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In this review, we summarise the current understanding of the potential link between cancer and anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), including granulomatosis with polyangiitis (Wegener's; GPA) and microscopic polyangiitis (MPA). As is true for many autoimmune or inflammatory rheumatic diseases, AAV diagnosis and therapy are associated with an increased risk of de novo
Vehicles in the future are anticipated to have the ability to communicate and exchange useful information in order to avoid collisions. However, for this cooperation to be possible all vehicles will have to be equipped with compatible wireless IEEE 802.11p modules that implement intelligent transport systems operating in the 5 GHz frequency band standard (ITS-G5 or WAVE). During the implementation
The microflora of Herrgård cheese produced at three dairies was compared after three and six months maturation. The microflora of cheeses from two of the dairies was dominated by a spontaneous microflora of Lactobacillus after three months of ripening, while starter bacteria still dominated in cheese from the third dairy after six months. Isolates were typed by the PCR-based method Randomly
Popular Abstract in Swedish Pulserande stjärnrester (OBS! Kontakta mig för figurerna eller se artikeln publicerat i Populär Astronomi). Rubina Kotak, Populär Astronomi, 2002, Nr 2, sid. 29 Stjärnorna's utveckling: Solen är idag ungefär fem miljarder, alltså fem tusen miljoner år gammal. Hur ser solen's framtiden ut? Som i de allra flesta stjärnor, pågår även i solen's innersta delar kärn reaktiSeveral analyses using time-resolved optical spectrocopy of pulsating white dwarfs are presented. The data have been put to a number of uses. First, line-of-sight velocities associated with the pulsations have been measured in three hydrogen-atmosphere white dwarfs (DAVs), bringing the total number of such measurements up to five. They have also been measured for the first time in a pulsating heli
One of the keys to the development of novel anti-infective strategies. Over the last fifteen years it has become increasingly obvious that bacteria are not as simple and solitary as once believed. Rather, an accumulating body of work shows that bacteria are highly complicated and social organisms, constantly sensing their surroundings and altering both their environments and behaviors to ensure su
Introduction of roughness by ribs in flow passages is a popular method of enhancing heat transfer in the cooling passages, e.g., of turbine blades and combustors. It is essential to accurately predict the enhancement of heat transfer generated by the ribs to ensure good design decisions. In most of the studies square ribs have been considered, but in practice such ribs may appear rounded due to im
The paper reports a project conducted within the framework of the National Library of Sweden's Expert Group on Library Statistics. The project is financed by the National Library of Sweden, and it aims to capture how library managements make use of the current library statistics (based on the ISO-standard) in the decision-making process. Questions are also asked about the quality and usefulness of
Introduction. Manual delineation of the left ventricle is clinical standard for quantification of cardiovascular magnetic resonance images despite being time consuming and observer dependent. Previous automatic methods generally do not account for one major contributor to stroke volume, the long-axis motion. Therefore, the aim of this study was to develop and validate an automatic algorithm for ti
Background. Several studies have investigated associations between the -174GC single nucleotide polymorphism (rs1800795) of the IL6 gene and phenotypes related to type 2 diabetes mellitus (T2DM) but presented inconsistent results. Aims. This joint analysis aimed to clarify whether IL6 -174GC was associated with glucose and circulating interleukin-6 concentrations as well as body mass index (BMI).
Background The methyl ester form of fumaric acid named dimethyl fumarate (DMF) is an effective mould-growth inhibitor. Its irritating and sensitizing properties were demonstrated in animal models. Recently, DMF has been identified as responsible for furniture contact dermatitis in Europe. Objective To describe the clinical manifestations, patch test results, shoe chemical analysis, and source of e
Major efforts to develop antibody microarray technology to enable global proteome analysis to be performed in a facile manner are under way. In this process, the design and the properties of the substrate will play crucial roles. In the present study, we have developed novel, highly biocompatible solid supports for microarrays, using adsorbed recombinant human single-framework antibody fragments a
Population-based metaheuristic algorithms are powerful tools in the design of neutron scattering instruments and the use of these types of algorithms for this purpose is becoming more and more commonplace. Today there exists a wide range of algorithms to choose from when designing an instrument and it is not always initially clear which may provide the best performance. Furthermore, due to the nat
Following the 2004-5 Orange Revolution, President Viktor Yushchenko embarked on an ambitious project to rehabilitate the Organization of Ukrainian Nationalists (OUN) and its armed wing, the Ukrainian Insurgent Army (UPA). Following the Euromaidan Revolution and Russia’s invasion of Ukraine in 2014, a more systematic effort was made to affirm these groups as a center of a new historical canonical c
More than three decades ago, Thomas Alerstam initiated the study of orientation and navigation of migratory songbirds in southern Sweden. Stensoffa Ecological Field Station, located approx. 20 km east of Lund, has since been a primary location for orientation experiments. However, it has often been difficult to record well-oriented behaviour in the seasonal appropriate migratory directions, in par
Flame emission spectra and OH* imaging are carried out together with planar laser-induced fluorescence (PLIF) of OH and CH2O to characterize the reaction zone structures of three combustion modes, i.e. a flame mode, a transition mode and a flameless mode, established in a laboratory combustor. Spectroscopic measurements indicate that the invisibility of the flameless mode can be attributed to a mo
OBJECTIVE: To describe the lived experience of being a homebirth midwife in the Nordic countries.METHODS: Interviews conducted with 21 homebirth midwives from the five Nordic countries were analyzed with a phenomenological approach.RESULTS: The essential structure of being a homebirth midwife in the Nordic countries can be understood as realizing altruistic values and fulfilling one's own desires
A continuous integrated bioprocess available from the earliest stages of process development allows for an easier, more efficient and faster development and characterization of an integrated process as well as production of small-scale drug candidates. The process presented in this article is a proof-of-concept of a continuous end-to-end monoclonal antibody production platform at a very small scal
We present a software package, Modes, offering h-adaptive and p-adaptive linear multistep methods for first order initial value problems in ordinary differential equations. The implementation is based on a new parametric, grid-independent representation of multistep methods [Arévalo and Söderlind 2017]. Parameters are supplied for over 60 methods. For nonstiff problems, all maximal order methods (
Uric acid is the end product of dietary and endogenous purine metabolism in humans and higher primates. In all lower mammalian species it is converted to allantoin by liver uricase. The aim of this study was to investigate the uric acid turnover in pig model after nephrectomy surgery, fructose-enriched diet and potassium oxonate application. The first experiment was performed using 4 intact contro
