Filtyp
Interdisciplinary research and education on human-environment relations has a natural place in many Anglo-American geography and anthropology departments. In Sweden, however, critical scholarship across the socio-natural divide has largely been outsourced to the interdisciplinary field of human ecology. Since the 1970s, Swedish human ecologists have sought to integrate perspectives from the social
BACKGROUND AND AIM: Warming temperature promotes bacterial growth while extreme precipitation enhances fecal-oral route of exposures to these pathogens, particularly in resource limited settings, increasing burden of diarrheal diseases. Given climate change related increases in frequency of extreme events, there is a pressing need to develop meaningful early warning system with adequate lead time
BACKGROUND: ATOR-1017 (evunzekibart) is a human agonistic immunoglobulin G4 antibody targeting the costimulatory receptor 4-1BB (CD137). ATOR-1017 activates T cells and natural killer cells in the tumor environment, leading to immune-mediated tumor cell death.METHODS: In this first-in-human, multicenter, phase I study, ATOR-1017 was administered intravenously every 21 days as a monotherapy to pati
CD40-stimulating immunotherapy can elicit potent anti-tumor responses by activating dendritic cells and enhancing T-cell priming. Tumor vessels orchestrate T-cell recruitment during immune response, but the effect of CD40-stimulating immunotherapy on tumor endothelial cells has not been evaluated. Here, we have investigated how tumor endothelial cells transcriptionally respond to CD40-stimulating
Agonistic CD40 antibodies activate dendritic cells and can expand and activate tumor-specific T cells. Our purpose was to assess the CD40 agonistic antibody ADC-1013 in the clinical setting including intratumoral administration since preclinical studies have indicated that intratumoral is better than intravenous administration. A Phase I, open label, multicenter study was conducted in patients wit
Background: The CTLA-4 blocking antibody ipilimumab has demonstrated substantial and durable effects in patients with melanoma. While CTLA-4 therapy, both as monotherapy and in combination with PD-1 targeting therapies, has great potential in many indications, the toxicities of the current treatment regimens may limit their use. Thus, there is a medical need for new CT
Fruit juices are widely consumed due to their affordability, nutritional value, and convenience. As global health consciousness rises, the fruit juice market is projected to grow from $153.17 billion in 2024 to $209.51 billion by 2029. Membrane processes, first introduced in the 1970s, have become essential in juice production, offering precise separation at low temperatures. The fruit juice indus
Uppslagsord: mellankrigstiden i Nationalencyklopedin.
Uppslagsord: Waffen-SS i Nationalencyklopedin
Uppslagsord under "Historia", historia som skolämne i Nationalencyklopedin.
Uppslagsord: Lima i Nationalencyklopedin.
Uppslagsord: Raoul Wallenberg i Nationalencyklopedin.
Uppslagsord: Berlinkonferensen i Nationalencyklopedin.
Uppslagsord: Raphael Lemkin i Nationalencyklopedin.
Uppslagsord: historiebruk i Nationalencyklopedin.
Background: The Swedish housing stock generally maintains a high standard. However, earlier policies prioritized quantity and rapid housing production targeting a younger population, over policies that require accessible housing design. With an aging population, evidence-based policies supporting ageing in place while managing societal costs are crucial. This thesis aimed to increase the knowledge
