting the proposed diagnostic criteria of misophonia, we evaluated the child and parent-proxy ver

This paper proposes a ‘tool for thinking with’: that we can describe the interaction between people and computers, and especially people and developer tools, as a form of conversation. We outline this perspective, construct a work in progress analytical frame, and use it to talk about a couple of different examples and draw implications for future work.

The design of Sensory Substitution Devices (SSDs) often relies on the belief that the information supplied by the devices should allow the construction of spatial mental representations on the basis of which routes are planned. This study, in contrast, illustrates that navigation using an SSD can be conceived as an on-line, dynamic process, without the need for establishing a predefined plan or mo

Cluster-based programmes are used by regions across the globe as part of their industrial, innovation and development policies. They have become a key tool in smart specialisation strategies and are increasingly used to address social challenges. The contemporary popularity of cluster policies reflects the complexity of innovation and production processes, which places a premium on effective colla

Socialization plays an essential role in ensuring that newcomers to an organization enjoy greater productivity and also integrate well into their workgroups. Since the COVID-19 pandemic, enterprise social media (ESM) is increasingly being used in organizations as an informal socialization tool. However, the effectiveness of these tools in affording the necessary socialization opportunities and ena

Introduction: The European Working Group on Sarcopenia in Older People (EWGSOP) published a revised definition of sarcopenia in 2018. There are few incidence studies of sarcopenia following the latest definition. Objective: To study prevalence, incidence proportion and incidence rate of sarcopenia in a simple random sample of older Swedish men using the EWGSOP2 definition. Methods: Men aged 69-81

Background Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study was to investigate the efficacy of ICBT for OCD in a randomized controlled trial

Aims: The aim of this study was to investigate associations between having visited the theatre/cinema and an arts exhibition during the past year and all-cause, cardiovascular disease (CVD), cancer and other-cause mortality. Methods: The 2008 public health postal survey in Scania, Sweden, was distributed to a stratified random sample of the adult population (18–80 years old). The participation rat

Reducing the heterogeneity of technical lignin is essential to obtain predictable and high-performance polymeric materials that are suitable for high-value applications. Organic solvents with different polarities and solubilities can be used to fractionate lignin and reduce the complexity and diversity of its chemical structure. Among the various solvents and solvent mixtures, acetone-water mixtur

Stupidity is generally thought of as a hindrance to learning: an epistemic vice that stands in the way of knowledge and understanding. In this article, I challenge this idea by exploring some of the meanings of stupidity that place it in a positive relation to learning. In this light, the article discusses two notions of stupidity: stupidity as unfinished thought and stupefaction through study. I

ObjectiveTo determine the feasibility of a digitally automated population-based programme for organised prostate cancer testing (OPT) in Southern Sweden.Patients and MethodsA pilot project for a regional OPT was conducted between September 2020 and February 2021, inviting 999 randomly selected men aged 50, 56, or 62 years (y). Risk stratification was based on PSA, PSA density (PSAD), and biparamet

BackgroundPyogenic liver abscess (PLA) is a rare entity that is associated with substantial mortality and morbidity. Our objective was to investigate variables associated with mortality and subsequent PLA in patients diagnosed with PLA in southern Sweden.MethodsWe conducted a population-based observational study comprising all episodes of PLA that occurred between 2011 and 2020 in the county of Sk

BACKGROUND: Technological developments such as Virtual reality (VR) provide new opportunities to extend and innovate mental healthcare. VR as a tool for clinical assessment has been described as promising, as it can enable real-time assessment within real-like environments or contexts as opposed to self-report and behavioral tasks in laboratory settings.OBJECTIVE: With this systematic review we ai

BACKGROUND: Electronic health records (EHRs) are generated at an ever-increasing rate. EHR trajectories, the temporal aspect of health records, facilitate predicting patients' future health-related risks. It enables healthcare systems to increase the quality of care through early identification and primary prevention. Deep learning techniques have shown great capacity for analyzing complex data an

The novel promoter system iodine monochloride/silver trifluoromethanesulfonate (ICl/AgOTf) was evaluated with various thioglycoside donors and saccharide acceptors, and O-glycosides were obtained in 46−82% yield. Several practical advantages of the ICl/AgOTf system over known promoter systems were observed, such as convenient handling of the reagents and absence of byproducts related to N-succinim