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Bacterial interference-is deliberate colonization with Escherichia coli 83972 an alternative treatment for patients with recurrent urinary tract infection?

The increasing microbial antibiotic resistance motivates research for non-antibiotic treatment alternatives. In recurrent urinary tract infections (UTIs), 'bacterial interference' has attracted interest as a possible alternative treatment option. The observation that asymptomatic bacteriuria (ABU) protects against recurrent UTI has prompted clinical trials with deliberate colonization of the human

Early activation of Broca's area in grammar processing as revealed by the syntactic mismatch negativity and distributed source analysis

Though activation of Broca's region in the combinatorial processing of symbols (language, music) has been revealed by neurometabolic studies, most previous neurophysiological research found the earliest grammar indices in the temporal cortex, with inferior-frontal generators becoming active at relatively late stages. We use the attention- and task-free syntactic mismatch negativity (sMMN) event-re

XUV-induced transient phase gratings for probing ultra-fast carrier generation and recombination processes in wide-bandgap semiconductors

A method for probing the temporal evolution of ultra-fast carrier generation and recombination processes in wide-bandgap semiconductors, e.g. diamond, is described. Two extreme ultraviolet (pump) pulses produced by high-order harmonic generation in Argon gas (with a photon energy of 32 eV) are superimposed on a sample with a small angle between them, inducing periodic changes in the refractive ind

On Mechanisms Impairing Airway Host Defence in Cystic Fibrosis

Popular Abstract in Swedish Cystisk fibros (CF) är en ärftlig sjukdom som orsakas av en defekt jonkanal. Denna defekt ger upphov till en onormal saltbalans i kroppen och följderna blir många. I lungorna och magtarmkanalen produceras ett väldigt segt slem vilket täpper till luftvägarna och medför andningssvårigheter. De slemfyllda lungorna klarar inte av att transportera upp slemmet och istället stCystic fibrosis is an inherited disease, caused by mutations of the cystic fibrosis transmembrane conductance regulator gene. The gene codes for a protein that serve as chloride channel. In cystic fibrosis, this protein is lacking or has a defect function resulting in a thick and sticky mucus of the airways. The altered airway environment promotes mucus and growth of pathogenic bacteria. A common

A network of social security bodies – European administrative cooperation under Regulation (EC) No 883/2004

In the EU regime on the coordination of social security, there are rules and principles on cross-border administrative cooperation. Through these legal mechanisms, a number of cooperation structures are established with the Administrative Commission as a central point. Within these structures, national social security bodies provide assistance, communicate directly, solve conflicts of interpretati

A method for maintaining constant ethanol concentrations in cell culture media

The present study reports on the development of a model for maintaining constant ethanol concentrations over time in cell culture media. When neuroblastoma x glioma cells (NG 108-15) were grown in ethanol containing media under standard cultivation conditions in the incubator at 37 degrees C, a 90% evaporation was observed after 24 hr. To counteract evaporation, the cell culture dishes were placed

The effect of moisture gradients on tensile strength perpendicular to grain in glulam

Experimental results are presented concerning tension perpendicular to grain in glulam sections where internal stresses induced by climate changes are present. The results reveal that moisture induced internal stresses may affect the tension capacity both in a positive and a negative way compared to reference specimens, free from moisture gradients. The tension capacity is reduced during moistenin

Large-area microfocal spectroscopic ellipsometry mapping of thickness and electronic properties of epitaxial graphene on Si- and C-face of 3C-SiC(111)

Microfocal spectroscopic ellipsometry mapping of the electronic properties and thickness of epitaxial graphene grown by high-temperature sublimation on 3C-SiC (111) substrates is reported. Growth of one monolayer graphene is demonstrated on both Si- and C-polarity of the 3C-SiC substrates and it is shown that large area homogeneous single monolayer graphene can be achieved on the Si-face substrate

Long-term organic farming fosters below and aboveground biota: Implications for soil quality, biological control and productivity

Organic farming may contribute substantially to future agricultural production worldwide by improving soil quality and pest control, thereby reducing environmental impacts of conventional farming. We investigated in a comprehensive way soil chemical, as well as below and aboveground biological parameters of two organic and two conventional wheat farming systems that primarily differed in fertiliza

Analysis of genes coding for CD46, CD55 and C4b-binding protein in patients with idiopathic, recurrent, spontaneous pregnancy loss.

