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Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic susceptibility has not been performed. To identify novel and pleotropic SqCC risk variants, we performed a meta-analysis of GWAS data on lung SqCC (LuSqCC), oro/pharyngeal SqC
Background: Prognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of intensive care could produce a reliable model for
We have successfully fabricated high quality single crystalline La0.7Sr0.3MnO3 (LSMO) film in the freestanding form that can be transferred onto silicon wafer and copper mesh support. Using soft x-ray absorption (XAS) and resonant inelastic x-ray scattering (RIXS) spectroscopy in transmission and reflection geometries, we demonstrate that the x-ray emission from Mn 3s-2p core-to-core transition (3
Multiferroic materials have shown significant potential for next generation nanoelectronic and multifunctional devices due to their coexistent order parameters and versatile tunabilities. Nevertheless, the selectivity of the room temperature multiferroics is extremely limited. In this manner, single-phase solid-solution-type multiferroics that are composed by distinct oxides exhibiting either ferr
Clinical implementation of anti-stromal therapies in pancreatic cancer has been delayed by unanticipated tumor-restraining properties of the desmoplastic stroma. In confronting these challenges, Chen et al. demonstrate in this issue of Cancer Cell that fibroblast-specific deletion of collagen I, in the background of oncogenic Kras-induced spontaneous murine pancreatic ductal adenocarcinoma, enhanc
Species diversity and composition of the Coleoptera (beetle) fauna in a recently abandoned military exercise field in south Sweden was studied during sixteen years. The sixteen square km large area contained deciduous wood (mainly Fagus and Carpinus), shrubland, open ground, and pastures. Beetles were captured using three different methods: pitfall trapping, striking of foliage, and sweep bag coll
The topic of this article is experiences regarding Supplemental Instruction (SI) at two Scandinavian Universities. The purpose is to describe the basis for and implementation of SI programmes at the two universities, and to compare their similarities and differences. Our research questions were as follow: What were the reasons and background for implementing SI? How was the SI programme founded, p
The present survey study focuses on potential benefits of the SI-PASS experience for former Leaders in their professional life after graduating from higher education. This topic has received little attention previously with the few studies made being limited in number of participants and different in approaches used and in questions asked. The present survey was sent to 279 former SI-PASS Leaders
Supplemental Instruction (SI) is a 47-year old proven peer-learning model that addresses student engagement, performance and retention as well as the transition to Higher Education (HE). SI was developed at the University of Missouri Kansas City in the US and has received wide recognition. Today the method has practitioners all over the United States as well as in several other countries around th
The present study focuses on the learning activities that are used in practice in supplemental instruction (SI) in basic engineering courses and the extent to which they are meaning oriented. A survey method, based on action verbs, is used and complemented with a student experience questionnaire on SI. The verbs chosen by both the students attending SI and the SI leaders to identify learning activ
This study focus on digital tools and software programmes used in SI. It combines a case study for the SI programme at Lund University with an international overview. The digital tools are divided in categories based on where they are used in SI. Digital tools for SI leaders are usually tools for communication with participants between sessions (Facebook, Messenger, WhatsApp, etc.); sharing good p
Enkelt uttryckt är Samverkansinlärning (SI) en studiecirkel kopplat till en utmanande kurs. SI leds av en senior student som utformar läraktiviteter där studenterna arbetar i grupper med att förklara och förtydliga svårt kursmaterial. Målsättningen med SI, förutom förbättrade prestationer i den aktuella kursen, är att studenterna skall utveckla goda studiestrategier och bli mer självständiga i sit
When you think of fungi, you’ll probably picture a huddle of chubby brown mushrooms, or the large, red-capped toadstools you stumble across in the woods. In doing so, you’re reducing fungi to their reproductive organs – tasty or striking as they may often be.
