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Predicting Changes in Cardiovascular Risk Factors in Type 2 Diabetes in the Post-UKPDS Era: Longitudinal Analysis of the Swedish National Diabetes Register.

The aim of the current study was to provide updated time-path equations for risk factors of type-2-diabetes-related cardiovascular complications for application in risk calculators and health economic models. Observational data from the Swedish National Diabetes Register were analysed using Generalized Method of Moments estimation for dynamic panel models (N = 5,043, aged 25-70 years at diagnosis

A systematic review on physical therapy interventions for patients with binge eating disorder

Purpose: Since a distorted body experience and a sedentary lifestyle are central in the course of binge eating disorder (BED), physical therapy might be an interesting add-on treatment. The aim of this study was to systematically review randomised controlled trials (RCTs) evaluating physical therapy on binge eating and physical and mental health in BED patients. Method: EMBASE, PsycINFO, PubMed, C

Differences in estimates of cisplatin-induced cell kill in vitro between colorimetric and cell count/colony assays

The aim of this study was to evaluate some bioassays that are different in principle: cell counting, colony forming assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT), sulforhodamine B (SRB), crystal violet, and alamarBlue, with respect to their ability to measure cisplatin-induced cell death of in vitro-cultivated squamous cell carcinoma of the head and neck (SCCHN). Cispl

W=0 pairing in Hubbard and related models of low-dimensional superconductors

Lattice Hamiltonians with on-site interaction W have W = 0 solutions, that is, many-body singlet eigenstates without double occupation. In particular, W = 0 pairs give a clue to understand the pairing force in repulsive Hubbard models. These eigenstates are found in systems with high enough symmetry, like the square, hexagonal or triangular lattices. By a general theorem, we propose a systematic w

High prevalence of Hepatozoon spp. (Apicomplexa, hepatozoidae) infection in water pythons (Liasis fuscus) from tropical Australia

Molecular methods were used to identify blood parasites frequently observed in blood smears of water pythons (Liasis fuscus) captured in our study area in the Northern Territory of Australia. A nested polymerase chain reaction (PCR) using primers amplifying the 18s ribosomal RNA (IRNA) nuclear gene resulted in a short PCR product (180 bp) matching this region in the genus Hepatozoon. However, beca

Effects of soil pH and phosphorus on in vitro pollen competitive ability and sporophytic traits in clones of Viola tricolor

Greenhouse-grown clones of Viola tricolor were used to evaluate the importance of genetic effects on in vit ro pollen tube growth rate in relation to the influence of two environmental soil factors-pH and phosphorus content. After 1 mo in different soil treatments, individual pollen tube growth rate was affected by a genotype by phosphorus interaction, while it was unaffected by either main effect

Universal temperature and body-mass scaling of feeding rates

Knowledge of feeding rates is the basis to understand interaction strength and subsequently the stability of ecosystems and biodiversity. Feeding rates, as all biological rates, depend on consumer and resource body masses and environmental temperature. Despite five decades of research on functional responses as quantitative models of feeding rates, a unifying framework of how they scale with body

OSL chronology for a sediment core from the southern Baltic Sea: A continuous sedimentation record since deglaciation

A chronology based on optically stimulated luminescence (OSL) dating is presented for the late- and post-glacial evolution of the southern Baltic Sea (-15ka to present). During this period, large water level and salinity changes occurred in the Baltic Basin due to opening and closing of connections to the North Atlantic. Previous attempts to establish a chronology for these palaeoenvironmental cha

A generic detailed rigid-body lumbar spine model

The objective of this work is to present a musculo-skeletal model of the lumbar spine, which can be shared and lends itself to investigation in many locations by different researchers. This has the potential for greater reproducibility and subsequent improvement of its quality from the combined effort of different research groups. The model is defined in a text-based, declarative, object-oriented

Male mating constraints affect mutual mate choice: prudent male courting and sperm-limited females.

