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Aims:  To evaluate outcome in the first generation of children with end-stage heart disease to whom heart transplantation was available. Methods:  Retrospective review of all 135 Swedish children <18 years old listed for heart transplantation 1989-2009, followed to December 31, 2009, including 74 (55%) with cardiomyopathy and 61 (45%) with congenital heart disease; 34 (25%) were infants (<1 year).

The purpose of this study was to compare the non-invasive 3D pseudo-continuous arterial spin labelling (PC ASL) technique with the clinically established dynamic susceptibility contrast perfusion magnetic resonance imaging (DSC-MRI) for evaluation of brain tumours. A prospective study of 28 patients with contrast-enhancing brain tumours was performed at 3 T using DSC-MRI and PC ASL with whole-brai

AIM: To investigate plasma levels of the neutrophil-borne heparin-binding protein (HBP) in patients with induced hypothermia after cardiac arrest (CA), and to study any association to severity of organ failure, incidence of infection and neurological outcome. METHODS: This study included 84 patients with CA of mixed origin who were treated with hypothermia. Plasma samples from 7 time points during

Background Estimation of skin diseases in the community is challenging because we do not easily have access to the nonhealthcare-seeking population. A potential tool is a questionnaire asking for self-reported skin complaints. Such an instrument has not yet been developed. Objectives To validate a simple instrument assessing skin morbidity in the general adult population, to predict clinical skin

Purpose: To explore work related and personal facilitators and barriers for return to work (RTW) and stay at work after stroke. Materials and methods: Twenty individuals post-stroke (median age 52 years; seven women) were interviewed in focus groups. Data were analyzed by using qualitative content analysis. Results: An overall theme “Work conditions, support and changed personal priorities influen

Stapylococcus aureus is a common infectious agent in e.g. sepsis, associated with both high mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has repeatedly been shown to enhance the virulence of S. aureus. Combined with an unhindered spread of multi drug-resistant strains, this has triggered research into novel anti virulence (i.e. anti α-hemolysin) drugs. Their func

Background and purpose — Fast-track care programs have been broadly introduced at Swedish hospitals in elective total hip and knee replacement (THR/TKR). We studied the influence of fast-track programs on patient-reported outcomes (PROs) 1 year after surgery, by exploring outcome measures registered in the Swedish arthroplasty registers. Patients and methods — Data were obtained from the Swedish K

In this communication, a novel planar structure-shared diverse two-port ultrawideband (UWB) antenna with high isolation and common ground is proposed based on a new slot-loaded method. A tapered slot with an end-fire radiation pattern is etched in the top middle section of a coplanar waveguide (CPW)-fed printed monopole antenna to reduce its effects on the monopole mode. The two-port UWB antenna f

Background. Type 2 diabetes (T2D) is a complex heterogeneous disorder affecting multiple organs. Gene expression studies in organs central to T2D, such as pancreatic islets and skeletal muscle will help elucidate and disentangle molecular mechanisms underlying T2D. Deep phenotyping using commonly measured clinical variables allows for the identification of clinically relevant T2D subgroups,

The overall aim of this thesis work is to characterize artificial biomolecular motors, specifically the Lawnmower, a motor based on the burn bridges mechanism, and the Tumbleweed, a protein motor that employs ligand specific DNA-proteins binding to step along DNA. An overview of their operational principles is given, and initial results of our studies are presented, along with a review of currentl

Nätläkare, vårdgivare som tillhandahåller sjukvårdstjänster via smartphoneappar, har gått från att vara perifera inslag i den svenska sjukvården till att på allvar utmana det konventionella sättet att bedriva sjukvård. Den tillgänglighet som nätläkare erbjuder är oöverträffad men alla patientgrupper har inte sett sin tillgång till vård förbättras i samma utsträckning tack vare nätläkare.Syftet med

Intrinsic self-healing materials have received significant attention due to the characteristic recovery after damage properties through reversible dynamic covalent and non-covalent interactions. Furthermore, functional recovery with reliable mechanical properties are highly keen as protective coatings, specifically for devices and sensors vulnerable to abrasion in severe environments. Here, we pre

Serialization is an old narrative strategy and a form of publication that can be traced far back in literary history, yet serial narratives are as popular as ever. This book investigates a resurgence of serial narratives in contemporary literary culture.Analyzing series as diverse as Mark Z. Danielewski’s experimental book series The Familiar; audiobook series by the Swedish streaming service Stor

For polarization-resolved reflection experiments such as ellipsometry, not only is high reflectivity in a wide spectral range required for mirrors but also the quality of their polarization response is important. Furthermore, for VUV ellipsometry, optimal angles of incidence at the sample are between 45° and 60° with respect to the surface normal. In the best case, a setup should even allow variab

This paper reports the first Computational Fluid Dynamics (CFD) model developed for biomass pyrolysis oil spray combustion using Finite-Rate Chemistry (FRC) approach. To make the CFD calculations feasible, a reduced mechanism for modeling the combustion of biomass Fast Pyrolysis Oil (FPO) based on the POLIMI 1412 mechanism and a model for eugenol oxidation was developed. The reduced mechanism cons

Importance: Family and genetic approaches have traditionally been used to evaluate our diagnostic concepts. Using a novel method, the family genetic risk score (FGRS), can we validate the genetic architecture of major affective and psychotic disorders in a national Swedish sample? Objective: To determine whether FGRSs, calculated for the entire Swedish population, can elucidate the genetic relatio

The surface area of a building that could potentially be used for Building Integrated Photovoltaics would increase dramatically with the availability of transparent solar cells that could replace windows. The challenge is to capture energy from outside the visible region (UV or IR) while simultaneously allowing a high-quality observation of the outside world and transmitting sufficient light in th

The knowledge about the hydraulic conductivity of the subsurface is crucial to know as it is a main parameter for groundwater flow characterization within an aquifer. The geophysical method time-domain Induced Polarisation has been shown to be useful for estimating the hydraulic conductivity. By using a new inversion approach, where we directly invert for hydraulic properties as inversion paramete

Objectives: Previous research suggests that governments usually gain support during crises such as the Covid-19. However, these findings are based on rating scales that only allow us to measure the strength of this support. This article proposes a new measure of how voters evaluate Prime Ministers (PM) by asking for descriptive keywords that are analyzed by natural language processing.Methods: By