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Aim: To study the development of early knee osteoarthritis (OA) in subjects with and without risk factors for knee OA. Methods: We studied 340 subjects from the Osteoarthritis Initiative (OAI), aged 45–55 years (51% women), free of radiographic knee OA at baseline (n = 294 with and n = 46 without knee pain and other OA risk factors). At baseline, 24, 48, 72 and 96 months we compared the two groups

BACKGROUND: Patients with acute coronary occlusion (ACO) may not only have ischemia-related ST-segment changes but also changes in the QRS complex. It has recently been shown in dogs that a greater ischemic QRS prolongation (IQP) during ACO is related to lower collateral flow. This suggests that greater IQP could indicate more severe ischemia and thereby more rapid infarct development. Therefore,

Lymph node metastasis is the most important prognostic characteristic of colorectal cancer. Carcinoembryonic antigen messenger RNA was shown to detect tumor cells that have disseminated to lymph nodes of colorectal cancer patients and to be at least as good as the hematoxylin and eosin method to predict survival in colorectal cancer patients. CXCL17 was recently shown to be ectopically expressed i

BACKGROUND: An adequate amount of prepaid resources for health is important to ensure access to health services and for the pursuit of universal health coverage. Previous studies on global health financing have described the relationship between economic development and health financing. In this study, we further explore global health financing trends and examine how the sources of funds used, typ

Objective: The aim of this study was to evaluate the use of intravesical treatment and cancer-specific survival of patients with primary carcinoma in situ (CIS). Materials and methods: Data acquisition was based on the Swedish National Registry of Urinary Bladder Cancer by selecting all patients with primary CIS. The analysis covered gender, age, hospital type and hospital volume. Intravesical tre

Background & Aims: Primary liver cancer is the second most common cause of death from cancer worldwide. In the western world, the majority of liver malignancies consist of colorectal metastases. Liver resection is the primary treatment for cure in liver tumor disease. Hepatic injuries such as steatosis, steatohepatitis, fibrosis and sinusoidal obstruction syndrome, which could be a consequence

Think H2O! – An educational partnership to raise students’ awareness of the water challenges Introduction: To secure future access to safe water is one of the most important sustainability challenges, on local and global level. Water is a cause of conflict and cooperation in an increasingly complex world. This crucial challenge requires a transdisciplinary approach (Segalàs & Tejedor, 2013) a

Objectives The aim of this research is to study education, income and immigration as risk factors for high hemoglobin A1c (HbA1c >70 mmol/mol (8.6%)) when diagnosed with type 2 diabetes (T2D) or latent autoimmune diabetes in the adult (LADA). Research design and methods Patients were included from the All New Diabetics in Scania study (2008-2013). Level of education, disposable income and immigrat

BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of risk factor exposure and attributable burden of disease. By providing estimates over a long time series, this study can monitor risk exposure trends critical to health surveillance and inform policy debates on the importance of addressing risks in context.METHODS: We u

Globalt sett lever 8 av 10 människor i miljöer där luftföroreningar i form av små luftburna partiklar ligger över riktlinjer satta av världshälsoorganisationen WHO. WHO uppskattar även att luftföroreningar ligger bakom 3.7 miljoner dödsfall varje år. Värst är det i delar av Asien, men även här i Sverige är luftkvaliteten ett problem; i Skåne t ex bedöms den genomsnittliga livslängden förkortas medAtmospheric aerosols affect climate, but to what degree still remains one of the largest uncertainties in global climate models. To improve the representation of aerosols in future climate models we need a greater understanding of aerosol processes. In this thesis the process-based model ADCHEM has been used and further developed to study aerosol processes. Specifically; new particle formation and

In this paper, a study on the performance of surface irrigation of date palms in a Tunisian arid area (Douz oasis) is presented. The study is conducted in 16 plots with various sizes and soil textures over a 4-year period (2012–2015). In the first step, an assessment of total water requirements of the date palms is carried out. Then, the surface irrigation performance is analyzed using three indic

A new foundation solution using a cellular raft with an active stabilisation system is proposed in this work. A comparative study of the new foundation and a traditional raft is performed. This study focuses on comparing the load capacity of the mentioned foundation solutions. The results illustrate that a cellular raft with an active stabilisation system gives a substantial enhancement of the loa

Background: Strenous exercise stimulates the hypothalamic-pituitary (HP) axis in order to ensure homeostasis and promote anabolism. Furthermore, exercise stimulates a transient increase in the neurotrophin brain-derived neurotrophic factor (BDNF) suggested to mediate the anxiolytic effects of exercise. Athletes with secondary functional hypothalamic amenorrhea (FHA) have been reported to have lowe

BACKGROUND: Noroviruses are the major cause of viral gastroenteritis. Disease transmission is difficult to prevent and outbreaks in healthcare facilities commonly occur. Contact with infected persons and contaminated environments are believed to be the main routes of transmission. However, noroviruses have recently been found in aerosols and airborne transmission has been suggested. The aim of our

This article analyzes instances of refusal to eat or drink due to the fear of poisoning and contamination amongst favela youth in Brazil. These particular occurrences of refusal shed light on refusal’s potency as a way of managing complex social entanglements and instrumental in asserting agency. Considering that interlocutors had come of age without many formal institutions present, they needed p

Myxoinflammatory fibroblastic sarcoma (MIFS) has recurrent genetic features in the form of a translocation t(1;10)(p22-31;q24-25), BRAF gene fusions, and/or an amplicon in 3p11-12 including the VGLL3 gene. The breakpoints on chromosomes 1 and 10 in the t(1;10) cluster in or near the TGFBR3 and OGA genes, respectively. We here used a combination of deep sequencing of the genome (WGS), captured sequ

Amputation of a hand is a life-changing event, and the loss of motor and sensory functions leads to disability and has devastating effects on the individual. What is normally performed using two hands must be solved with only one, and the loss also affects body balance and body posture. In addition, amputation of a hand has psychological effects, and has an influence on social life, participation,