Filetype
Aims: To evaluate outcome in the first generation of children with end-stage heart disease to whom heart transplantation was available. Methods: Retrospective review of all 135 Swedish children <18 years old listed for heart transplantation 1989-2009, followed to December 31, 2009, including 74 (55%) with cardiomyopathy and 61 (45%) with congenital heart disease; 34 (25%) were infants (<1 year).
The purpose of this study was to compare the non-invasive 3D pseudo-continuous arterial spin labelling (PC ASL) technique with the clinically established dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-MRI) for evaluation of brain tumours. A prospective study of 28 patients with contrast-enhancing brain tumours was performed at 3 T using DSC-MRI and PC ASL with whole-brai
Background: Respiratory tract deposition of air pollution particles is a key to their adverse health effects. This study was aimed to determine the size-resolved deposition fraction (DF) of sooty wood smoke particles in the lungs of healthy subjects. The type of wood smoke investigated is typical for household air pollution from solid fuels, which is among the largest environmental health problems
AIM: To investigate plasma levels of the neutrophil-borne heparin-binding protein (HBP) in patients with induced hypothermia after cardiac arrest (CA), and to study any association to severity of organ failure, incidence of infection and neurological outcome. METHODS: This study included 84 patients with CA of mixed origin who were treated with hypothermia. Plasma samples from 7 time points during
Sheet-metal forming involves a complex strain distribution over the part. The strains consist of tension, compression, and a mix of both. A geometry has been developed, the X-Die, in order to gain insight into the strain behavior of different materials. The X-Die enables strain paths far into the tension/compression region, thus creating the possibility to extend the experimental base both for def
Aromatic amino acids play an important role in ultraviolet (UV)-induced photochemical reactions in proteins. In this work, we aim at gaining insight into the photochemical reactions induced by near-UV light excitation of aromatic residues that lead to breakage of disulfide bridges in our model enzyme, Fusarium solani pisi cutinase, a lipolytic enzyme. With this purpose, we acquired transient absor
Background Estimation of skin diseases in the community is challenging because we do not easily have access to the nonhealthcare-seeking population. A potential tool is a questionnaire asking for self-reported skin complaints. Such an instrument has not yet been developed. Objectives To validate a simple instrument assessing skin morbidity in the general adult population, to predict clinical skin
PURPOSE: We measured serum levels of human glandular kallikrein 2 (hK2) in patients with prostate cancer treated with radical retropubic prostatectomy for clinically localized prostate cancer to determine whether preoperative hK2 levels discriminate stage pT2a/b from pathological stage T3a or greater cancer. This finding would help to predict preoperatively the organ confined versus non-organ conf
We used stochastic dynamic programming to investigate a spectacular migration strategy in the black brant Branta bernicla nigricans, a species of goose. Black brant migration is well suited for theoretical analysis since there are a number of existing strategies that easily can be compared. In early autumn, almost the entire population of the black brant gathers at Izembek Lagoon on the Alaska Pen
Popular Abstract in Swedish Elektrolyter är ämnen som sönderdelas i ett lösningsmedel och därvid ger upphov till positivt och negativt laddade joner. De starka elektrostatiska krafter i lösningen som detta i sin tur orsakar är typiska för elektrolytlösningar. Redan vid små tillsatser av en elektrolyt till ett lösningsmedel kan lösningens egenskaper förändras kraftigt. Lösningar av elektrolyter speA thermodynamic model for electrolyte solutions has been derived for binary and multicomponent solutions up to very high molalities. The model was extensively tested on 163 binary aqueous electrolyte systems up to very high molalities, and the results show that the model represents mean ionic activity coefficients and osmotic coefficients very accurately. The model parameters vary significantly be
The thesis concerns experimental studies of bubble motion and the transport of large particles and bubbles. Bubbly flows are encountered in many engineering applications where the bubbles play an important role for the mass transfer between the phases, e.g. in stirred reactors. A special case of bubble transport is the cavitation phenomenon, which mainly has a negative effect on the performance of
In this chapter, the advantages and disadvantages of 3D fast spin echo (FSE) pCASL as a measure of brain tumor perfusion are reviewed. In addition, we compare pCASL with other perfusion techniques and discuss future ASL approaches. A prospective study of 28 patients with contrast-enhancing brain tumors was performed at 3 T using dynamic susceptibility contrast (DSC) MRI and pCASL. The visual quali
Introduction. Along with the great expansion of research being published in Open Access (OA) journals over the last decade, the interest for analysing the OA literature using informetric methods has also increased. Most studies have focused on the citation impact of OA journals and whether OA publishing increases the chances of a research publication being cited. Fewer analyses, however, have inve
Popular Abstract in Swedish Hjärtinfarkt och kärlkramp orsakas av förändringar i hjärtats kranskärl pga åderförkalkninng (ateroskleros). Fettinlagring i kärlväggen leder dels till förträngning och dels till bildning av ömtåliga plack som plötsligt kan spricka. Denna kärlväggsskada försöker kroppen reparera genom aktivering av blodets levringssystem (koagulation). Det är i denna situation inte heltThe triggering mechanism in myocardial infarction (MI) and unstable angina involves coronary thrombus formation following plaque rupture. Coagulation is initiated by tissue factor that activates factor VII (FVII), and is inhibited by protein C and its co-factor protein S. Resistance to activated protein C (APC resistance) is a common risk factor for venous thrombosis caused by a mutation in the ge
Who can pick a winner? Since 1974, various types of targeted support have at different times been directed at the development of the heat pump market in Sweden – which in the following decades oscillated violently between soaring sales and collapse. Eventually, however, small heat pumps for space heating of residential buildings have in recent years securely established themselves as a mature and
Manager och Civil Servant är en utforskning av aktörers förgivet tagna antaganden vilka styr uppfattningar kring hur offentlig förvaltning ska ske i samtida välfärdsstater. Det hävdas att mer än 30 år av pågående och riktade reformer gentemot den offentliga förvaltningen har orsakat dilemman att uppstå. Dessa dilemman har resulterat i en förskjutning av balansen kring några fundamentala pelare inoManager and Civil Servant is an exploration of actors’ taken-for-granted assumptions that govern perceptions concerning how public administration should be undertaken within contemporary welfare states. It is argued that more than 30 years of continuous reforms directed towards public administration have caused dilemmas to arise. These dilemmas have resulted in a shifting of balances regarding the
We have evaluated capacitive and thermal transducers for recognition of bio- molecular interactions with different analytes. These assays were made in flow analysis systems because of the simplicity such methods provide. A capacitive transducer, based on a surface modified gold electrode, has the ability to monitor affinity based interactions directly, provided that the interactions introduce mea
The Major Intrinsic Proteins, MIPs, constitute a large, ancient superfamily of membrane proteins that are found in all kingdoms of life. Most MIPs facilitate passive diffusion of water across biological membranes (aquaporins), although many channels are also permeable for glycerol and other small uncharged solutes, (aquaglyceroporins). Other substrates reported for specific MIPs are anions, carbon
