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Peritoneal dialysis is a widely used, cost-effective and accessible renal replacement therapy. Theprimary aim of this thesis is to study and measure the mechanisms that govern fluid and electrolytetransport in peritoneal dialysis by combining theoretical models with experiments on rats and analysisof clinical datasets. Despite the apparent simplicity of the treatment, the physiological mechanisms
Eco-social policies aim to establish a social floor while respecting planetary boundaries and to improve the social outcomes of ecological policies. Research on public attitudes towards eco-social policies remains limited, focusing exclusively on people in high-income countries in Europe. Using representative samples in three diverse middle-income countries (Brazil, South Africa, China) and three
This chapter is an exploration of the concept of periphery when applied to regions. Specifically, it unpacks what we mean when we talk about places, specifically regions, as “peripheral”. It does this from the perspective of a sub-discipline of human geography: regional economic geography. In this field, peripheral regions are becoming increasingly interesting to researchers due to their key roles
Regional studies often treat the region as a sub‑national unit, and it spans from neighbourhoods to cross‑border macro‑regions. In Asia, this elasticity is intensified by language. Words that look equivalent on paper rarely carry identical histories, politics, or scales. This short piece reflects on the Chinese notion of quyu (区域) and how it travels between domestic and international contexts, see
We study time-dependent mediators in survival analysis using a treatment separation approach due to Didelez [Lifetime Data Analysis 25, no. 4: 593–610] and based on earlier work by Robins and Richardson [Causality and Psychopathology: Finding the Determinants of Disorders and Their Cures, 103–158. Oxford University Press]. This approach avoids nested counterfactuals and cross-world assumptions whi
A recent retrospective analysis of Enroll HD data suggesting β-blockers slow Huntington's disease progression has triggered patient demand but requires caution. The findings rely solely on small observational subsets and are vulnerable to bias and confounding. A prior Mendelian-randomization study found no causal link between β-blockers and HD onset; instead, genetically higher blood pressure was
Recent research shows that birth order affects human capital outcomes, yet there is limited empirical evidence on the underlying mechanisms. This study examines the effect of birth order on children's time use across activities that are important for human capital development. Using detailed time-use diaries of Australian children aged 2–15, we find that within families with two or three children,
Background: Posterior fossa tumours (PFT) are the most common childhood brain tumours, and children treated for these tumours are at increased risk of persistent speech, language and/or communication difficulties. Such difficulties have often been described in association with the postoperative complication cerebellar mutism syndrome (CMS), but can also occur in children without a period of mutism
Artikeln analyserar hur svenska myndigheter anpassade sin samhällsinformation till den kommersiella tv-reklamens logik i början av 1990-talet. Med Försäkringskassans omdebatterade kampanj med Ronny och Ragge inför Socialförsäkringens dag 1993 som fallstudie undersöks hur gränserna mellan kunskap, information och underhållning förhandlades i ett avreglerat medielandskap. Studien visar hur en tidiga
Context Substantial diagnostic delay in acromegaly contributes to increased morbidity and mortality. Screening attempts in high-risk groups have yielded few positive cases, underscoring the need for simple and precise prescreening methods. Objective Machine-learning analysis of facial images shows promise for acromegaly detection but requires validation in larger, well-characterized cohorts using
Detta kapitel ger en introduktion till digitala metoder inom idéhistoria, med särskilt fokus på hur studenter kan arbeta med text som data. Vi presenterar centrala begrepp som fjärrläsning, skalbar läsning och temamodellering, samt praktiska verktyg som Transkribus, RegEx och Voyant. Genom konkreta exempel visar vi hur digital textanalys kan identifiera mönster i stora textkorpusar och fungera som
Biodiversity offsetting (BO) is aimed to counterbalance biodiversity impacts from development projects. In Sweden, interest in BO within urban planning has grown since the mid-to-late 1990s, when the approach was first piloted in the municipality of Lomma. Because urban planning often involves non-protected nature, BO is not legally mandated but instead implemented on a voluntary basis. So far, ev
Microplastic (MP) pollution is increasingly recognized as a critical issue in coastal environments, where complex interactions between ocean currents, winds, waves, and human activities govern the transport and deposition of synthetic particles. Although previous studies in Asia have documented MPs accumulation linked to riverine discharge, tourism pressures, and monsoonal circulation, limited wor
The field of high energy physics (HEPs) has seen a marked increase in the use of machine learning (ML) techniques in recent years. The proliferation of applications has revolutionised many aspects of the data processing pipeline at collider experiments including the Large Hadron Collider (LHC). In this whitepaper, we discuss the increasingly crucial role that ML plays in real-time analysis (RTA) a
introduction to a reader with texts by Hannah Arendt, selected by Gertrud Sandqvist
Background Previous studies of minimally invasive liver surgery described results and experiences in high-volume centres and early adopters, but data on national levels are lacking. This study evaluated the implementation and outcomes of minimally invasive liver surgery in Sweden over a 15-year period, with a focus on colorectal liver metastases. Methods Data from patients undergoing liver surgery
Selective TDP-43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin-immunopositive cells compared to uninjected mice. AAV-mediated TDP-43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.
