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Introduction: Antibodies targeting the blood-stage of Plasmodium falciparum play a critical role in naturally acquired immunity to malaria by limiting blood-stage parasitemia. One mode of action of antibodies is the direct inhibition of merozoite invasion of erythrocytes through targeting invasion ligands. However, evasion of inhibitory antibodies may be mediated in P. falciparum by switching betw
Introduction: Impulse control and related behavioral disorders (ICBDs) commonly complicate Parkinson’s disease (PD) course. The ICBDs spectrum encompasses two groups of conditions, with distinct pathophysiology: proper ‘impulse control disorders (ICDs)’ (e.g. gambling) and the ‘ICDs related disorders (ICDs-RD)’ (e.g. punding). Behavioral disturbances are associated with dopamine replacement therap
Background: The optimal timing of anticoagulation for patients with acute ischaemic stoke with atrial fibrillation is uncertain. We investigated the efficacy and safety of early compared with delayed initiation of direct oral anticoagulants (DOACs) in patients with acute ischaemic stroke associated with atrial fibrillation. Methods: We performed a multicentre, open-label, blinded-endpoint, paralle
Critical urbanists’ placement of smart city initiatives in Western Europe or North merica mostly on “low” rungs of participatory ladders or scaffolds does not mean that smart urban development connotes democracy-eroding neoliberalization everywhere. This article offers a more globally variegated and dynamic understanding of the relationship between citizens and smart cities. We apply an institutio
Surveys in the Milky Way and Large Magellanic Cloud have revealed that the majority of massive stars will interact with companions during their lives. However, knowledge of the binary properties of massive stars at low metallicity, and therefore in conditions approaching those of the Early Universe, remain sparse. We present the Binarity at LOw Metallicity (BLOeM) campaign, an ESO large programme
Currently, most research and public datasets for video sports analytics are base on detecting players as bounding boxes in broadcast videos. Going from there to precise locations on the pitch is however hard. Modern solutions are making dedicated static cameras covering the entire pitch more readily accessible, and they are now used more and more even in lower tiers. To promote research that can t
Among small birds the great tit Parus major stands out as especially good at performing various cognitive tasks that are impressive to humans. It may, for example, knock on kitchen windows to get bird feeder refills, drum on beehives in winter to lure the bees to come walking out, perch in flowering fruit trees and kill incoming bumblebee queens and large butterflies, give false alarm calls in ord
Sweden's feminist foreign policy (FUP), which was pursued between 2014 and 2022, involved a more strategic anchoring and communication of the country's state feminist tradition and commitment to justice in world politics. The emphasis on gender equality as the basis for foreign policy was largely based on the UN's agenda for women, peace, and security (WPS). Digital diplomacy and social media, whi
This study investigates strategies for igniting hydrogen in compression ignition engines, a process traditionally hindered by hydrogen’s high ignition temperature. In conventional dual-fuel engines, a small diesel pilot is often used to ignite hydrogen, taking advantage of diesel’s lower ignition temperature to initiate combustion. While effective, this approach introduces carbon emissions, limiti
Aim: To explore the possibility of reducing the diagnostic burden in children with prenatally detected unilateral ureteropelvic junction obstruction. Methods: Children with unilateral ureteropelvic junction obstruction (2012–2020) were identified from a prenatal hydronephrosis registry. The frequency of adverse events, predictors for event-free follow-up beyond 1 year of age, and examination burde
The first measurement of the multiplicity dependence of intra-jet properties of leading charged-particle jets in proton–proton (pp) collisions is reported. The mean charged-particle multiplicity and jet fragmentation distributions are measured in minimum-bias and high-multiplicity pp collisions at center-of-mass energy s = 13 TeV using the ALICE detector. Jets are reconstructed from charged partic
Background: Cardiac surgery carries a heightened risk of bradyarrhythmias, but current permanent pacemaker (PPM) implantation estimates rely on non-contemporary studies. This study primarily aimed to explore the incidence and indications for PPM implantation at 30 days and 1 year after different cardiac surgical procedures in a modern cohort. Secondary outcomes were PPM incidence at 10 years and t
Purpose: To introduce a newly developed digital platform and compare its reliability and agreement with paper-based questionnaires for assessing quality of vision before and after cataract surgery. Setting: University-affiliated ophthalmology department and private clinic. Design: Prospective, randomized trial with parallel design of 1:1 allocation ratio without masking. Methods: Between 11/2021 a
The pT-differential production cross sections of non-prompt D0, D+, and Ds+ mesons originating from beauty-hadron decays are measured in proton–proton collisions at a centre-of-mass energy s = 13 TeV. The measurements are performed at midrapidity, |y| < 0.5, with the data sample collected by ALICE from 2016 to 2018. The results are in agreement with predictions from several perturbative QCD calcul
Aim: Our primary aim was to assess how dispersal limitation affected forest changes in the Northern Hemisphere during the last glacial cycle, and especially after the last deglaciation. Location: Northern Hemisphere (between 20°N and 80°N). Time Period: 50,000–0 years before present. Major Taxa Studied: Angiosperms and gymnosperms. Methods: We used the LPJ-GM 2.0 dynamic global vegetation model to
Recent estimates point to dramatic increases in private capital flowing to biodiversity. Examining main sources of this increase — equity investments and debt — this review asks how biodiversity finance is being calculated, and whether private capital flowing to biodiversity action is growing as much as reported. Furthermore, by examining the literature on the standards and metrics, we ask whether
Pollinators are estimated to benefit the reproduction of three-quarters of global leading crop species and contribute to 3%–8% of the total global food production. Ongoing declines in pollinator populations have raised concerns about repercussions for food security. Thus, there is a need to better understand how agricultural yields depend on pollinator abundance. Here, we established yield–pollina
While the future and temporality have received increased attention in economic geography in recent years, there is a need for further understanding of how this creates opportunities and challenges for our methods. Based on our independent research on environmental markets, this paper discusses the methodological challenge of studying markets-in-the-making while taking the force of the future serio
