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Anhedonia is a core and disabling symptom of mood disorders with limited treatment options. We evaluated the efficacy and safety of the dopamine agonist pramipexole in patients with mood disorders characterized by clinically significant anhedonia. In this single-center, randomized, double-blind, placebo-controlled trial, adults with major depressive disorder, dysthymia or bipolar depression and el

Online retail is growing rapidly, but fierce and global competition poses a challenge for retailers seeking to compete on values beyond price. Research in product and physical retail branding shows that building a relevant brand image can increase consumers’ willingness to pay a premium over competing brands with similar products. However, the academic literature lacks understanding of how brandin

Understanding how affect interacts with the neural dynamics of syntactic processing remains an open question in neurolinguistics. While syntactic anomaly detection has been extensively characterised through electrophysiological markers such as LAN and P600, the extent to which pervasive affective states, or moods, modulate these components is still poorly understood. Existing studies suggest that

Moisture‐induced deterioration is critical to building envelope durability in cold and temperate climates. To propose a new framework for selecting moisture design periods (MDPs) in Swedish building assemblies that capture sever moisture conditions more accurately, this paper evaluates different methods for producing MDPs. Using a 30‐year historical weather dataset as a benchmark, we compared simu

Purpose:Rapid changes in diet, physical activity and food systems have contributed to rising obesity in developing countries. As national incomes increase, obesity often shifts from higher to lower socioeconomic groups, a process known as the obesity transition. Small Island Developing States (SIDSs) face particular risks because of limited health system capacity, geographic isolation and dependen

The present study examined the cognitive mechanisms underlying decision-making in number-line estimation in 26 preschoolers through the lens of the evidence-accumulation paradigm. Children completed a traditional Number Line Estimation Task (NLET) and the Numeracy Screener test, which assessed symbolic and nonsymbolic abilities. They also completed a novel two-alternative forced-choice version of

Seagrass meadows have been proposed as a nature-based coastal protection measure to reduce incoming wave energy. Although numerous studies have demonstrated the capability of seagrass meadows to attenuate waves, their real-world effectiveness in providing coastal protection remains uncertain. The aim of this study was to quantify the influence of a Zostera marina meadow located in a non-tidal fetc

OBJECTIVE: Chronic inflammation of the urinary bladder is associated with the bladder pain syndrome. The treatment alternatives in humans are far from satisfactory and need further attention. Well-established preclinical models have shown that pro-inflammatory cytokines contribute to the progress of the inflammatory response behind pain and hyperalgesia. Previously presented results indicate that

The issue of riba, or interest, is crucial for both Islamic and non-Islamic countries. Western economic systems use the interest rate to efficiently distribute financial resources for investment and/or consumption. In the entire economic system outside the Islamic countries, interest rates are practically a prerequisite, for the functioning of the economic system. Islamic economies, on the contrar

I rapporten undersöks hur kommuner och regioner kan stärka sin ledningsförmåga – det vill säga förmågan att samordna beslutskraft och handlingskraft – i en tid präglad av komplexa samhällsutmaningar, begränsade resurser och höga krav på legitimitet och effektivitet. Rapporten baseras på intervjuer med ledande politiker och tjänstepersoner i åtta kommuner och tre regioner. Rapportens utgångspunkt äThis report examines how municipal and regional authorities can strengthen their capacity for leadership—that is, their ability to coordinate decisiveness with effective action—in a context characterised by complex societal challenges, constrained resources, and high demands for legitimacy and efficiency. The report is based on interviews with senior elected representatives and public officials in

The conversion of a blood meal into viable offspring is a central physiological challenge for female mosquitoes. A new study has found that rectal pad cells function as a peripheral neuroendocrine hub, sensing feeding-related signals and regulating reproductive investment, linking the hindgut to reproductive decision-making.

Diel rhythms synchronized to Earth's photic cycle are near-ubiquitous among animals living in regions with distinct day-night cues. Where such cues are reduced or absent, however, activity patterns may weaken, reorganize or become decoupled from the light-dark cycle, which may allow for more flexible behavioural expression. Using a dataset of >900 free-ranging black-legged kittiwakes from colonies

Description: In this episode, Linnéa Nordlander sits down with Natalia Kobylarz, who is a senior lawyer at the Registry of the European Courts of Human Rights. They discuss the Court's recent climate change jurisprudence, including Verein KlimaSeniorinnen and others v Switzerland, and how this builds on the Court's environmental case law.

In this episode, Beatriz Martínez Romera speaks with Simon Lex and Meng Zhang about the development and the regulatory and governance challenges surrounding green hydrogen in Denmark and the EU (RIGHydro and DART projects).

In this episode, Professor Trevor Daya-Winterbottom, Director of the Centre for Environmental, Resources and Energy Law at the University of Waikato, explores New Zealand’s actions in climate and environmental law.