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BACKGROUND: Early glottic cancer can be treated with laser resection or radiotherapy. In an earlier study, we found that voice function after laser resection was inferior to that after radiotherapy.OBJECTIVES: This study was designed to determine if reduced margins at laser resection improved voice function without impairing oncologic results.METHOD: A total of 268 patients with previously untreat
BACKGROUND: A previous study on mechanical complications after central venous catheterisation demonstrated differences in complication rates between male and female operators. The objective of this subgroup analysis was to further investigate these differences. The hypothesis was that differences in distribution of predefined variables between operator genders could be identified.METHODS: This was
Background and ObjectivesKilning is crucial in oat processing, to prevent rancidity and extend shelf-life. This study examines kilning effects on the macronutrient composition in Swedish oat varieties Galant, Fatima, and Belinda. We compared two kilning methods: one mimicking industrial practice and a simplified version. We analyzed dietary fibers (arabinoxylan, β-glucan), protein and amino acids,
“Astrobiology as science” refers to how astrobiology is characterized and discussed in the philosophy of science.
Peripheral T cell lymphomas are typically aggressive with a poor prognosis. Unlike other hematologic malignancies, the lack of target antigens to discriminate healthy from malignant cells limits the efficacy of immunotherapeutic approaches. The T cell receptor expresses one of two highly homologous chains [T cell receptor β-chain constant (TRBC) domains 1 and 2] in a mutually exclusive manner, mak
OPINION He refuses to enter into the collective wage agreements that define the West’s most corporatist economy.
During the 18th century, collections of coins and medals were familiar sights. The collectors ranged from scholars to amateurs, men and women and the collectables tempted collectors for various reasons: they signified wealth and knowledge, they rendered historical events or current politics in material form, or they were miniature artworks and financial investments. Also, the visual and material c
Artikeln argumenterar för en förnyad relevansen för tidsgeografi iturism i ljuset av mobil teknikanvändning och allestädes närvarandedigital uppkoppling. Uppsatsen föreslår begreppet fygitalitet för attförstå hur digital teknik används i det fysiska rummet, ochhur samspelet mellan det fysiska och det digitala omformasi turisters projekt, rutter, kopplingar och begränsningar. Det teoretiskabidragetThe paper argues for the renewed relevance of time geography in tourism in light of the use of mobile technologies and ubiquitous connectivity. The paper proposes the concept of phygitality to understand how digital technologies are used in physical space, and how the interaction between the physical and the digital reconfigures tourists’ projects, paths, bundles, and constraints. The theoretical
In this article some initial results from the projects "Bronsildems deglar" (en. "Bronze Age melting crucibles") and "Deglarna frin Bokenäs" (en. "The crucibles from Bokenäs") are presented. The aim of the projects is to expand our knowledge of the production, use and discard of technical ceramics in south Sweden using laboratory analysis. This article describes the results and conclusions made bIn this article some initial results from the projects "Bronsildems deglar" (en. "Bronze Age melting crucibles") and "Deglarna frin Bokenäs" (en. "The crucibles from Bokenäs") are presented. The aim of the projects is to expand our knowledge of the production, use and discard of technical ceramics in south Sweden using laboratory analysis. This article describes the results and conclusions made b
This research tests whether self-labelling with a derogatory or reclaimed label is perceived as an act of reclamation. A pilot study (N = 102) identified English terms used to label lesbian women and gay men. The main study (N = 276) used a between-groups vignette design in which participants read about a woman/man self-labelling with a descriptive (lesbian/gay), reclaimed (queer), or derogatory g
This paper focuses on Bronze Age melting crucibles in southern Scandinavia. The shape and purpose of the crucibles have long been known, but the process of making one has not been studied thoroughly. The crucibles have in some cases been reconstructed in order to replicate the casting process or the finished product, but have rarely been the main subject of research. In this paper crucibles found
Eutrophication and brownification are ongoing environmental problems affecting aquatic ecosystems. Due to anthropogenic changes, increasing amounts of organic and inorganic compounds are entering aquatic systems from surrounding catchment areas, increasing both nutrients, total organic carbon (TOC), and water color with societal, as well as ecological consequences. Several studies have focused on
Patients with Wilms tumor (WT) in general have excellent survival, but the prognosis of patients belonging to the subgroup of WT with diffuse anaplasia (DA) is poor due to frequent resistance to chemotherapy. We hypothesized that DA WT cells might undergo changes, such as acquiring a persistent tolerance to DNA damage and copy number aberrations (CNAs), which could eventually lead to their resista
Background: Tuberculosis (TB) disease has been associated with pregnancy complications. However, the potential impact of TB infection (TBI) on pregnancy outcome is unknown. To investigate this, we conducted a register-based study in immigrant women screened with QuantiFERON assays for TBI in antenatal care in Sweden. Methods: Women with history of immigration from TB-endemic countries were eligibl
Background: In Sweden, information on seroprevalence of tick-borne encephalitis virus (TBEV) in the population, including vaccination coverage and infection, is scattered. This is largely due to the absence of a national tick-borne encephalitis (TBE) vaccination registry, scarcity of previous serological studies and use of serological methods not distinguishing between antibodies induced by vaccin
Background: There is little agreement on clinically useful criteria for identifying real-world responders to biologic treatments for asthma. Objective: To investigate the impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in adults with severe asthma. Methods: This was a longitudinal, cohort study across 22 countries participating in the International Sever
Cooperative transport allows for the transportation of items too large for the capacity of a single individual. Beyond humans, it is regularly employed by ants and social spiders where two or more individuals, with more or less coordinated movements, transport food to a known destination. In contrast to this, pairs of male and female dung beetles successfully transport brood balls to a location un
Leveraging the potential of machine learning and recognizing the broad applications of binary classification, it becomes essential to develop platforms that are not only powerful but also transparent, interpretable, and user friendly. We introduce alphaML, a user-friendly platform that provides clear, legible, explainable, transparent, and elucidative (CLETE) binary classification models with comp
