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In past human populations, atherosclerosis has been identified in mummies from different regions of the world, and from a range of chronological periods (for extensive reviews see Chapters 3 and 4). This current study from Sweden aims to contribute to the limited evidence for atherosclerosis associated with human skeletal remains by presenting examples of atherosclerosis in another part of the bod
In this paper, a factor-augmented version of the New Keynesian Phillips curve (NKPC) is assessed using a data set comprised of a large panel of European Union (EU) member countries. The factor-augmentation is natural given that country-level inflation rates are highly co-moving. The presence of unattended common factors is important because it raises the issue of omitted variables bias, as the rea
Addressing the need for modulated spin configurations is crucial, as they serve as the foundational building blocks for next-generation spintronics, particularly in atomically thin structures and at room temperature. In this work, we realize intrinsic ferromagnetism in monolayer flakes and tunable ferro-/antiferromagnetism in (Fe0.56Co0.44)5GeTe2 antiferromagnets. Remarkably, the ferromagnetic ord
Objective. Non-neuronal acetylcholine (ACh) has been suggested to be a mediator for the development of various types of cancer. We analyzed a possible role for this molecule in carcinogenesis and/or progression of human colon cancer, in patient biopsies harvested from the colon during surgery. We addressed whether ACh synthesis (by choline acetyltransferase) and/or degradation (by ACh esterase), a
We used immunochemistry to demonstrate expression of acetylcholine's nicotinic α7-receptor subtype in human colon cancer cell line HT-29. Moreover, RT-PCR and immunochemistry showed that choline acetyltransferase and acetylcholine esterase, the enzymes responsible for acetylcholine synthesis and degradation, respectively, localise in HT-29 cells. Bromoacetylcholine bromide, an inhibitor of choline
Changing climatic conditions is a perpetual circumstance for mankind. In this study, we investigate local environmental and climatic changes near Kangerlussuaq, west Greenland. Our reconstruction is based on a lake sediment core and methods include chemical proxies and a palynological analysis. The investigated site is located 15 km from the Aasivissuit Inuit summer hunting ground, which has been
Objectives To assess the long-term effects on weight reduction and health of a group-based behavioral weight intervention over six months focusing eating for fulfillment as compared to a control regime with brief intervention. Method Overweight or obese adults (n = 176, 80% female, mean BMI 33.8 ± 4.7 kg/m2, mean age 55.2 ±10.1 years) were randomized to a group treatment or control receiving a bri
Protein aggregation is a key process in the development of many neurodegenerative disorders, including dementias such as Alzheimer's disease. Significant progress has been made in understanding the molecular mechanisms of aggregate formation in pure buffer systems, much of which was enabled by the development of integrated rate laws that allowed for mechanistic analysis of aggregation kinetics. Ho
Heavy metal contamination poses a significant threat to soil quality, plant growth, and food safety, and directly affects multiple UN SDGs. Addressing this issue and offering a remediation solution are vital for human health. One effective approach for immobilizing heavy metals involves impregnating cypress chips with calcium hydroxide (Ca(OH) 2) to enhance the chemical adsorption capacity of the
The assemblage of pottery from Studentholmen, excavated by Knut Stjerna in 1907, contains one of the largest and most varied collections of medieval ledglazed redwares from the medieval town of Uppsala. Previous have pointed to the similarities in form and technology with the larger productions centers in western Europe as well as to the possibilities that some of the less elaborately decorated pi
Anthropogenic changes to the environment expose wildlife to many pollutants. Among these, tropospheric ozone is of global concern and a highly potent pro-oxidant. In addition, human activities include several other implications for wildlife, e.g., changed food availability and changed distribution of pathogens in cities. These co-occurring habitat changes may interact, thereby modulating the physi
More likely a distaff than a wand The leading interpretation of five iron staffs with expanded basket handles found in women’s graves from the Viking era, including “Klintastaven”, are that they are staffs or wands of a type of Viking seeresses, völvas. This text challenges that interpretation and argues that they should be interpreted as distaffs instead. The support for the staffs being used by
Background: Road transportation is one of the main sources of CO2 emissions. Making logistics more efficient, e.g., through co-loading freight transport, would reduce emissions. However, this requires the sharing of freight and routing data between actors in the logistics chain. Aim: This study aims to explore the literature on how Open Data Ecosystems (ODEs) can be applied to the logistics sector
