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Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that if left untreated may lead to the development of cirrhosis. Previous studies on AIH patients have suggested that fibrosis and even cirrhosis can be reversed by medical treatment. The aim of this study was to evaluate the efficacy of medical treatment for protection of developing fibrosis and cirrhosis. A total of 258 liver biops

Capsazepine is known as a transient receptor potential channel vanilloid subfamily 1 (TRPV1) antagonist that inhibits bronchoconstriction evoked in animals by TRPV1 agonists. In this study, effects of capsazepine and chemically related analogues, so called capsazepinoids, were examined in vitro on contractile effects in human small airway preparations. Repeated cycles with 1 h of LTD4-free physiol

In this work a material model for hardening development in sheet metals during forming processes involving loading path changes is formulated. In particular, such hardening development is due to the formation and interaction of dislocation microstructures in the material, resulting in an evolution in the size, center and shape of the yield surface. Such yield surface evolution is accounted for in

A decomposition of the field of the wave equation in three dimensions is suggested. This wave splitting decomposes the field into two components such that in free space simple propagation properties are obtained. The inhomogeneous region is assumed to have a phase velocity variation that varies only in the radial coordinate r from the origin. The suggested wave splitting is a generalization of the

This paper presents a 28 GHz QVCO intended to be used in an 81-86 GHz E-band transceiver. E-band transceivers using e.g. 16 QAM modulation schemes are sensitive to I/Q phase error. Already a three degree error significantly degrades the bit error rate, and careful control of the phase error of the 28 GHz QVCO is therefore required. In the presented design the phase error can be tuned using four va

This thesis is a contribution to the understanding of the life and work of Arnold Schoenberg as well as to musical hermeneutics. The aims are (1) to scrutinize Arnold Schoenberg’s marital crisis of the year 1908, (2) to probe into the meanings of some representative musical works during this very period, and (3) to compare features in Schoenberg’s life and his creative work. A number of documents

The use of the analytical tools of classic and neo-classic economics has played a significant role in the study of Africa’s economic history since the 1970s. In this paper, we summon this body of work under the paradigm of Smithian growth models. Although different in techniques and approaches, this work shares a use of markets as the organising principle of the study. The aim of this paper is to

Background: Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it. Objectives: To investigate whether consumers with undesirable effects after using the UV-curing nail

The artistic doctoral project Singing in action – processes of vocal improvisation is an investigation of vocal improvised performance from my point of view as a classically trained singer and vocal improviser. It focuses on an artistic tradition which has its roots in medieval Provence and Italy (Wilén, 2013a) and which is an expanding classical vocal genre of today: opera and art song improvisat

A theoretical and experimental study of vibration isolation for a source on a lightweight floor structure is presented. The effectiveness of one-stage and two-stage isolator systems is studied. Approximate formulae are presented for both low and high frequency for the receiver, the floor structure. For the mobility, a comparison between approximate formulae, numerical exact results and experimenta

Purpose : to gain knowledge on how managers experience organizational core values, and to explore how the managers look upon the significance of such values in relation to their leadership. Theoretical framework : organisational culture (Schein) and action theory (Argyris & Schön). Regarding values, social influence and theories on motivation, studies by Rokeach , Sheldon and Elliot. Theory

A partir del fin de la Segunda Guerra Mundial se extiende, partiendo de los EEUU, una comprensión y uso de la ciencia subordinadas al proceso de producción. Esto determina el avance, sobre el campo científico, de un proceso de administración de la investigación y de la formación por parte del Estado y, a través de él, del aparato productivo. Esa subordinación de la actividad científica a la utilid

Objective/Background The objective was to analyze the long-term durability of intra-operatively placed Palmaz stents for type Ia endoleaks, and the evolution of aneurysm neck morphology. Methods This was a retrospective cohort study conducted at a tertiary referral centre. Patients treated between 1998 and 2012 were reviewed with regard to pre-, intra-, and post-operative data. Crude and relative

Innovation policy has emerged as a new field of economic policy during the last few decades. This paper explores the rationales for national innovation policies, as laid out in the existing literature on the subject, and considers what the lessons and challenges for theory and practice in this area are. Innovation policy attempts to influence innovation activity, often with the purpose of increasi

Inflammatory cytokines are potential modulators of infarct progression in acute ischaemic stroke, and are therefore possible targets for future treatment strategies. Cytokine studies in animal models of surgically induced stroke may, however, be influenced by the fact that the surgical intervention itself contributes towards the cytokine response. Community-dwelling domestic dogs suffer from spont

We analyzed seasonal influenza vaccination coverage among the Italian healthcare workers (HCW) in order to identify socio-demographic and clinical determinants of vaccination. We used data from the survey "Health and health care use in Italy," which comprised interviews of 5,336 HCWs For each respondent, information on socioeconomic, health conditions, self-perceived health and smoking status were