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Introduction: This study evaluated real-world cassette use and cost of levodopa-carbidopa intestinal gel (LCIG; 2000 mg levodopa equivalent dose [LED]) and levodopa-entacapone-carbidopa intestinal gel (LECIG; 1250 mg LED) pump treatments among patients with advanced Parkinson’s disease (PD) in Sweden. Methods: This was a non-interventional, longitudinal, retrospective, comparative study of patient

Abstract: Diffusion-weighted imaging (DWI) offers critical insights into tissue microstructure through the assessment of water molecule random displacements and plays a central role in the assessment of neoplastic and non-neoplastic diseases. To successfully implement and use DWI in clinical practice, guidelines for acquisition, interpretation of image contrast and of artefacts should be followed,

We consider analogues of Grigorchuk-Gupta-Sidki (GGS-)groups acting on trees of growing degree; the so-called growing GGS-groups. These groups are not just infinite and do not possess the congruence subgroup property, but many of them are branch and have the p-congruence subgroup property, for a prime p. Among them, we find groups with maximal subgroups only of finite index, and with infinitely ma

When searching for an object in my pocket, I can clearly perceive the edges, shape, and hardness of the items I touch — regardless of which part of my fingers makes contact and despite large sensorimotor noise. What accounts for these perceptual invariants? Vincent Hayward introduced key elements to investigate this question, by (i) analyzing mechanical spatiotemporal invariants emerging from the

Listeners rapidly form trait impressions from voices, inferring multiple person characteristics within milliseconds. We employed a novel method, Self-Steered Sound Synthesis (S4), to identify and compare the acoustic signatures underlying these impressions. Participants interactively used S4 to synthesise voices expressing six person characteristics - age, masculinity, health, attractiveness, domi

Much scholarship has critiqued the fact that non-governmental organisations (NGOs), as a result of global neoliberalism and consequential state retreat, have become private service providers of children’s protection rights. But how can we explain the situation when neoliberal states also undergo autocratisation and take back service provision from NGOs, while at the same time preserving the privat

A vacuum-free, high-throughput synthesis of indium tin oxide (ITO) via Combustion Oxidation with Rapid Plasma Processing (CORP) utilizes a solution-based exothermic combustion reaction to generate the oxide with tunable control of either amorphous or crystalline phases. A subsequent open-air, forming gas plasma treatment is used to introduce oxygen vacancies and promote crystallization. The evolut

This thesis researches a perceived paradox between the Swedish government's reluctance to identify their foreign policy as feminist, and the simultaneous production of an inclusion plan that implements feminist and queer perspectives. The application of a feminist perspective on Fairclough's three-dimensional model of Critical Discourse Analysis aims to investigate how nationalist and femi

We study large n expansions for the partition function of a Coulomb gas (Formula presented.) where Q is a radially symmetric confining potential on the complex plane C. The droplet is not assumed to be connected, but may consist of a number of disjoint annuli and possibly a central disk. The boundary condition is “soft edge”, i.e., Q is smooth in a C-neighbourhood of the droplet. We include the fo

This editorial introduces the Special Section on 'The Borders Within: Socio-Economic Rights and Non-discrimination in EU Law' whose purpose is to provide a comprehensive and non-fragmented understanding of socio-economic rights, the right to non-discrimination and their meaning for welfare in EU Member States. Under EU law the boundaries between national socio-economic policies and the enjoyment o

Abstract: Background: Shiga toxin producing Escherichia coli (STEC) inducing hemolytic uremic syndrome (HUS) with multiple organ involvement is associated with significant morbidity and mortality. The treatment has mostly been focused on kidney, respiratory and cardiovascular supports and not against the bacteria that cause STEC-HUS. The use of bactericidal therapy has been shown to be antibiotic Background: Shiga toxin producing Escherichia coli (STEC) inducing hemolytic uremic syndrome (HUS) with multiple organ involvement is associated with significant morbidity and mortality. The treatment has mostly been focused on kidney, respiratory and cardiovascular supports and not against the bacteria that cause STEC-HUS. The use of bactericidal therapy has been shown to be antibiotic dependent

Paper om den svensk-judiske historikern Hugo Valentin och dennes texter om förintelsen från tidigt 1940-tal till tidigt 1960-tal.

AbstractBackground: The pathophysiological mechanisms underlying single-stranded RNA (ssRNA) virus infections have been investigated extensively and at an accelerated pace in recent years, largely driven by the COVID-19 pandemic. Particular attention has been given to their potential roles in respiratory insufficiency, endothelial dysfunction, thrombosis, and inflammatory responses within the centBackground: The pathophysiological mechanisms underlying single-stranded RNA (ssRNA) virus infections have been investigated extensivelyand at an accelerated pace in recent years, largely driven by the COVID-19 pandemic. Particular attention has been given to their potential rolesin respiratory insufficiency, endothelial dysfunction, thrombosis, and inflammatory responses within the central nervou

AbstractBackground: The pathophysiological mechanisms underlying single-stranded RNA (ssRNA) virus infections have been investigated extensively and at an accelerated pace in recent years, largely driven by the COVID-19 pandemic. Particular attention has been given to their potential roles in respiratory insufficiency, endothelial dysfunction, thrombosis, and inflammatory responses within the centBackground: The pathophysiological mechanisms underlying single-stranded RNA (ssRNA) virus infections have been investigated extensivelyand at an accelerated pace in recent years, largely driven by the COVID-19 pandemic. Particular attention has been given to their potential rolesin respiratory insufficiency, endothelial dysfunction, thrombosis, and inflammatory responses within the central nervou

This chapter examines the experiences of children in the Holocaust in various geographic contexts. It raises questions about the avenues for rescue and survival of children and the limits of children’s agency. How did gender, age, and family background play a role? And how did children adjust to or resist their new - and supposedly temporary - separation from their families?.

This article analyzes the effects of self-balancing in multiactive bridge converters. Therefore, it proposes a time-domain approach to model the dynamics of multiwinding transformer-based multilevel dc/dc converter, including self-balancing. In previous research, multiwinding transformers have been modeled using average-based power transfer models. These models, while simple, have no direct intuit

Chronic obstructive pulmonary disease (COPD) and lung cancer (LC) are recognized as severe diseases of the lungs and are closely linked to cigarette smoking and environmental pollution and share common mechanisms such as oxidative stress, inflammation, matrix degradation, and airway remodeling. Epidermal growth factor receptor (EGFR), a transmembrane receptor featuring an extracellular ligand bind

Traumatic brain injury (TBI) leads to intracerebral inflammation involving resident microglial cells and astrocytes as well as invading peripheral dendritic cells (DCs), monocytes, and neutrophils. However, the profile of immune blood cells activated by TBI remains poorly defined. Several animal models showing invasion of circulating classical dendritic cells type 2 (cDC2s) to the traumatically in

ObjectivesThis study investigates the impact of transitioning from restricted to 24/7 access to blood culture cabinets on blood culture processing.MethodA post-hoc retrospective study and a prospective laboratory simulation to evaluate the effects of delayed incubation were conducted. Data analysis evaluated clinical data comparing incubation-to-detection (ITD) and Collection-to-detection (CTD) in