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Fast method to find sterically possible amino acid substitutions

With the growing pool of deposited protein structures, the need for structural analysis tools grows. In study of amino acid substitutions the variety of analysis tools is high; nevertheless, there is a lack of programs serving specific purpose, such as identifying if an amino acid substitution would cause a clash in the structure or not, given just the structure of the original protein. In this stAnalysing structural damage caused by changes in proteins In an organism, even only one single change of an amino acid can sometimes lead to disease, if the protein is a part of an important biological function. Because of that, it is important to study those changes and be able to predict if an amino acid substitution would cause harm. There are various ways a substitution can be harmful to a pr

UBE2D3 is a positive prognostic factor and is negatively correlated with hTERT expression in esophageal cancer

Human telomerase reverse transcriptase (hTERT) is a critical factor in unlimited cell proliferation and immortalization, with numerous studies demonstrating that high expression of hTERT is a poor prognostic factor in various types of cancer. Ubiquitin-conjugating enzyme E2D 3 (UBE2D3) is a member of the E2 family, and participates in the ubiquitin proteasome pathway to regulate basic cellular act

Management of used packaging in the European Union

Packaging is one of the logistics areas where there often is potential and even a demand for improvements. An increase in environmental awareness among the population in the European Union (EU) has generated a demand for changes in packaging, which has led to stricter rules and regulations. Knowledge about what regulations are present and what may be expected in the future is crucial in the formin

Second-hand Smoke, Cotinine Levels, and Risk of Circulatory Mortality in a Large Cohort Study of Never-Smokers.

BACKGROUND:: Exposure to second-hand smoke has been shown to be associated with increased cardiovascular mortality in several, but not all, epidemiologic studies. Our aim was to investigate the risk of circulatory death associated with exposure to second-hand smoke in never-smokers in a very large prospective study, the European Prospective Investigation into Cancer and Nutrition. A secondary aim

Osteoporosis knowledge and awareness among university students in Saudi Arabia

Awareness and knowledge about any disease is the first step to prevent and treat it, so this study evaluates osteoporosis awareness and knowledge in university students. Our results showed a high awareness and good knowledge of osteoporosis. Females were better informed than males. Knowledge increased with increasing education level. PURPOSE: Osteoporosis is a worldwide health problem, including S

Cytogenetic studies of normal kidney tissue and renal cell carcinoma

Popular Abstract in Swedish Njurcancer är ungefär den 10:e vanligaste tumörformen i Sverige och diagnosticeras nästan dubbelt så ofta hos män som hos kvinnor. Tumörerna upptäcks vanligtvis i åldern mellan 50 och 70 år och de mest förekommande symtomen är blod i urinen och flanksmärtor. Varför man får njurcancer är inte känt, men det finns ett klart samband med rökning och asbest. Njurcancer kan upIn the present thesis normal kidney tissue and renal cell carcinoma (RCC) were studied by cytogenetic and fluorescence in situ hybridization (FISH) methods to investigate chromosomal aberrations. In the first study, 4 samples of nonneoplastic kidney tissue were cultured for cytogenetic analysis and trisomy 7 was found in all cases in 3-15% of the cells. In the second study, cytogenetic analysis o

Epilepsy in tuberous sclerosis complex : Findings from the TOSCA Study

Objective: To present the baseline data of the international TuberOus SClerosis registry to increase disease Awareness (TOSCA) with emphasis on the characteristics of epilepsies associated with tuberous sclerosis complex (TSC).Methods: Retrospective and prospective patients' data on all aspects of TSC were collected from multiple countries worldwide. Epilepsy variables included seizure type, age a

Outcome of the Swedish Nationwide abdominal aortic aneurysm screening program

Background: A general abdominal aortic aneurysm (AAA) screening program, targeting 65-year-old men, has gradually been introduced in Sweden since 2006 and reached nationwide coverage in 2015. The aim of this study was to determine the outcome of this program. Methods: Data on the number of invited and examined men, screening-detected AAAs, AAAs operated on, and surgical outcome were retrieved from

Cause-Specific Mortality in Gout : Novel Findings of Elevated Risk of Non–Cardiovascular-Related Deaths

Objective: To examine cause-specific mortality beyond cardiovascular diseases (CVDs) in patients with gout compared to the general population. Methods: We included all residents of Skåne (Sweden) age ≥18 years in the year 2002. Using the Skåne Healthcare Register, we identified subjects with a new diagnosis of gout (2003–2013) and matched each person with gout with 10 comparators free of gout, by

Treatment with oestrogen or manual separation for labial adhesions - initial outcome and long-term follow-up

Background: Topical oestrogen and manual separation are the main treatments for labial adhesions. The aim was to evaluate treatment of labial adhesions and compare the outcome of topical oestrogen treatment with that of manual separation. Method: All girls aged 0-12 years admitted to a tertiary centre for paediatric surgery for labial adhesions were included. The study design was dual: The first p

