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PURPOSE: In recent years, there has been an increasing interest in flattening-filter free (FFF) beams. However, since the removal of the flattening filter will affect both the mean and the variance of the energy spectrum, current beam-quality specifiers may not be adequate for reference dosimetry in such beams. The purpose of this work was to investigate an alternative, more general beam-quality s
Various applications need an electric machine that can provide a wide range of torque over a broad range of rotation speed and temperature. Dynamic testing, where the machine acceleration is compared to the deceleration slope, allows to scan through a wide scope of operation points with insignificant temperature rise. Therefore, the goal of this paper is to analyse the consistency of the rapid exp
This chapter introduces basic differences between Free/Open Source Enterprise Resources Planning systems (FOS-ERP) and Proprietary ERP (P-ERP), revisiting the previous work of Carvalho (2008). Taking into account that some years has passed and the economic downturn came, it updates key aspects of FOS-ERP under both vendor and adopter perspectives. Like its predecessor, this chapter contributes to
Vision plays a paramount role in some spider families such as the Salticidae, Lycosidae and Thomisidae, as it is involved in prey hunting, orientation or choice of substrate. In the thomisid Misumena vatia, for which the substrate colour affects the body colour, vision seems to mediate morphological colour changes. However, nothing is known about which component of visual signals from the substrat
Dampness in indoor environments may cause various health problems. The specific causative agent(s) are unknown but may originate from degradation processes in damp materials, microbial growth, or a combination of these phenomena. The health impact of dampness in buildings is a politically, legally, and economically important question. Scientists at the U.S. EPA and Lawrence Berkeley National Labor
Recent work has confirmed that genetic compatibility among mates can be an important determinant of siring success in sperm competition experiments and in free-ranging populations. Most of this work points towards mate choice of less related mates. However, there may also be the potential for mate choice for intermediate or even genetically similar mates to prevent outbreeding depression or hybrid
Most viruses in human skin are known to be human papillomaviruses (HPVs). Previous sequencing of skin samples has identified 273 different cutaneous HPV types, including 47 previously unknown types. In the present study, we wished to extend prior studies using deeper sequencing. This deeper sequencing without prior PCR of a pool of 142 whole genome amplified skin lesions identified 23 known HPV ty
Background Clinical classification of rare sequence changes identified in the breast cancer susceptibility genes BRCA1 and BRCA2 is essential for appropriate genetic counselling of individuals carrying these variants. We previously showed that variant BRCA1 c.5096G>A p.Arg1699Gln in the BRCA1 transcriptional transactivation domain demonstrated equivocal results from a series of functional assays,
Popular Abstract in Swedish Vid 1990-talets början drabbades Sverige av en omfattande lågkonjunktur. De unga som då skulle etableras på arbetsmarknaden var födda kring 1970-talets mitt. De fick erfara arbetslöshet och socialbidragstagande i avsevärt högre omfattning än någon tidigare generation i den moderna svenska välfärdsstaten. Trots ett förbättrat arbetsmarknadsläge fanns en grupp unga vuxna In the early 1990s a severe economic recession struck Sweden. The generation about to establish themselves on the labour market at this time were born in the mid seventies. They experienced unemployment and welfare dependency to a considerably higher extent than any previous generation in the modern Swedish welfare state. Despite the recovery of the Swedish economy a group of young adults, now in
This paper is intended to give a short overview of the epidemiologic and experimental data on cancer risks associated with very low radiation absorbed doses. The paper will also discuss methods to present these data in an understandable way to those who are exposed e. g. in medical diagnostics and after a radiological or nuclear accident.
Like many engineering programs in Europe, the final part of most Swedish software engineering programs is a longer project in which the students write a Master's thesis. These projects are often conducted in cooperation between a university and industry, and the students often have two supervisors, one at the university and one in industry. In particular, the Bologna Process that is currently unde
Objective: Advanced glycation end products (AGE) have been implicated in diabetic vascular complications through activation of pro-inflammatory genes. AGE-modified proteins are also targeted by the immune system resulting in the generation of AGE-specific autoantibodies, but the association of these immune responses with diabetic vasculopathy remains to be fully elucidated. The aim of this study w
Background and Purpose-Genetic variation influences risk of intracerebral hemorrhage (ICH). Hypertension (HTN) is a potent risk factor for ICH and several common genetic variants (single nucleotide polymorphisms [SNPs]) associated with blood pressure levels have been identified. We sought to determine whether the cumulative burden of blood pressure-related SNPs is associated with risk of ICH and p
Popular Abstract in Swedish Bakterier är små encelliga organismer som lever i nästan varje tänkbar miljö på jorden, inklusive i och på människor. Vi är kontinuerligt koloniserade av bakterier i bland annat våra luftvägar, munhålor och mag-tarmkanaler. Denna samexistens är oftast ömsesidigt fördelaktig, eller åtminstone ofarlig för oss människor, och det är känt att bakterier hjälper oss bryta ner Nontypeable Haemophilus influenzae (NTHi) is a remarkably proficient colonizer of the human respiratory tract. The aim of this thesis has been to characterize currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to host tissue and evasion of the host innate immunity. We have shown that the NTHi virulence factor Pr
Abstract A reliable and simple-to-use algorithm was developed for the energy-calibration of double-sided silicon strip detectors (DSSSDs). It works by enforcing mutual consistency of p-side and n-side information for every detected event. The procedure does not rely on a dedicated data set for calibration and is robust enough to work fully automated without human supervision. The method was develo
