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We present a detailed chemical analysis of 22 stars along thecolour-magnitude sequence of the intermediate-age (1.7 Gyr) open clusterIC 4651, based on high-resolution, high S/N ratio spectra from UVES/VLT.IC 4651 thus becomes one of the few open clusters for which a detailedcomposition analysis exists for stars spanning 3.5 mag, from solar-typemain-sequence stars to giants above the RGB clump. In
Recent progress in the study of surfactant-responsive polymer gels is reviewed. Polymer gels can be designed that drastically swell or shrink in response to small changes in the concentration of an ionic surfactant in an external bath containing the gel. The gel swelling isotherm, where the equilibrium gel volume is measured as a function of the external surfactant concentration, yields useful inf
In this 24-month follow-up of a phase II study in patients with castration-resistant prostate cancer (CRPC) and bone metastases, radium-223 (4 injections of 50 kBq/kg every 4 weeks [n = 33]) improved median overall survival vs. matching placebo (n = 31) (65.3 vs. 46.4 weeks, respectively; log-rank P = .056), with no long-term safety concerns. Data suggest that treatment of bone disease with radium
Food production and consumption have a range of sustainability implications, including their contribution to global emissions of greenhouse gases (GHGs). As some foodstuffs entail higher GHG emissions than others, managing their use in tourism-related contexts could make a significant contribution to climate change mitigation. This article reviews the carbon intensity of selected foods and discuss
Lately, much work in the area of voltage stability assessment has been focused on finding post-contingency corrective controls. In this article a contribution to this area will be presented where we search for maximal loadability while considering post-contingency corrective controls. This objective is different from the usual approach to the problem, where the aim is to include the post-contingen
IMPORTANCE The introduction of biological tumor necrosis factor inhibitors has improved the treatment of rheumatoid arthritis (RA) but at a substantial cost. These drugs have been shown to lead to superior radiological outcomes compared with a combination of conventional disease-modifying antirheumatic drugs over 2 years. OBJECTIVE To investigate whether radiological superiority translates into be
Bai Nuur (41 degrees 38.590'N, 114 degrees 30.922'E, similar to 1346 m a.s.l.) and Ulan Nuur (41 degrees 44.214'N, 115 degrees 05.630'E, similar to 1246 m a.s.l.) are two small lakes situated in the transition zone between semi-humid and semi-arid climate regimes that runs parallel to the present limit of the southeast monsoon along the southeastern Inner Mongolia Plateau in north China. A 215 cm-
The pedagogic purposes and ambitions of both museums and archives are in many ways alike. Their intentions and purposes as institutions in our society are also in many ways very similar to each other, not at least when it comes to the fact that they are both working towards preserving and communicating our cultural heritage and our history. Still though the museums are much better known, recognize
The doctrine of utmost good faith in insurance contracts has long been a part of English law. It was codified with the Marine Insurance Act 1906. In the pre-formation stage the doctrine consists of a duty to avoid non-disclosure and misrepresentation. Which facts are to be disclosed or represented under the doctrine is determined by a test of materiality. The assured does not have a duty to disclo
This paper examines in which ways civil society can contribute to the consolidation of democracy in post-transition societies. The theoretical groundwork draws on Caroline Boussard's framework for analysis from her book Crafting Democracy, which distinguishes four functions of civil society for post-transition democratization (agenda setter, educator, counterpart, source of new political alter
Animals have evolved multiple sensory systems that can acquire environmental information guiding their behaviour, allowing them to adapt physiological parameters to current conditions. However, over the past century, anthropogenic changes have increasingly made information on environmental conditions less reliable, by introducing novel elements (such as synthetic chemicals or artificial light), by
Municipalities shoulder the burden of creating business-friendly environments – managing infrastructure, navigating public resistance, and investing countless hours in smoothing the path for economic development. Yet, the rewards often flow elsewhere. Local taxes on economic activity offer a powerful solution. While a thriving local economy boosts budgets, different taxes shape municipal decision-
Pimavanserin was the first US Food and Drug Administration approved antipsychotic drug that does not block D2 dopamine receptors at therapeutic doses. Pimavanserin is a selective 5-HT2A receptor inverse agonist that reduces the frequency of hallucinations and delusions associated with Parkinson disease. Despite these attributes, pimavanserin prolongs the QT interval at therapeutic doses, limiting
Arbetet är utfört åt skogsforskningsstationen Mógilsá som ligger strax norr om Reykjavik. Forskningen inom Mógilsá bedrivs inom delar av eller för hela Island med inriktning inom exempelvis dendrokronologi, proveniensförsök, och studier av insekter. Sedan 1900-talets början har inplantering av exotiska trädarter blivit allt vanligare och i en allt större skala. Syften med inplanteringen är bland aThis study was made in an attempt to give the forest research centre Mógilsá a produced tetratherm map and a better understanding of how topography and temperature influence the growth of two tree species. The digital tetratherm map model, covering the northern part of Iceland, was developed to investigate the correlation between tetratherm and the growth of Picea sitchensis and Larix (sukaczewii
Evaluations provide insights into the effectiveness of emergency exercises or the response to a disaster. A well-constructed process is key to capture evidence-based feedback that can support future learning and development. However, little is known about how they are performed in practice and whether they actually meet their intended purpose. Therefore, this paper provides an overview of how ‘ope
This presentation gives an overview of a peer learning model and academic support intervention named SI-PASS (Supplemental Instruction – Peer Assisted Study Schemes) in Higher Education in Europe. SI-PASS is a method of improving student performance in “difficult”, normally introductory, courses combining “how to learn” with “what to learn”. SI-PASS sessions are scheduled parallel to the regular e
The problem of antibiotic resistance is rising continuously, creating a warning signal that calls for finding alternatives. Not only that, but there is also a rising demand for natural food preservatives. The pharmaceutical and food industry sectors are working on fulfilling these needs. This thesis is exploring possible solutions to these issues. The research studies presented here introduce the
Mounting evidence indicates that the presence of cardiovascular disease (CVD) and risk factors elevates the incidence of cognitive impairment (CI) and dementia. CVD and associated decline in cardiovascular function can impair cerebral blood flow (CBF) regulation, leading to the disruption of oxygen and nutrient supply in the brain where limited intracellular energy storage capacity critically depe
Defects in the synthesis pathways of amino acids have only been discovered in recent years and are relatively unknown to most clinicians. In this chapter disorders neurological symptoms caused by genetic defects in the synthesis of the amino acids serine, glutamine and proline are discussed. Patients with serine deficiency invariably suffer from severe neurological symptoms such as microcephaly, p
Background: The efficacy of cervical cancer screening programs is dependent on the participation rate. To increase participation among women not attending cervical cancer screening, self-collected samples for detection of high-risk human papillomavirus (hr-HPV) may be an option. The aims of this study were: to investigate the response rate to sending a self-collected vaginal sample for hr-HPV mRNA
