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Malaria is a major global cause of deaths and a vaccine is urgently needed.

This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. Microparticles might be shed from

Motor complications of Parkinson's disease (PD) are a consequence of pulsatile dopaminergic stimulation from standard oral levodopa therapy. Levodopa-carbidopa intestinal gel (LCIG) is infused continuously via an intrajejunal percutaneous gastrostomy tube. This was the first study designed to characterize the full pharmacokinetic profiles of levodopa, carbidopa, and levodopa metabolite, 3-O-methyl

In order to deliver innovative and cost-effective IP multimedia applications over mobile devices, there is a need to develop a unified service platform for the future mobile Internet referred as the Next Generation (NG) all-IP network. It is convincingly demonstrated by numerous recent studies that modern multimedia network traffic exhibits long-range dependence (LRD) and self-similarity. These ch

In online auctions bidding frequency tends to increase towards the last minutes of the auction. This thesis investigates why bidders might choose to engage in last minute bidding, sniping, in Tradera auctions (Tradera is a Swedish subsidiary of eBay). Tradera uses a hard-close rule and a second-price rule. In hard-close auctions the dead-line occurs at a specific time, after which new bids are not

This master thesis has been written during the autumn of 2007 and in the month of January 2008. It investigates how the Lean philosophy can be used in Warehousing businesses. Further it gives example of tools that can help Warehousing companies to become Leaner in their business. There is a contradiction between Lean Thinking and Warehousing practice today, since Lean strive at being just in

The purpose of this study was to examine health promotion and ill-health prevention in the workplaces of the City District Committees in the City of Malmö. More specifically, we wanted to find what types of health problems there were and what kinds of strategies were applied to prevent them. Furthermore, the aim was to examine whether the leaders of the City of Malmö saw any effects of the strateg

Earlier the regional social insurance office was exposed to critisism because of bad administration and a lack of providing public service. Among other things the regional social insurance office was attacked because of long investigation hours and indinstinct working methods and was blamed for not being able to solve the unhealth in the society. This lead to the reformation of the previous region

This paper is a critique of an article in the Swedish magazine Filosofisk Tidskrift (Philosophical Magazine), in which professor Per Bauhn maintains that there is something wrong with having a group perspective in moral and political matters. In this article Bauhn makes three conclusions. The first one is that you violate Hume's law if you draw the conclusion that something is an oppression on

The purpose with this qualitative text analysis was to study how the sex roles of children are presented in children's books published in 2004 in comparison with children's books published 1972-74. The focus was to find patterns and differences. The study embraces eight books intended for children aged 5-9. The main results of the study showed that the girls were described to have a great

Populärvetenskaplig sammanfattning: Småvatten är en svacka eller hålighet som är vattenfylld året om. Dessa småvatten fyller många viktiga funktioner i naturen. De fungerar som utjämnare av flödesvariationer, uppehållsplats och födoplats för många djur och växter och som rena estetiska inslag i naturen, och inte minst som reningsplatser för oönskade näringsämnen så som kväve. Dessa småvatten har iWetlands play an important role in the ecosystem. They reduce the impact of flow flux in the drainage area, acts as upholder of biodiversity, as an esthetic and recreational component in the landscape and they have the ability to reduce nutrients such as nitrogen, and help preventing eutrophication in costal areas. The number of wetlands in Scania have, due to the intensified agriculture been redu

In recent years, application of ensemble models has been increased tremendously in various types of natural hazard assessment such as landslides and floods. However, application of this kind of robust models in groundwater potential mapping is relatively new. This study applied four data mining algorithms including AdaBoost, Bagging, generalized additive model (GAM), and Naive Bayes (NB) models to

BACKGROUND: Pramipexole, a dopamine agonist, has demonstrated antidepressant efficacy as an augmentation strategy in unipolar and bipolar depression. However, dopaminergic treatments are associated with impulse control disorders, including gambling disorder, and evidence regarding behavioural risks in psychiatric populations remains limited.METHODS: We conducted a nationwide register-based cohort

Objective: To describe the normal heart rate (HR) of healthy newborns ≥35+0 weeks’ gestation in the first 10 min after caesarean delivery (CD) with extrauterine placental transfusion, using dry-electrode ECG (NeoBeat). Design: Single-centre, prospective observational study. Setting: Norwegian County Hospital. Patients: Newborns ≥35+0 weeks’ gestation delivered by CD under regional anaesthesia were

Background: Upper tract urothelial carcinoma (UTUC) is rare, and contemporary data on real-world healthcare resource utilisation and costs are limited. The objective of this study is to describe long-term healthcare resource utilisation among patients with upper tract urothelial carcinoma (UTUC) and to identify clinical and treatment-related drivers of costs. Methods: We conducted a retrospective,

This thesis is a comparative analysis of five cases, in which criminal responsibility and mental disorder were in issue. Andrea Yates drowned her five children. John W. Hinckley Jr shot and injured President Ronald Reagan. Kjeldsen raped and assassinated a taxi driver on his way from Calgary to Banff. Mijailo Mijailovic attacked and killed the Swedish minister of foreign affairs Anna Lindh. Sara S

This dissertation examines the construction of P&amp&semicI club letters of undertaking by the English courts, and whether their approach can be criticised based on the legal nature of such contracts, the principles of construction which have been held applicable to them and their commercial purpose. A letter of undertaking serves as alternative security to an arrest and consists of a prom

Denna uppsats behandlar och syftar till att utreda möjligheten till umgänge mellan barn och dess mor- och farföräldrar, i enlighet med gällande svensk lagstiftning. Sådan umgängesrätt har genom de senare årtiondenas utveckling, enligt lagens ordalydelse, kommit att bli en rättighet tillägnad barnet. Enligt den tidigare gällande uppfattningen stod istället föräldrarnas intresse i fokus. UmgängesrätThis paper discusses the possibility of access between children and their grandparents according to Swedish law. In recent decades this access has become a right belonging to the child, according to the letter, in contrast to previous law where the parents’ interests were the priority. Since the reform in 1983 the right of access has become increasingly concentrated on the child’s needs and what i