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The aim of this study was to evaluate the predictive value of intratumoural microvessel density in breast cancer. We studied immunohistochemically primary tumours of 104 patients with metastasised breast cancer who took part in a randomised multicentre trial comparing docetaxel to sequential methotrexate and 5-fluorouracil. Vessels were highlighted with factor VIII staining and counted microscopic
In this paper, we analyse the functioning of private capital markets in Holland in the late medieval period. We argue that in the absence of banks and state agencies involved in the supply of credit, entrepreneurs' access to credit was determined by two interrelated factors. The first was the quality of property rights protection and the extent to which properties could be used as collateral. The
OBJECTIVE: The aim of this study was to describe the clinical characteristics of early onset prostate cancer, with special reference to family history as a possible prognostic factor.MATERIAL AND METHODS: We identified all cases of prostate cancer diagnosed before the age of 51 in the Southern health care region in Sweden between 1958 and 1994. Clinical data were collected retrospectively from med
Background: Ventricular tachycardia (VT) occurs intermittently, unpredictably, and has potentially lethal consequences. Objective: Our aim was to derive a risk prediction model for VT episodes ≥10 beats detected on 30-day mobile cardiac telemetry based on the first 24 hours of the recording. Methods: We included patients who were monitored for 2 to 30 days in the United States using full-disclosur
Objective To explore timing in relation to all types of adverse events (AEs), severity and preventability for patients undergoing acute and elective hip arthroplasty. Design A multicentre cohort study using retrospective record review with Global Trigger Tool methodology in combination with data from several registers. Setting 24 hospitals in 4 major regions of Sweden. Participants Patients ≥18 ye
Questions in causality, control, and reinforcement learning go beyond the classical machine learning task of prediction under i.i.d. observations. Instead, these fields consider the problem of learning how to actively perturb a system to achieve a certain effect on a response variable. Arguably, they have complementary views on the problem: In control, one usually aims to first identify the system
Technological innovation is still a challenge for SMEs in emerging countries, mainly due to the lack of financial, structural, capital, and proper managerial resources. Covid-19 presented a scenario that increased difficulties for companies, especially of this kind, and at the same time presented a necessity-driven impulse to look for innovative solutions. This study aimed to analyze the drivers o
This paper investigates an integrated traffic environment modeling and model predictive control (MPC) system to realize interaction-aware dynamic motion planning of an autonomous vehicle with multiple surrounding vehicles. The interaction-aware interacting multiple model Kalman filter (IAIMM-KF) from the literature is used to hierarchically predict maneuvers and trajectories of surrounding vehicle
Promoting a more sustainable development of urban realities is one of the most important goals of the recent decades. One possible strategy to undertake in order to achieve this objective is the implementation of a road pricing: tolling private cars when passing by certain roads of the network could be a way to tone down the traffic congestion and, at the same time, encourage the shifting towards
This thesis contributes to empirical research in labor economics. It consists of three self-contained papers.The first paper, The Effect of Paid Vacation on Health: Evidence from Sweden, analyzes the causal effect of paid vacation on health. Using register data on the universe of central government employees in Sweden, I exploit an age-based rule stipulated in the collective agreement covering the
Background: Managing acute abdominal pain in the large and growing population of Roux-en-Y gastric bypass (RYGB)–operated patients poses a challenge to general surgeons, because of diagnostic limitations and the risk of internal herniation. Objective: To investigate the diagnoses, management, and outcome of RYGB patients admitted for acute abdominal pain. Setting: University Hospital, Sweden. Meth
The focus of this master’s thesis is to evaluate the effect of reactive programming on Playtech BGT Sports content server. The effect is evaluated mainly from a performance aspect, but a development process aspect is also taken into consideration. The content server is working in real-time and is required to have low latency and high throughput of processing of data. These characteristics are impo
Spx or why bacteria don’t suffer from burnout Bacteria also suffer from stress. In general, any fluctuation in the environment of bacteria can cause stress on them. For instance, too hot or too cold temperature, or changes in the pH. In order to survive, they need mechanisms to cope with it. Most of these mechanisms involve proteins, which can be seen as tools that respond to stress. In the bac
När byggnader och broar ska dimensioneras är det viktigt att knutpunkterna för konstruktionen är noggrant beräknade. För att utföra beräkningar som tar hänsyn till knäckning och andra fenomen används ofta datorberäkningar i viss utsträckning. Det tar ofta oerhört lång tid, både för användaren att skapa en modell för konstruktionen i den grad av detalj som behövs, samt för datorprogrammet att beräkWhen designing large complex steel structures numerical calculation methods are always used to some extent. The simulation technology of today is advanced and can with proper modeling technique provide detailed analyses which captures the structural response accurately. For most projects it is not reasonable to analyze a complete structure in exact detail and therefore simplified methods are used
In response to Loures Municipal Council’s recent proposal for redeveloping the Vila Valente Quarter of Moscavide, an area in urgent need of intervention, by demolishing, starting from scratch and relocating its vulnerable residents, this thesis challenges our responsibilities as architects when it comes to community development, especially with respect to the marginalised in society. We understand
Köparens undersökningsplikt vid företagsöverlåtelser skiljer sig väsentligt från andra typer av förvärv. Köplagen (KöpL) är, trots vissa brister, den mest rimliga lagen att tillämpa för att hantera frågor i samband med företagsförvärv. Felbegreppet är svårtolkat när det gäller överlåtna aktier i ett förvärvat bolag men det mest centrala för själva undersökningsplikten är; säljarens handlande, främThe buyer’s obligation to scrutinize a corporate acquisition differs significantly from other types of acquisitions. The Swedish Sales of Goods Act (KöpL) is, despite certain shortcomings, the most reasonable law to deal with issues regarding corporate acquisitions. The concept of error is difficult to interpret when it comes to shares in an acquired company but the most crucial aspect regarding t
The aim of this thesis is to investigate the main tasks and factors that affect the Swedish rescue service’s capability to handle an accident with hazardous materials. To accomplish this aim, two methods were used: a literature review and interviews. The literature review was carried out to identify tasks and factors, and also to understand the subject and the available research on the topic. Inte
Titel: Valutarisken inom Stockholmsbörsen, en kvantitativ undersökning av OMXS30- bolagens valutaexponering. Seminariedatum: 1 juni 2023. Ämne/kurs: FEKH89, Examensarbete i finansiering på kandidatnivå. Författare: Felix Hult, Mahdi Rahideh & André Rosdahl. Handledare: Göran Andersson. Nyckelord: Valutarisk, valutaexponering, OMXS30, aktieavkastning, hedging. Forskningsfråga: 1. Påverkas värdeTitle: The Foreign Exchange Risk of the Stockholm Stock Exchange, a Quantitative Analysis of the Foreign Exchange Risk Exposure of OMXS30-Firms. Seminar date: 1 June 2023. Course: FEKH89, Bachelor’s Thesis in Corporate Finance. Authors: Felix Hult, Mahdi Rahideh & André Rosdahl. Advisor: Göran Andersson. Key words: Foreign exchange risk, Foreign exchange exposure, OMXS30, stock return, hedging
Purpose: In this study, we examine the data from Chinese companies to test the relationship between cash flow and investment. While a wide assortment of previous research has examined the relationship between cash flow and investment, they have largely focused on empirical analysis from an US or a Western perspective. But, to date, little attention has been paid to such relationship using empirica