Since a tightly regulated complement system is needed for a successful pregnancy, we hypothesized that alterations in complement inhibitors may be associated with idiopathic, recurrent miscarriage. We sequenced all exons coding for three complement inhibitors: C4b-binding protein (C4BP), CD46 and CD55 in 384 childless women with at least two miscarriages that could not be explained by known risk f

Fast metabolite mapping in the pig heart after injection of hyperpolarized (13) C-pyruvate with low-flip angle balanced steady-state free precession imaging.

The conversion of hyperpolarized (13) C pyruvate to metabolic products in the Krebs cycle provides valuable information about the metabolic status and the viability of the myocardium. Therefore, imaging methods must be able to spectrally discriminate different (13) C metabolites. However, the requirement for spectral selectivity conflicts with the demands for rapid image acquisition and high spati

Frequency- and Phase-Sensitive Magnetomotive Ultrasound Imaging of Superparamagnetic Iron Oxide Nanoparticles

It has recently been demonstrated that superparamagnetic iron oxide nanoparticles can be used as magnetomotive ultrasound contrast agents. A time-varying external magnetic field acts to move the particles and, thus, the nanoparticle-laden tissue. However, the difficulty of distinguishing this magnetomotive motion from undesired movement induced in regions without nanoparticles or other motion arti

Management and prognostic features of intracerebral hemorrhage during anticoagulant therapy - A Swedisih multicenter study

Background and Purpose-Patients treated with oral anticoagulants (ACs) have an increased risk of intracerebral hemorrhage (ICH), which is more often fatal than spontaneous ICH. Options to reverse the AC effect include intravenous administration of vitamin K, plasma, and coagulation factor concentrate. However, the optimal management of AC-related ICH has not been determined in any randomized trial

A Wall of Cash - The Investment Cash Flow-Sensitivity when Capital Becomes Abundant

In the mid 2000s the oil and gas industry was hit by what might be best described as a ‘wall of cash’ as oil prices successively reached new record levels and access to external financing improved greatly. In this article we investigate what this sudden abundance of liquidity implied for the investment-cash flow relationship, the interpretation of which continues to generate controversy in the fin

Videoradiography of free jejunal grafts for rehabilitation of speech in laryngectomized patients

In laryngectomized patients a tracheo-esophageal artificial fistula can be used to achieve air flow from the trachea to the esophagus during speech. A one-way plastic valve is often used for the fistula. A free jejunal graft between the trachea and the esophagus can also be used. To avoid aspiration the transplant is attached to the submental area giving the graft a siphon-like shape. We performed

Towards returns management strategies in internet retailing

The digital transformation of the retailing industry in recent years has had a profound effect on consumers’ behaviour on a global scale. When shopping and browsing online, consumers are not able to “touch and feel”, which means that product returns are inevitable. The fashion industry has particularly suffered from high return rates, which fluctuate between 30% and 50%. The industry has been stru

Changes in health-related quality of life among older adults aging with long-term spinal cord injury

Study design: Cross-sectional and longitudinal. Objectives: To (i) describe health-related quality of life (HRQoL) and changes over 6 years in older adults aging with long-term spinal cord injury (SCI) and (ii) investigate how changes in HRQoL are associated with age, gender, and injury characteristics. Setting: Community in southern Sweden. Methods: From the initial 123 participants (years 2011–2

Reduction of rod and cone function in 6.5-year-old children born extremely preterm

OBJECTIVE To compare retinal function via full-field electroretinographic (ffERG) recordings in 6.5-year-old children born extremely preterm with children born at term. DESIGN, SETTING, AND PARTICIPANTS A subcohort studywas conducted from July 1, 2010, to January 15, 2014, of the national Extremely Preterm Infants in Sweden Study, including preterm children (<27 weeks' gestational age) and childre

Are found defects an indicator of software correctness? An investigation in a controlled case study

In quality assurance programs, we want indicators of software quality, especially software correctness. The number of found defects during inspection and testing are often used as the basis for indicators of software correctness. However, there is a paradox in this approach, since the remaining defects is what impacts negatively on software correctness, not the found ones. In order to investigate