T-Cell Prolymphocytic Leukemia
This chapter summarizes current knowledge and diagnostic criteria for T-cell prolymphocytic leukemia (T-PLL). T-PLL is an aggressive disease characterized by a proliferation of small to medium-sized lymphocytes with a postthymic phenotype usually involving the blood, bone marrow, lymph nodes, spleen, and skin. The leukemic cells are usually positive for CD2, CD3 CD5, CD7, CD43, CD52, and CD26, but
