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We report 17 new solar activity cycles with periodicities ranging from 1,700 to 18,000 years. Using Bayesian spectral analysis we determined for each cycle period, amplitude and phase for the past 145,000 years. These results were obtained by analyzing 10Be in the 2775 m long EDML ice core from Dronning Maud Land, Antarctica. In addition, we have augmented the 10Be data with synchronous ice accumu
Framväxten och övergången till en alltmer kunskapsbaserad ekonomi har de senaste decennierna omformat grunderna för arbete, möjligheter och politiska attityder i de flesta avancerade ekonomier. Mycket av den offentliga och akademiska debatten har i detta sammanhang betonat ökande regionala klyftor, växande ojämlikheter, ökad osäkerhet, minskad social rörlighet och i kölvattnet av detta också ett vThe transformation to the knowledge economy has reshaped the foundations of work, opportunity, and political sentiment across advanced democracies. Much of the public and academic debate has emphasized deepening regional divides, increasing inequalities, growing precarity, the erosion of upward mobility, and growing social discontent.This PhD thesis explores the geographies of low-income work in S
This master's thesis sets out to explore information literacy in a contextualized learning environment with emphasis on students at a vocationally oriented program in the Swedish upper secondary school. The concept of information literacy is widely discussed and furthermore a common subject for research within the field of Library and Information Science. Information literacy can be described
United States is one of the two countries in the world that have not ratified the convention on the rights of the child, and one of the few countries that sentences children less than 18 years to life in prison without parole. Besides this, corporal punishment is legal in all the states of USA. This essay is aimed at researching how these three factors affect one another in the American context an
AIM: The purpose of the present study was to investigate the radiosensitivity of the prostate cancer cell lines LNCaP, DU145, and PC3 when irradiated with beta particles emitted from (177)Lu, and to compare the effect with irradiation using alpha particles or gamma rays.MATERIALS AND METHODS: Cells were irradiated with beta particles emitted from (177)Lu, alpha particles from (241)Am, or gamma ray
Background: Active surveillance (AS) is commonly used for men with low-risk prostate cancer (PCa). When life expectancy becomes too short for curative treatment to be beneficial, a change from AS to watchful waiting (WW) follows. Little is known about this change since it is rarely documented in medical records. Objective: To model transition from AS to WW and how this is affected by age and comor
Combining data from spontaneous face-to-face conversations in the London-Lund Corpus (LLC) of spoken British English and a laboratory experiment, this paper analyses the dynamic nature of I think constructions in dialogue. We make use of the functional category of ENGAGEMENT in APPRAISAL theory as an analytical tool (Martin & White, 2005). More precisely, we examine whether I think constructio
Impulsivity is common in Parkinson's disease even in the absence of impulse control disorders. It is likely to be multifactorial, including a dopaminergic 'overdose' and structural changes in the frontostriatal circuits for motor control. In addition, we proposed that changes in serotonergic projections to the forebrain also contribute to response inhibition in Parkinson's disease, based on precli
Recent studies have reported a very high frequency of noncoagulating milk in Swedish Red cows. The underlying factors are not fully understood. In this study, we explored rennet-induced coagulation properties and relative protein profiles in milk from native Swedish Mountain and Swedish Red Polled cows and compared them with a subset of noncoagulating (NC) and well-coagulating (WC) milk samples fr
Background: Whether surgeons perform better utilising a robot-assisted laparoscopic technique compared with an open approach during prostate cancer surgery is debatable. Objective: To report erectile function and early oncologic outcomes for both surgical modalities, stratified by prostate cancer risk grouping. Design, setting, and participants: In a prospective nonrandomised trial, we recruited 2
Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as
Background: Apolipoprotein M (apoM) is a 25-kDa apolipoprotein present in 5% of high-density lipoprotein (HDL) particles. It is suggested to be anti-atherogenic and to play a key role in sustaining endothelial barrier integrity. SLE patients have increased cardiovascular disease risk, and we aimed to investigate if apoM levels reflect endothelial function in SLE. Since apoM plasma levels decrease
Objectives: To investigate the preoperative prognostic value of molecular subtypes in relation to clinical information, histopathological findings, and molecular markers for patients with bladder cancer treated with radical cystectomy. Patients and methods: After standard preoperative staging, a population-based cohort of 519 patients underwent radical cystectomy between 2006 and 2011. Following
Introduction Angiotensin-receptor blockers may exert favourable anti-arrhythmic effects in atrial fibrillation (AF), but their mechanisms are not fully understood. In this study, we tested the hypotheses that (i) candesartan reduces atrial fibrillatory rate and (ii) fibrillatory rate and its response to candesartan are related with the outcome of cardioversion. For this purpose, a post hoc subanal
Dyskinesia seen in the off-state, referred as graft-induced dyskinesia (GID), has emerged as a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. Although the mechanism underlying the appearance of GID is unknown, in a recent clinical study the partial 5-HT(1A) agonist buspirone was found to markedly reduce GID in three grafted patients, who showed signifi
Ossifying fibromyxoid tumor (OFMT) is a soft tissue tumor of unknown lineage. Although most cases are histologically and clinically benign, some show malignant morphological features and local recurrences are not uncommon; a few may even metastasize. In the present study, cytogenetic analysis identified different structural rearrangements of chromosome band 6p21 in tumor cells from three cases of
Background: High-circulating level of parathyroid hormone (PTH) is associated with elevated mortality in dialysis patients. The Japanese Society for Dialysis Therapy guideline suggests a lower PTH target than other international guidelines; thus, PTH control may differ in Japan compared with other regions, and be associated with mortality. Methods: We analyzed data from hemodialysis patients with
Understanding how and why some groups have become more species-rich than others, and how past biogeography may have shaped their current distribution, are questions that evolutionary biologists have long attempted to answer. We investigated diversification patterns and historical biogeography of a hyperdiverse lineage of Lepidoptera, the geometrid moths, by studying its most species-rich tribe Boa
Incorporating the conceptual resources of the ontological argument for the existence of God into the underlying rationale of the cosmological ditto, I here present and defend a ‘cosmontological’ synthesis: an a posteriori argument for the existence of an all-perfect GOD: a being who, in virtue of being whatever it is better to be than not to be, is that than which a greater cannot be thought. Cent
