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The logistics concepts at BMW's engine factory in Munich are continuously revised, in order to optimise the logistics process. The objective of this thesis work is to study if it would be profitable to use an individual, reusable package for transporting and handling engine wiring harnesses in order to prevent damages. Approach The work was divided into different stages. First the flow of th
The aim of this paper was to examine how social workers' comprehension of the need of financial aid exists in, and is influated by, the organisation they work in. To investigate this, we asked ourself questions concerning how the social worker view the way that the finicial aid-system and work surrounding it is formed, whether the social worker's understanding of the need of financial aid
Context. The central molecular zone (CMZ) is a ∼200 pc region around the Galactic centre. The study of star formation in the central part of the Milky Way is of great interest as it provides a template for the closest galactic nuclei. Aims. We present a spectroscopic follow-up of photometrically selected young stellar object (YSO) candidates in the CMZ of the Galactic centre. Our goal is to quanti
Socioeconomic, ethnic and gender disparities in Chronic Obstructive Pulmonary Disease (COPD) risk are well established but no studies have applied multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) within an intersectional framework to study this outcome. We study individuals at the first level of analysis and combinations of multiple social and demographic catego
Raw milk may be a risk for public health if it is contaminated with zoonotic pathogens. To study the prevalencein unpasteurized milk from Swedish farms, bovine and small ruminant dairy farms were sampled. Since thesampling method and transport conditions may influence the outcome of analyses, efforts were made to optimizethe methodology. Culturing of bacteria was done from in-line milk filters col
Background: Sleep disturbances are common among older people (>65 years). Further, long-term use of sedative-hypnotics in older people is associated with morbidity and mortality. However, older people represent a large span of life years, and few studies have included the oldest-old above 85 years. Aim: To investigate and compare sleep quality, use of hypnotics and sleeping habits in different age
To gain entry into target cells, HIV-1 binds to CD4 via the viral glycoprotein gp120. This interac-tion initiates a series of events including binding of a coreceptor, CCR5 and/or CXCR4, and ulti-mately leads to gp41-mediated fusion of the viral and cell membranes. CCR5-restricted (R5) vi-ruses predominate in early, asymptomatic stages of the infection. Emergence of viruses able to use CXCR4 inste
Industrial robots are fast and accurate when working with known objects at precise locations in well-structured manufacturing environments, as done in the classical automation setting. In one sense, limited use of sensors leaves robots blind and numb, unaware of what is happening in their surroundings. Whereas equipping a system with sensors has the potential to add new functionality and increase
In this paper the impact of different meals and rapid insulin were estimated as Finite Impulse Response Models from a data set of 18 patients. Based on these models short-term individualized predictors were tested for 20 and 60 minute prediction. The predictors were evaluated using Clarke Grid Analysis and had on average more than 94 % and 75 % in the A zone and less than 1 % and 3 % in the erroro
This paper presents the elaboration of an experimentally validated model of a continuous cross-flow atomic layer deposition (ALD) reactor with temporally separated precursor pulsing encoded in the Modelica language. For the experimental validation of the model, in situ quartz crystal microbalance (QCM) diagnostics was used to yield submonolayer resolution of mass deposition resulting from thin fil
Background: Knowledge of sitting and standing performance in a total population of children with cerebral palsy (CP) is of interest for health care planning and for prediction of future ability in the individual child. In 1994, a register and a health care programme for children with CP in southern Sweden was initiated. In the programme information on how the child usually sits, stands, stands up
Background: The widening socioeconomic gap in smoking during pregnancy remains a challenge to the Swedish antenatal care services. However, the influence of cultural factors in explaining the socioeconomic differences in smoking during pregnancy is not clear among the immigrant women. The aim of this study was to investigate whether the development of smoking prevalence among pregnant immigrant wo
We have studied the geometry and singlet-triplet energy difference of two mono-nuclear Ni2+ models related to the active site in [NiFe] hydrogenase. Multiconfigurational second-order perturbation theory based on a complete active-space wavefunction with an active space of 12 electrons in 12 orbitals, CASPT2(12,12), reproduces experimental bond lengths to within 1 pm. Calculated singlet-triplet ene
Although estrogen receptor-alpha (ERalpha) is a marker used to identify breast cancer patients most likely to benefit from endocrine therapy, approximately 50% of ERalpha-positive breast carcinomas are resistant to tamoxifen. Preclinical studies have shown that phosphorylation of ERalpha at serine-118 (ERalphaS118-P) is required for tamoxifen-mediated inhibition of ERalpha-induced gene expression.
Earlier studies on women's health and drinking and the contemporary associated risk factors have highlighted the need for more complex approaches in understanding the pathways into women's problem drinking. Research, from both social science and from occupational therapy models, has underlined the importance of deconstructing the often dichotomized way of investigating women's daily lives (such as
The aim of this paper is to provide a systematic review of the evidence of the impact on economic growth of investments in maternal--newborn health (MNH). The methodology used for the review includes a systematic search for published literature in relevant electronic databases. In the paper, we review five studies: four empirical and one theoretical. One of the empirical papers measures health by
Hematopoietic stem cells (HSCs) are primitive tissue-specific somatic stem cells, responsible for the maintenance and replenishment of the bone marrow (BM) and subsequently the entire blood system. The never-ending ability to differentiate into all the mature hematopoietic lineages makes these HSCs attractive candidates for use in future regenerative medicine. HSCs are balanced between different f
Colonized bank voles (Clethrionomys glareolus) originating from Sweden developed type 1 diabetes. Animals became polydipsic, glucosuric, and hyperglycemic and gradually developed a lethal ketoacidosis. Pancreas in animals with end-stage disease showed total destruction of islet cells. Interestingly, also a high proportion of wild bank voles in cyclic populations that were trapped at (or close to)