Evaluation of absorbed dose and image quality in mammography

Popular Abstract in Swedish Utvärdering av stråldos och bildkvalitet i mammografi Bröstcancer är den cancerform som är vanligast hos kvinnor. Genom tidig upptäckt med bröströntgen, mammografi, kan man behandla sjukdomen i ett tidigare stadium och därmed minska dödligheten. Det är också möjligt att behandla på ett skonsammare sätt vid tidig upptäckt. Därför har man startat hälsokontroller, screeniMammography refers to the X-ray examination of the human breast, and is considered the single most important diagnostic tool in the early detection of breast cancer, which is by far the most common cancer among women. There is good evidence from clinical trials, that mammographic screening can reduce the breast cancer mortality with about 30%. The side effects include a small and age related risk

A step "not" beyond ethnicity in Rwanda: Political mythology and social identity: Report from a Swedish International Development Cooperation Agency Minor Field Study, October - December 1999

The aim of this work is to study present Rwandan social identities. The aim is made operational by posing the question; how are group identities produced and reproduced in Rwanda? In order to answer this the study uses the bourdieuesian notion of habitus, incorporated products of history that are active principles for unification of practices and representations, as the analytical concept of socia

Renal and Cardiovascular Complications Following Type 2 Diabetes Mellitus in People With and Without HIV : Data from Cohort Study on Morbidity and HIV in Sweden (COSMOHS) between 2010-2024

BACKGROUND: Type 2 diabetes mellitus (T2DM) is common among people with HIV (PWH), although studies comparing T2DM-related complications in people with and without HIV (PWoH) remain limited. This was assessed using data from the Cohort Study on Morbidity and HIV in Sweden (COSMOHS).METHOD: Nationwide study including Swedish residents born 1930-2006, diagnosed with T2DM between 2010 and 2019, follo

Lunds-universitets-magasin-4-2014

Hopp för unga med Parkinsons Nya ingångar till utbildning Ledarskap på gott och ont Tidsresan Lunds universitets magasin | nr 4 | 2014 sLäkten besökte anfaders verk 2 LUM nr 4 | 2014 LUM nr 4 | 2014 3 Här styrs undervisningen av bönetiderna 3 t övre raden: Vardagsbilder i Abu Dahbi. Irén Tiberg utanför Sheikh Zayed Grand Mos- que i Abu Dhabi. nedre raden: Systrarna Nabras och Salamah Al Qahtani, t

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-4-2014.pdf - 2026-05-27

Naturvetare skriver popularvetenskap

1 Inledning Naturvetare skriver populärvetenskap Susanne Pelger1 Sara Santesson2 Gunlög Josefsson2 1Naturvetenskapliga fakulteten 2Nordiska språk, Språk- och litteraturcentrum Lunds universitet 2010 2 Abstract One of the generic learning outcomes to be achieved by science students at Lund University is the ability to communicate science also to a non- specialist audience. In this report we analyze

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/naturvetare_skriver_popularvetenskap.pdf - 2026-05-27

170303 vr start up poster final hq

1. Rapid Urbanisation and Climate Change In cities in the developing world, rapid urbanisation and climate change are combining to dramatically increase exposure to flood risk among the poorest and most vulnerable (Jha et al, 2012). This is because informal settlements consistently form in high flood-risk areas alongside rivers and other natural drainage paths (Parikh et al, 2012) and because inad

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/170303_vr_start_up_poster_final_hq.pdf - 2026-05-27

Kris- Och Beredskapsplan För Campus Helsingborg Rev 250605

Postadress: Box 882, 251 08 Helsingborg Besöksadress: Universitetsplatsen 2, Helsingborg Telefon: 0709-565793, 046-222 00 00 E-post: jerker.jacobsson@ch.lu.se Webbadress: www.ch.lu.se Utveck l ingsenheten Campus Hels ingborg Jerker Jacobsson , admin is t ra t iv chef Kris- och beredskapsplan för Campus Helsingborg Datum 2025-06-05 1 1 Diarienummer STYR V2025/1588 Kris- och beredskapsplan 2 Innehål

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-06/Kris-%20och%20beredskapsplan%20f%C3%B6r%20Campus%20Helsingborg%20rev%20250605.pdf - 2026-05-27

Kris- Och Beredskapsplan För Campus Helsingborg Rev 250825

Postadress: Box 882, 251 08 Helsingborg Besöksadress: Universitetsplatsen 2, Helsingborg Telefon: 0709-565793, 046-222 00 00 E-post: jerker.jacobsson@ch.lu.se Webbadress: www.ch.lu.se Utveck l ingsenheten Campus Hels ingborg Jerker Jacobsson , admin is t ra t iv chef Kris- och beredskapsplan för Campus Helsingborg Datum 2025-08-25 1 1 Diarienummer STYR V2025/1588 Kris- och beredskapsplan 2 Innehål

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-08/Kris-%20och%20beredskapsplan%20f%C3%B6r%20Campus%20Helsingborg%20rev%20250825.pdf - 2026-05-27

Lunds-universitets-magasin-9-2012

Mer makt åt akademiska ledare! Bränslecell driver framtidens bil Klimatmätning på hög nivå Arabisk höst Lunds universitets magasin | nr 9 | 2012 demokrater driLLas i oPinionsBiLdning 2 LUM nr 9 | 2012 LUM nr 9 | 2012 3 – Ska vi ta något om artificiell fotosyntes – att kunna efterlikna naturen vore ju fantastiskt, men det kanske är för bra för att vara sant? Eller satsa på nanotrådar som kan minska

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-9-2012.pdf - 2026-05-27