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With the prevalence of obesity, metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common chronic liver disease worldwide and can cause a series of serious complications. The pathogenesis of MASLD is complex, characterized by oxidative stress, impaired mitochondrial function and lipid metabolism, and cellular inflammation. Mitochondrial biology and function are ce

Despite limitations like poor mimicry of the human cell microenvironment, contamination risks, and batch-to-batch variation, cell culture media with animal-derived components such as fetal bovine serum (FBS) have been used in vitro for decades. Moreover, a few reports have used animal-product-free media in advanced high throughput three-dimensional (3D) models that closely mimic in vivo conditions

This thesis examines moral advice as a distinctive speech act, focusing on its aim in guiding deliberation. Despite its prevalence in moral discourse, moral advice has been overlooked in comparison to other speech acts, such as blame, praise, and promise. Drawing on speech act theory, I categorise moral advice as a directive speech act, and argue that it is best understood as a hearer-first direct

Purpose: To determine the frequency and accuracy of pseudoexfoliation syndrome (PEX) assessment in referrals from primary care optometrists before the new Swedish glaucoma guidelines were established, and to evaluate an optometrist’s ability to assess PEX. Patients and Methods: We studied PEX assessments in 95 referrals (95 patients,189 eyes) with elevated intraocular pressure (IOP) from optometri

Objectives To determine the incidence rate (IR) and predictors of myocardial infarction (MI) in patients with antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) as well as to estimate the IR ratio (IRR) of MI in AAV versus the background population. Methods 325 patients diagnosed with AAV 1997-2016 in Skåne, Sweden were included. Data were collected from the time of AAV dia

Outbreaks of highly pathogenic avian influenza (HPAI) have intensified over the last decade, spotlighting the concept of “epicentre” as a means of locating disease origins. Although epicentre thinking can facilitate rapid interventions, it often overlooks the political-economic and ecological forces driving outbreaks. Drawing on critical geography, political ecology, and global supply chain analys

A search is reported for long-lived dark photons with masses between 0.1 GeV and 15 GeV, from exotic decays of Higgs bosons produced via vector-boson-fusion. Events that contain displaced collimated Standard Model fermions reconstructed in the calorimeter or muon spectrometer are probed. This search uses the full LHC Run 2 (2015–2018) data sample collected in proton–proton collisions at s=13 TeV,

Global climate change is characterized by increasing and differentiated exposure to climate-related hazards such as floods, landslides, avalanches, storms, and wildfires (IPCC 2018, 2022). There is a significant volume of research on the effects of such events, and over the last decade, much of this research has been directed at where most lives and values can be saved by protective measures (e.g.

Background: Access to safe and reliable water and sanitation remains a critical public health and development challenge, with rural and low-income communities being disproportionately affected by inadequate services and heightened exposure to waterborne diseases. Despite global efforts and infrastructure-based progress indicators, significant disparities persist, and these often overlook users’ pe

Nitrate nitrogen contamination of groundwater is often related to agricultural production and is a common problem in many parts of the world, particularly in regions that depend on groundwater for water supply. Nitrate nitrogen concentrations in groundwater in the Kumamoto area have increased in recent years, and countermeasures are urgently needed. Identifying the causes and sources of contaminat

Dizziness and vertigo affect up to 20% of adults annually. Cervicogenic dizziness (CGD), a debated clinical entity, is characterized by dizziness associated with cervical pain or dysfunction, stemming from altered proprioceptive input from the cervical spine. Despite its recognition in clinical practice, CGD remains controversial due to its reliance on exclusionary diagnosis and the absence of spe

Introduction Common complications after surgical procedures include surgical site infection, wound rupture and incisional hernia. Wound healing can be influenced by the technique for abdominal access and closure. A Suture-Length to Wound-Length (SL/WLr) ratio ≥ 4 is advised to achieve a high-quality wound closure. This thesis describes the background and clinical realities of abdominal wall relate

This thesis approaches the moral responsibility debate from the “victim’s perspective,” a perspective that is often neglected in the literature. My aim is to show that by taking the victim’s perspective, philosophical discussions can gain a more spherical if not, complete picture of responsibility practices. The thesis explores the implications of adopting or excluding certain perspectives in phil

Victim blaming is a harmful but quite pervasive phenomenon occurring in contemporary societies. When people engage in victim blaming, they shift the burden of the harmful act from the perpetrators and place it upon the victims instead. This article explores how the discourse on moral responsibility can help make sense of victim blaming. The distinction between moral responsibility and blameworthin

This article presents a conversation with Dr. Ioannis Kampourakis, Associate Professor of Law and Markets at Erasmus University Rotterdam, as part of Lund University’s Screening for Sustainability project. Kampourakis’ research explores the political economy of the green transition, focusing on how markets can be deliberately designed and steered—what he calls ‘market instrumentalism’—to achieve s

The Area of Freedom, Security and Justice (AFSJ), established by the Treaty of Lisbon under Article 3(2) TEU and regulated under Title V of the TFEU, is increasingly occupying a central place in the case law of the Court of Justice of the EU (CJEU). The former Vice-President of the Court, Judge Lars Bay Larsen, has played a key role in the development of the relevant case law, having acted as judg

From 2015 onwards almost every EU migration policy document has the professed objective of shaping a ‘fair, efficient, and sustainable’ migration. But what would a sustainable migration look like in terms of legal design? By focusing on the EU legal order, the article provides an answer to this question. Specifically, the article presents the findings of a critical historical study of different ar

This edited volume aims to enrich the study of the Court of Justice of the EU by providing normative—as opposed to descriptive—assessments of its legal reasoning. Taking as a starting point a descriptive account of the Court’s adjudicative practice, which informs a shared conceptual basis from which the various contributions move, the volume offers a diverse collection of normative assessments of