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Background: The modern style of goalkeeping in ice hockey is thought to predispose athletes to hip and groin problems. However, little is known about the magnitude of these problems in elite goalkeepers.Purpose: To describe the incidence, prevalence, and severity of hip and groin problems in elite ice hockey goalkeepers over the course of a single season.Study Design: Descriptive epidemiology stud

The bacterial superantigen (SAg) staphylococcal enterotoxin A (SEA) is a potent inducer of CTL activity and cytokine production in vivo. To engineer SAg for cancer immunotherapy, we genetically fused SEA to a Fab fragment of the C215 tumor-reactive antibody. Strong reduction of lung metastasis was seen in mice carrying established lung metastases of the poorly immunogenic B16-C215 melanoma after F

Understanding the biological mechanisms of l-dopa-induced motor complications is dependent on our ability to investigate these phenomena in animal models of Parkinson's disease. The most common motor complications consist in wearing-off fluctuations and abnormal involuntary movements appearing when plasma levels of l-dopa are high, commonly referred to as peak-dose l-dopa-induced dyskinesia. Parki

Classroom acoustics not always take the speaker's comfort into consideration. The purpose of the presented papers was to investigate voice use, vocal behavior and prevalence of voice problems in Swedish teaching staff. Ratings of features in the work-environment on voice use were explored in n = 487 teachers. Based on their answers the respondents were split into two groups: teachers with self-ass

Background: In vivo, high cerebral amyloid-β load has been associated with (i) reduced concentrations of Aβ42 in cerebrospinal fluid and (ii) increased retention using amyloid-β positron emission tomography. Although these two amyloid-β biomarkers generally show good correspondence, ~ 10-20% of cases have discordant results. To assess the consequences of having discordant amyloid-β PET and CSF bio

BACKGROUND: There is a growing interest to increase dietary fiber (DF) consumption due to the health benefits associated with this nutrient. Pulses are considered a good source of non-digestible carbohydrates. The aim of this study was to investigate the possibility of substituting semolina with chickpea flour to increase the indigestible carbohydrate content without altering the texture of the pa

PurposeThis paper aims to explore articulations of how individuals internalise official demands on handling COVID-19 and the function of social media in this process, and further to discuss this from a human rights’ perspective.Design/methodology/approachA thematic analysis of qualitative data from an international survey on COVID-19 and social media. The analysis was inspired by Berger and Luckma

Aim: The first Swedish National Guidelines for Ovarian Cancer (NGOC) were published in 2012. We aimed to evaluate surgical outcomes and survival in patients with stage IIIC-IV disease, before and after the NGOC implementation. Method: Women with primary epithelial ovarian cancer, FIGO stage IIIC–IV, registered in the Swedish Quality Registry for Gynecologic Cancer 2008–2011 and 2013–2016 were incl

Background: Previous work has demonstrated immunomodulatory, anti-tumor, anti-metastatic and anti-angiogenic effects of the small molecule quinoline-3-carboxamide tasquinimod in pre-clinical cancer models. To better understand the anti-tumor effects of tasquinimod in transplantable tumor models, we have evaluated the impact of the compound both on recruitment of myeloid cells to tumor tissue and o

This article gives an overview on the work available on methods for berry pomace processing, on methods for polyphenol extraction and on methods for polyphenol analysis. Additionally, previous reviews on fruit pomace have been identified and categorised with respect to pomace origin, and the scientific focus of the work. Data on berry pomace proximate composition are compiled, as are methods appli

Background: A general abdominal aortic aneurysm (AAA) screening program, targeting 65-year-old men, has gradually been introduced in Sweden since 2006 and reached nationwide coverage in 2015. The aim of this study was to determine the outcome of this program. Methods: Data on the number of invited and examined men, screening-detected AAAs, AAAs operated on, and surgical outcome were retrieved from

Background: We here study antibodies against phosphorylcholine (anti-PC) which we reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and autoimmune conditions. In previous studies, we determined that this inverse association is more pronounced at low levels with high risk and at high levels, with decreased risk. We compare individuals from Kitava, New Guinea (w

Amplification of the HER-2/neu (HER-2) proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend to alter their phenotype during disease progression. Circulating tumor cell (CTC) analysis may serve as an altern

Background: Chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cell (CRTh2) receptor antagonists is being investigated for asthma. Objectives: The aim of this study was to assess the effects of the CRTh2 receptor antagonist, AZD1981 (with/without inhaled corticosteroids [ICSs]), on lung function and asthma control. Patients and methods: Adults aged 18–60 years were enr

A large variety of rodent behavioral tests are currently being used to evaluate traits such as sensory-motor function, social interactions, anxiety-like and depressive-like behavior, substance dependence and various forms of cognitive function. Most behavioral tests have an inherent complexity, and their use requires consideration of several aspects such as the source of motivation in the test, th

BACKGROUND: The incidence of distal radius fracture has increased substantially during the last 50 years according to several studies that estimated the overall incidence in various general populations. The incidence of fracture classified according to severity has not been well documented. The aim of this population-based study was to estimate the overall and type-specific incidence rates of dist

Popular Abstract in Swedish Avhandlingen syftar till att bidra till förståelsen av hur det kan komma sig att kristendomen i början av det andra århundradet utvecklas till en icke-judisk religion. Att de judendom och kristendom idag uppfattas som två olika religioner är inte så märkligt. Dock, om man betänker att kristendomen ursprungligen var en del av det första århundradets judendom så är det egThis book attempts to answer the question of how it is possible that Christianity in the beginning of the second century C.E. had developed into a non-Jewish, Gentile religion. Since Christianity was originally one of many Jewish factions within the diversified Judaism of the period, and one that even primarily seems to have directed its attention to the people of Israel, the problem of its separa

In this book, ten doctoral students share and discuss a number of metho- dological concerns they have faced in the process of doing research. In the first part, “Capturing the field,” the contributors grapple over issues regarding how to define and demarcate the field of research, for instance in studies on immigrant organizations, red light districts on the Internet, and telephone interviewing. I

Popular Abstract in Swedish Med syftet att utvärdera tillämpbarheten av den ytvågsseismiska tekniken Spectral Analysis of Surface Waves (SASW), vilken används för bestämning av skjuvmodulen (Gmax), har fyra olika tillämpningsområden studerats. De fyra områdena har varit lokaler med naturliga jordförhållanden, lokaler där enbart icke-förstörande metoder normalt är möjliga att använda, test av vägbaWith the main aim to test the applicability of the surface wave seismic technique Spectral Analysis of Surface Waves (SASW), used for determination of the shear stiffness (shear modulus - Gmax), four areas of applications have been studied. The four areas have been sites with natural geological conditions, sites where non destructive testing is necessary, pavement testing and multichannel testing.

Expansive cements are utilised in special applications to improve properties such as cracking caused by drying shrinkage. Several types of expansive cements exist and the main hydration product responsible for the expansion is ettringite, [Ca₃Al(OH)₆]₂(SO₄)₃·26H ₂O. The importance of the cement phase containing alumina is well known