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Popular Abstract in Swedish De perifera nervstammarna i extremiteterna förmedlar signaler, dels till muskler, dels från känselkroppar som är belägna i bl a huden. Nervstammarna kan av olika orsaker utsättas för skador orsakade av vassa eller skärande föremål eller av olika typer av slitvåld. Nervskador ger ett mycket stort handikapp för den enskilde patienten som förlorar muskelfunktion och känselNerve injuries have a profound impact on individuals, suffering for the patients and induce cost for society. When dealing with severe nerve injuries that create a gap between nerve segments or when the injury is at the brachial plexus level, the clinical alternatives are limited. The brachial plexus model and its branches in the forelimb was evaluated as an experimental model for studies of nerve

Today our economy is largely based on linear material flows, and many products, such as electronics, furniture,building materials and textiles, are discarded even when they could still be used. Without urgent action, globalwaste is expected to increase by 70% by 2060 and global materials use is expected to more than double. We arestarting to realise that linear material flows are not only a loss o

Three speakers engaged with theatre in different ways (professor, director, actor, lecturer, philosopher) got inspired by the dialogical structure of Brecht’s Buying Brass and staged a similarly structured conversation. This conversation imitated the way how thespians and intellectual met in Brecht’s original text, but it was thematically focused on the current socio-cultural context. The research

Context. The velocity distribution of stars in the solar neighbourhood is inhomogeneous and rich with stellar streams and kinematic structures. These may retain important clues regarding the formation and dynamical history of the Milky Way. However, the nature and origin of many of the streams and structures is unclear, hindering our understanding of how the Milky Way formed and evolved. Aims. We

In this paper, we study activity on Twitter in relation to the Swedish political festival Almedalsveckan, a week-long event where political parties, interest organizations, corporations and other actors for decades have gathered on the island of Gotland to discuss politics and public affairs. In 2018, a total of 4311 events (speeches, seminars, debates etc.) were arranged by 1929 separate actors a

Background: Over the past couple of decades, measuring immunological parameters has become widespread in studies of ecology and evolution. A combination of different immunological indices is useful for quantifying different parts of the immune system and comprehensively assessing immune function. Running multiple immune assays usually requires samples to be repeatedly thawed and re-frozen. There i

One of the major features of prostate cancer (PCa) is its heterogeneity, which often leads to uncertainty in cancer diagnostics and unnecessary biopsies as well as overtreatment of the disease. Novel non-invasive tests using multiple biomarkers that can identify clinically high-risk cancer patients for immediate treatment and monitor patients with low-risk cancer for active surveillance are urgent

The burden of cardiometabolic diseases is increasing worldwide. Early detection of high-risk individuals is essential for appropriate diagnosis, better treatment outcomes, quality of life and lower health related costs. Aims: The overall aim of this thesis is to investigate the possible associations between plasma proneurotensin (Pro-NT) and risk of cardiovascular disease (CVD), type 2 diabetes (T

Objective: To investigate the effects of fever therapy compared with no fever therapy in a wide population of febrile adults. Design: Systematic review with meta-analyses and trial sequential analyses of randomised clinical trials. Data sources: CENTRAL, BIOSIS, CINAHL, MEDLINE, Embase, LILACS, Scopus, and Web of Science Core Collection, searched from their inception to 2 July 2021. Eligibility cr

Metallic glasses are non-crystalline metals that are obtained by rapid cooling of the melt to bypass crystallization. The amorphous atomic structure shows enhanced properties relative to the crystalline counterpart. For example, enhanced mechanical properties, improved corrosion resistance, as well as excellent soft magnetic properties. The unique properties of metallic glasses make them promising

Introduction: Fetal growth restriction is a major risk factor for adverse perinatal outcome. As most of the growth-restricted fetuses are small for gestational age (SGA), an efficient antenatal screening method for SGA fetuses would have a major impact on perinatal health. The aim of this study was to compare the SGA prediction rate achieved with third-trimester routine ultrasound estimation of fe

In a world where copyright is being infringed in a plethora of ways, consumers find it difficult to access legal digital content. Therefore, this thesis investigates how copyright law governs access to legal content in the digital environment in respect of so-called consumptive use.  By apprehending a user-centric approach I evaluate whether and how copyright law accounts for the consumer interest

Background: Patients with bladder pain syndrome experience debilitating pain and extreme frequency of urination. Numerous therapeutic approaches have been tested, but as the molecular basis of disease has remained unclear, specific therapies are not available. Objective: Recently, a systematic gene deletion strategy identified interleukin-1 (IL-1) hyperactivation as a cause of severe cystitis in a

BACKGROUND: Individuals with multiple islet autoantibodies are at increased risk for clinical type 1 diabetes and may proceed gradually from stage to stage complicating the recruitment to secondary prevention studies. We evaluated multiple islet autoantibody positive subjects before randomisation for a clinical trial 1 month apart for beta-cell function, glucose metabolism and continuous glucose m

Background: The persistent environmental contaminants perfluoroalkyl substances (PFASs) have gained attention due to their potential adverse health effects, in particular following early life exposure. Information on human fetal exposure to PFASs is currently limited to one report on first trimester samples. There is no data available on PFAS concentrations in fetal organs throughout all three tri

AbstractAnkylosing spondylitis (AS) and undifferentiated spondyloarthritis (USpA) are two subgroups of the rheumatic disease spondyloarthritis (SpA). The diseases typically debut in early adulthood with periods of fluctuating and persistent pain and stiffness, and can result in consequences such as impaired functioning and reduced quality of life. SpA is a heterogenous group but AS and USpA share

Background: Patients with non-small cell lung cancer (NSCLC) harboring a ROS proto-oncogene 1 (ROS1)-rearrangement respond to treatment with ROS1 inhibitors. To distinguish these rare cases, screening with immunohistochemistry (IHC) for ROS1 protein expression has been suggested. However, the reliability of such an assay and the comparability of the antibody clones has been debated. Therefore we e

Background: Early blight, caused by the necrotrophic fungal pathogen Alternaria solani, is an economically important disease affecting the tuber yield worldwide. The disease is mainly controlled by chemical plant protection agents. However, over-using these chemicals can lead to the evolution of resistant A. solani strains and is environmentally hazardous. Identifying genetic disease resistance fa

Most recent programming languages, such as Java, Python and Ruby, include a collection framework as part of their standard library (or runtime). The Java Collection Framework provides a number of collection classes, some of which implement the same abstract data type, making them interchangeable. Developers can therefore choose between several functionally equivalent options. Since collections hav

The diverse, largely Neotropical subtribe Euptychiina is widely regarded as one of the most taxonomically challenging groups among all butterflies. Over the last two decades, morphological and molecular studies have revealed widespread paraphyly and polyphyly among genera, and a comprehensive, robust phylogenetic hypothesis is needed to build a firm generic classification to support ongoing taxono