Costs of sperm production may lead to prudence in male sperm allocation and also to male mate choice. Here, we develop a life history-based mutual mate choice model that takes into account the lost-opportunity costs for males from time out in sperm recovery and lets mate competition be determined by the prevailing mate choice strategies. We assume that high mating rate may potentially lead to sper

Of sheep and rain: large-scale population dynamics of the red kangaroo

1. We analysed time-series data from populations of red kangaroos (Macropus rufus, Desmarest) inhabiting four areas in the pastoral zone of South Australia. We formulated a set of a priori models to disentangle the relative effects of the covariates: rainfall, harvesting, intraspecific competition, and domestic herbivores, on kangaroo population-growth rate. 2. The statistical framework allowed fo

Stochastic Modelling and Reconstruction of Random Shapes

This thesis originates from the problem of reconstructing the three-dimensional shape of objects, when the only available data are two-dimensional images. The solution presented is based on stochastic models for random object shapes and measurements, in combination with practical surface representation and simulation methods. As a means to handle general, unknown object types, stochastic models f

Spanish research on avian migration: historical trajectory and future perspectives.

Aim: To value the importance of research on avian migration for the development and current status of Spanish ornithology. Results and Conclusions: Avian migration has always been an outstanding field in ornithology. This assertion is particularly true in Spain, as we illustrate here by discussing the contribution of migration research to both the scientific and historical development of Spanish o

A reassessment of the neuropathology of frontotemporal dementia linked to chromosome 3

A large Danish family has previously been reported in which autosomal dominant frontotemporal dementia (FTD) is genetically linked to chromosome 3 (FTD-3). A mutation was recently identified in the CHMP2B gene that is probably responsible for causing disease in this family. Because of its neuropathologic findings, FTD-3 was originally categorized as a subtype of frontotemporal lobar degeneration,

Nonlinear compartmental model of F-18-choline

Introduction: This work develops a compartmental model of F-18-choline in order to evaluate its biokinetics and so to describe the temporal variation of the radiopharmaceuticals' uptake in and clearance from organs and tissues. Methods: Ten patients were considered in this study. A commercially available tool for compartmental analysis (SAAM II) was used to model the values of activity concentrati

Assessment of oxidative burst in avian whole blood samples: Validation and application of a chemiluminescence method based on Pholasin

Immunoecology deals with the questions about how immune defences have evolved and are being used and optimized in different environments, ecological settings and lineages. In such research, often only single time point measures and small sample volumes are available, which limits the applicability of traditional immunological methods. Methodological progress in the field thus largely depends on th

Validation and analysis of detailed kinetic models for ethylene combustion

Present work aims at evaluation of contemporary comprehensive detailed kinetic mechanisms for ethylene combustion, including the Konnov mechanism, LLNL nButane mechanism, San Diego (UCSD) mechanism and USC mechanism. These models have been validated by extensive comparison with available experimental data on ethylene ignition and flame propagation. The experimental data from the literature have be

Vehicle Detection through Wireless Vehicular Communication

Vehicles in the future are anticipated to have the ability to communicate and exchange useful information in order to avoid collisions. However, for this cooperation to be possible, all vehicles will have to be equipped with compatible wireless modules, based on, e.g. IEEE 802.11p (used in ITS-G5 or WAVE), which implements intelligent transport systems operating in the 5 GHz frequency band. During

Characterization of different FAD-dependent glucose dehydrogenases for possible use in glucose-based biosensors and biofuel cells.

In this study, different flavin adenine dinucleotide (FAD)-dependent glucose dehydrogenases (FADGDHs) were characterized electrochemically after "wiring" them with an osmium redox polymer [Os(4,4'-dimethyl-2,2'-bipyridine)(2)(PVI)(10)Cl](+) on graphite electrodes. One tested FADGDH was that recently discovered in Glomerella cingulata (GcGDH), another was the recombinant form expressed in Pichia pa