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OBJECTIVES: Infectious agents like parvovirus have been implicated as exogenous factors that could trigger onset of systemic lupus erythematosus (SLE). A number of case reports describing a SLE-like presentation of acute human parvovirus B19 infection have been published, but no systematic investigation of the actual seroprevalence in epidemiologically defined SLE populations has previously been r
This is a biography of Allvar Gullstrand (1862-1930) on the occasion of the centennial of his 1911 Nobel Prize in physiology or medicine. We reviewed pertinent literature and we did archival studies at the Uppsala University Library and the Regional State Archives at Lund as well as the Nobel Archives at the Royal Swedish Academy of Sciences in Stockholm. Allvar Gullstrand was a brilliant scientis
The measurement of ensemble variability in time-aligned event signals is studied in relation to sampling rate requirements. The theoretical analysis is based on statistical modelling of time misalignment in which the time resolution is limited by the length of the sampling interval. For different signal-to-noise ratios (SNRs), the sampling rate is derived which limits the misalignment effect to le
The aim of this thesis is to study early life risk exposures in relation to adult health and mortality in Sweden during 250 years. A number of causal mechanisms by which exposure to diseases and stressful economic and social conditions early in life may lead to increased morbidity and mortality later in life are discussed (paper I). The early life exposures investigated are the foetal origins (nut
A rational, analytical approach to a fire engineering design of load-bearing steel structures is described. The method of design is directly based on the natural compartment fire concept and on strictly defined functional requirements and performance criteria. The method is permitted to be generally applied in Sweden, as one alternative, since about ten years. For facilitating the practical applic
Popular Abstract in Swedish Spårbarhet av livsmedel för att garantera ursprung, kvalitet och säkerhet i samband med produktion och transport har blivit alltmer uppmärksammat i samhället. Kraven på att livsmedel skall vara kvalitetsmässigt säkerställda samt miljömässigt hållbara har vuxit sig starkare från konsumenter såväl som från myndigheter. En bidragande orsak är den ökade fokuseringen kring bFood traceability is gaining increased attention in food companies and governmental authorities. This is because of the increase in legal and consumer requirements on ensuring food safety, quality and preservation of living resources. These requirements especially apply to the management of food traceability in regulated fresh food supply chains. Several studies have shown that management of food
The MBA case method of how to use cases steam from Harvard and has almost become a norm for what the case method represents concerning the purpose, form and content. However, the Lund University School of Economics and Management (LUSEM) way of using cases differs from the MBA Case Method in several important aspects. This paper discusses the potential merits of using an alternative approach (LUSE
The Major Intrinsic Proteins, MIPs, constitute a large, ancient superfamily of membrane proteins that are found in all kingdoms of life. Most MIPs facilitate passive diffusion of water across biological membranes (aquaporins), although many channels are also permeable for glycerol and other small uncharged solutes, (aquaglyceroporins). Other substrates reported for specific MIPs are anions, carbon
The complexity of systems for automatic control and other safety-critical applications grows rapidly. Computer software represents an increasing part of the complexity. As larger systems are developed, we need to find scalable techniques to manage the complexity in order to guarantee high product quality. Memory management is a key quality factor for these systems. Automatic memory management, or
Popular Abstract in Swedish Polymerer och tensider är två mycket vanliga molekylslag som vi ofta stöter på i vårt vardagliga liv. Polymerer är extremt långa kedjor sammansatta av tusentals repeterande enheter. De förekommer både som hårda material (t ex plast) och i lösning (t ex målarfärg). Det finns syntetiska polymerer, såsom nylon och polyeten, och det finns biologiska polymerer, t ex cellulosA new approach to the study of aqueous mixtures of oppositely charged polymers and surfactants has been introduced. Pure polyion-surfactant ion complex salts have been synthesized and used as the point of departure. The elimination of the simple ions reduces the number of components in the mixtures, thus greatly simplifying the system. By mixing the complex salt with either the polyelectrolyte or
IMPORTANCE Bipolar disorder is associated with premature mortality, but the specific causes and underlying pathways are unclear. OBJECTIVE To examine the physical health effects of bipolar disorder using outpatient and inpatient data for a national population. DESIGN, SETTING, AND PARTICIPANTS National cohort study of 6 587 036 Swedish adults, including 6618 with bipolar disorder. MAIN OUTCOMES AN
We propose and analyze the use of hybrid microwave cavities as quantum heat engines. A possible realization consists of two macroscopically separated quantum-dot conductors coupled capacitively to the fundamental mode of a microwave cavity. We demonstrate that an electrical current can be induced in one conductor through cavity-mediated processes by heating up the other conductor. The heat engine
Presently there is an abundance of sites, across media, promoting acts of communal reading (televised book clubs, web rings, publishers’ book discussion questions, etc.). This article forms a case study of what usages of reading and concurrently what reading subjects are framed in the Swedish televised book club, Malous bokklubb (Malou’s Book Club), modelled on Oprah’s Book Club in the USA and Ric
BACKGROUND The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of
There are accelerating trends for the implementation of electronic commerce(e-commerce) as an extra marketing channel for selling products globally via the access of the Internet. This is expected to in¯uence the shape of future cities and the conservation of natural resources. This paper critically reviews the current research work to date regarding the environmental implications of e-commerce. T
Fibromuscular dysplasia (FMD) mainly affects renal arteries. Percutaneous transluminal renal angioplasty (PTRA) and surgery are effective treatments, but longtime follow-up is lacking. Retrospective follow-up for 7.0 +/- 4.7 years of 69 consecutive patients ( age 44 +/- 13 years) treated for hypertension due to FMD, 59 patients underwent PTRA and eight patients surgery. In two patients no PTRA was
Neoglycoconjugates were prepared from mannan isolated from yeast Saccharomyces cerevisiae and activated by periodate oxidation to create aldehyde groups. Various degrees of oxidation introduced 11-28 aldehyde groups per mannan molecule and simultaneously resulted in a molar mass decrease from 46 to 44.5-31 kDa. The activated mannans were subsequently conjugated with bovine serum albumin forming ne
Background: We were concerned that a fixed rather than a weight-based dosing regimen of dalteparin sodium to prevent venous thromboembolism. (VTE) might result in decreased efficacy in obese patients and decreased safety in elderly patients. Methods: We retrospectively performed subgroup analyses using the database from the Prospective Evaluation of Dalteparin Efficacy for Prevention of VTE in Imm
