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The impact of different passive protective measures against external vertical fire spread was investigated using the numerical tool Fire Dynamics Simulator (FDS). The numerical study was divided into a validation study and a comparative analysis. The validation study was performed to evaluate FDS as a calculation tool for modelling external vertical fire spread and was conducted using experimental
The present article argues that the fact that personal data holds great value, in combination with a lack of transparency in its commercial use, leads to a need for consumer policy that strengthens consumer protection. The widespread practice of user agreements and consent-based regulation of personal data collection is not satisfactory for balancing these information-asymmetric markets. The lack The present article argues that the fact that personal data holds great value, in combination with a lack of transparency in its commercial use, leads to a need for consumer policy that strengthens consumer protection. The widespread practice of user agreements and consent-based regulation of personal data collection is not satisfactory for balancing these information-asymmetric markets. The lack
The Gram-negative bacterial outer membrane contains lipopolysaccharide, which potently stimulates the mammalian innate immune response. This involves a relay of specialized complexes culminating in transfer of lipopolysaccharide from CD14 to Toll-like receptor 4 (TLR4) and its co-receptor MD-2 on the cell surface, leading to activation of downstream inflammatory responses. In this study we develop
The maximum work rate of animals has recently been suggested to be determined by the rate at which excess metabolic heat generated during work can be dissipated (heat dissipation limitation (HDL) theory). As a first step towards testing this theory in wild animals, we experimentally manipulated brood size in breeding marsh tits (Poecile palustris) to change their work rate. Parents feeding nestlinThe maximum work rate of animals has recently been suggested to be determined by the rate at which excess metabolic heat generated during work can be dissipated (heat dissipation limitation (HDL) theory). As a first step towards testing this theory in wild animals, we experimentally manipulated brood size in breeding marsh tits (Poecile palustris) to change their work rate. Parents feeding nestlin
Background: HPV vaccination programs have been introduced in large parts of the world, but monitoring of effectiveness is not routinely performed. Many countries introduced vaccination programs without establishing the baseline of HPV prevalences. We developed and validated methods to estimate protective effectiveness (PE) of vaccination from the post-vaccination data alone using references, which
Purpose: The aim of this study was to verify if radiotherapy (RT) safely can be omitted in older women treated for estrogen-receptor positive early breast cancer with breast-conserving surgery (BCS) and endocrine therapy (ET). Patients and Methods: Eligibility criteria were: consecutive patients with age ≥65 years, BCS + sentinel node biopsy, clear margins, unifocal T1N0M0 breast cancer tumor, Els
Background: Women with childbirth fear have been offered counseling by experienced midwives in Sweden for decades without evidence for its effectiveness, in terms of decrease in childbirth fear. Women are usually satisfied with the counselling. However, there is a lack of qualitative data regarding women's views about counselling for childbirth fear. Aim: To explore women's experiences of midwife-
Novel Sm2O3−NiO composite was prepared as the functional electrolyte for the first time. The total electrical conductivity of Sm2O3−NiO is 0.38 S cm−1 in H2/air condition at 550 °C. High performance, e.g. 718 mW cm−2, was achieved using Sm2O3−NiO composite as an electrolyte of solid oxide fuel cells operated at 550 °C. The electrical properties and electrochemical performance are strongly depended
The aim was to describe milk feeding patterns and first weaning foods during the first year of life in a large prospective birth cohort of infants with increased genetic risk for Type 1 diabetes (T1D) recruited in 4 different countries: the United States, Finland, Germany, and Sweden. All enrolled children with dietary information (n = 8,673) were included in the analyses; 1,307 (15%) children who
Hiatella is one of the most widespread marine bivalve genera, occurring in diverse habitats from the temperate to polar latitudes in both hemispheres, and in fossil strata since almost 150 Myr ago. Despite variation in some biological and morphological traits, characters to resolve the current systematic structure consistently across the range of the genus are not known: all samples are often refe
We present evidence of mitochondrial and nuclear introgression from the Atlantic herring Clupea harengus into the Pacific herring C. pallasii in northern European seas, where the two species have come into secondary contact following the post-glacial trans-Arctic invasion of Pacific herring to the Atlantic realm. Although the breeding areas of the two species are thought to be separate, 7 % of the
BackgroundThe relationships between North Atlantic and North Pacific faunas through times have been controlled by the variation of hydrographic circumstances in the intervening Arctic Ocean and Bering Strait. We address the history of trans-Arctic connections in a clade of amphi-boreal pelagic fishes using genealogical information from mitochondrial DNA sequence data. The Pacific and Atlantic herr
The Japanese skeleton shrimp Caprella mutica, originally from the north-west Pacific, artificially introduced to many parts of the world, is recorded in Sweden for the first time. The new record is from Eastern Skagerrak, slightly north of the border between the North Sea and the Baltic Sea. A detailed morphological description of the specimens from Swedish waters with notes on habitat is presente
Objective: Population-based osteoarthritis (OA) cohorts provide vital data on risk factors and outcomes of OA, however the methods to define OA vary between cohorts. We aimed to provide recommendations for combining knee and hip OA data in extant and future population cohort studies, in order to facilitate informative individual participant level analyses. Method: International OA experts met to m
We investigate the population of high-redshift (3≤z < 6) active galactic nuclei (AGN) selected in the two deepest X-ray surveys, the 7 Ms Chandra Deep Field-South and 2 Ms Chandra Deep Field-North. Their outstanding sensitivity and spectral characterization of faint sources allow us to focus on the sub-L* regime (logLX ≲ 44), poorly sampled by previous works using shallower data, and the obscured
This paper summarizes and elaborates on some new results on the optimal absorption in small spherical suspensions based on electrophoretic (plasmonic) resonances and lossy surrounding media. The main application here is to study the physical limitations for radio frequency absorption in gold nanoparticle (GNP) suspensions and its potential to achieve GNP targeted hyperthermia in cancer therapy. Nu
Background: The cerebral aqueduct is a central conduit for cerebrospinal fluid (CSF), and non-invasive quantification of CSF flow in the aqueduct may be an important tool for diagnosis and follow-up of treatment. Magnetic resonance (MR) methods at clinical field strengths are limited by low spatial resolution. Purpose: To investigate the feasibility of high-resolution through-plane MR flow measure
Introduction: In healthy carriers of the T allele of the transcription factor 7-like 2 (TCF7L2), fasting plasma glucagon concentrations are lower compared with those with the C allele. We hypothesised that presence of the T allele is associated with a diminished glucagon response during hypoglycaemia and a higher frequency of severe hypoglycaemia (SH) in type 1 diabetes (T1DM). Material and method
INTRODUCTION: The EUROpean Bone Over 40 Sarcoma Study (EURO-B.O.S.S.) was the first prospective international study for patients 41-65 years old with high-grade bone sarcoma treated with an intensive chemotherapy regimen derived from protocols for younger patients with high-grade skeletal osteosarcoma.METHODS: Chemotherapy based on doxorubicin, cisplatin, ifosfamide, and methotrexate was suggested
